Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Mechanical Engineer, Scientific Instrumentation

$150k - $180k

Homeworld Collective Inc

A Bit About Us We are Arcadia Science, an evolutionary biology company founded and led by scientists. Our mission is to turn natural innovations into real‑world solutions by developing systematic and quantitative approaches to leveraging biology for therapeutics R&D. We share our research as openly as possible to accelerate discovery and make our work broadly useful. About the role The Mechanical Engineer will be part of the Foundry, Arcadia’s division at the interface between R&D and commercial deployment. The goal of this division is to take scientifically validated tools and capabilities from the research team and productionize them for broader use. The Foundry’s first focus is Raman spectroscopy. This role will report directly to the CEO. You will start with an effort to transform AutoOpenRaman, an open‑source, automated Raman spectrometer we developed for biological research, into a compact, safe, manufacturable benchtop instrument. That means designing a Class 1 laser enclosure, defining the mechanical architecture of the integrated system, and creating a build process reproducible enough to scale. You will work closely with optical and software engineers and the scientists who will use the instrument every day. From there, you will help define what external deployment looks like, contributing to a product that can be quickly and affordably placed in partner labs and companies. What you'll work on Define the mechanical envelope of the InstantRaman enclosure, working within the constraints of the optical path, motorized stage, and Class 1 laser safety requirements Design and prototype an enclosure that achieves Class 1 laser safety certification and is manufacturable at small‑scale production runs (10–50 units) Own the mechanical bill of materials, tolerancing, and assembly documentation for reproducible builds Consolidate the current electronics (stage controller, shutter, calibration light source, laser) into a single integrated mechanical system with clean cable routing and accessible service points Work with the optical instrument engineer to co‑develop a compact optical path that fits within the enclosure envelope, enclosure design drives the layout, not the other way around Engage fabrication vendors, sheet metal shops, and laser safety review as needed Develop design‑for‑manufacturability (DFM) documentation ahead of any transition from prototype to production What we're looking for You’ll be well‑suited for this role if you have: BS or MS in mechanical engineering or a closely related field, with hands‑on experience designing and building scientific or analytical instruments Experience designing enclosures or housings for regulated or safety‑critical hardware (laser systems, high‑voltage electronics, or similar) Proficiency in CAD (SolidWorks, Fusion 360, or equivalent) including tolerancing, assembly modeling, and drawing packages for fabrication Experience with sheet metal design, vendor sourcing, and iterating through fabrication cycles Ability to collaborate tightly with optical and software engineers, you understand that your mechanical design decisions affect optical alignment stability, thermal behavior, and software‑controlled motion Familiarity with electromechanical integration: specifying and installing stepper motor stages, limit switches, interlocks, or similar embedded systems Ability to communicate with biologists and understand what actually matters for a life science instrument: ergonomics, sample loading, serviceability, and ease of use are part of the design problem Nice to have Direct experience with laser systems or enclosed laser instrumentation, including Class 1 or Class 3B/R safety design Familiarity with optical bench layouts, cage systems, or Raman/spectroscopy instruments Experience with design for manufacturability and transitioning from prototype to small‑scale production Experience with relevant experimental workflows and the physical realities of laboratory environments (vibration, humidity, bench space constraints) $150,000 - $180,000 a year. Successful applicants can expect to be compensated between $150,000–$185,000 with benefits and a competitive equity offering, depending on experience level. The position will require the individual to be on‑site at our Emeryville, California headquarters. Arcadia is an equal opportunity workplace; we welcome people from all backgrounds and communities. #J-18808-Ljbffr Homeworld Collective Inc

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Mechanical Engineer, Scientific Instrumentation in Emeryville, CA vacancy
  • $150k - $180k

    Homeworld Collective Inc is seeking a Mechanical Engineer to join their Emeryville, California team. This role focuses on transforming advanced...  ...or MS in Mechanical Engineering and hands-on experience in instrument design. The salary ranges from $150,000 to $180,000... 
    Suggested

    Homeworld Collective Inc

    Emeryville, CA
    1 day ago
  • $160k - $200k

     ...Summary This position requires an instrument systems engineer to lead the development of spaceflight...  ...the design, assembly, and test of scientific instruments and payload systems (primarily...  ...and engineering fields such as mechanical. Ensure that the instrument design... 
    Scientific
    Full time
    Part time
    For contractors
    H1b
    Remote work

    University of California Berkeley

    Berkeley, CA
    4 days ago
  • $160k - $200k

    Position Summary This position requires an instrument systems engineer to lead the development of...  ...in the design, assembly, and test of scientific instruments and payload systems (primarily...  ...and engineering fields such as mechanical. Verify that the instrument design... 
    Scientific
    Full time
    For contractors
    H1b
    Remote work

    University of California

    Berkeley, CA
    2 days ago
  •  ...world modeling, but the broader opportunity is advancing scientific research into intelligence itself. Founded by Stanford and...  ...matter at civilizational scale, join us. We’re hiring a mechanical / CAD engineer to lead the mechanical design of our wearable capture hardware... 
    Scientific
    Shift work

    Human Archive

    San Francisco, CA
    1 day ago
  •  ...platform: Physical AI that can operate scientific instruments with human‑level dexterity....  ...a team of passionate, mission‑driven engineers from companies like Tesla, Amazon, SpaceX...  ...this role, you will: Intern in our Mechanical Engineering team, focusing on building... 
    Scientific
    Full time
    Internship
    Work at office
    Local area
    Flexible hours

    Medra

    San Francisco, CA
    1 day ago
  • $125k - $140k

     ...As product complexity increases and the cost of failure and scientific labor rises, the industry is shifting toward automation....  ...action, visit and follow us on LinkedIn. About the Role As a Mechanical Engineer in the Multiply Labs team, you will apply your engineering... 
    Scientific
    H1b
    Work at office
    Visa sponsorship
    Flexible hours
    Shift work

    Multiply-Labs

    San Francisco, CA
    3 days ago
  •  ...performance space telescopes, democratize the scientific process, and build tools for exploring...  ...We’re looking for an optomechanical engineer to design and build the structures that...  ...in the first 90 days Produce a v1 mechanical architecture for the optical bench and... 
    Scientific
    Work from home

    Cosmic Frontier Labs

    San Francisco, CA
    4 days ago
  •  ...We’re building a small team of exceptional, hands‑on engineers to make this happen. Mechanical, electrical, hardware, computer, and process. We’ll own...  ...work across whether we are building, applying a deeply scientific mindset to characterize tools, intuit potential... 
    Scientific
    Work at office
    Visa sponsorship
    Night shift

    Atomicsemi

    San Francisco, CA
    4 days ago
  • $221.9k - $308.1k

     ...Principal Mechanical Engineer – Advanced Automation & Systems Integration San Francisco (Brisbane), CA Vivodyne creates human data...  ...prioritizes continuous learning, rigorous engineering and scientific standards, and bold problem-solving. If you're excited... 
    Scientific
    Full time
    Local area

    Vivodyne

    San Francisco, CA
    2 days ago
  • $123.6k - $170k

     ...outcomes, operational advancement, scientific discovery and cutting‑edge manufacturing...  .... We're looking for a high‑energy, Mechanical HVAC Engineer to focus on our Data Center market....  ..., the development of Process and Instrumentation Diagrams (P&IDs), and general arrangements... 
    Scientific
    Full time
    Work at office
    Remote work

    Jacobs

    San Francisco, CA
    5 days ago
  •  ...for a self‑motivated Packaging Simulation Engineer who is proficient in FEM simulation with...  ...Qualifications Proven capability in mechanics and mathematics. Hands‑on experience of...  ...software tools and expert in MATLAB and/or Scientific Python. Hands‑on experience of Gen‑AI... 
    Scientific

    Apple Inc.

    San Francisco, CA
    5 days ago
  • $180k - $235k

     ...Defense. We are seeking a highly skilled Autonomy Perception Engineer to join our Perception Engineering team. In this role, you...  ...maintainable code. Solid understanding of metrics, data analysis, and scientific evaluation. A team player. You take ownership and work with... 
    Scientific
    Temporary work
    Work at office
    Visa sponsorship
    Flexible hours

    Kodiak

    San Francisco, CA
    5 days ago
  •  ...with Astellas, we are committed to patient-centric design, scientific and engineering excellence, and cross-functional teamwork. These...  ...kind technologies into the clinic and closer to patients. Mechanical Engineer II The Mechanical and Manufacturing Engineering... 
    Scientific
    Full time
    Contract work
    Work at office
    Flexible hours

    iota Biosciences, Inc.

    Alameda, CA
    2 days ago
  • $185k - $225k

     ...About the role The Optical Hardware Engineer will be part of the Foundry, Arcadia's...  .... The goal of this division is to take scientifically validated tools and capabilities from the...  ...external deployment by optimizing the instrument (e.g., increasing the signal-to-noise,... 
    Scientific

    Arcadia Science

    Emeryville, CA
    14 days ago
  •  ...Job Title Senior Automation Engineer in Robotics Job Description About JSat Automation At JSat Automation we believe that by...  ...resources they need to overcome obstacles in their quest for scientific discovery and change, we can more broadly improve the daily lives... 
    Scientific
    Contract work
    For subcontractor
    Work at office

    E Tech Group

    Oakland, CA
    1 day ago
  •  ...innovative biological imaging projects. Candidates must hold a Bachelor's degree and possess skills in programming and computational biology. This role promises exposure to groundbreaking imaging technologies and collaborative scientific environments. #J-18808-Ljbffr... 
    Scientific

    University of California Berkeley

    Berkeley, CA
    3 days ago
  • $120k - $170k

    Instrumentation and Controls Project Engineer Overview Affiliated Engineers, Inc. (AEI) is a leading, multidisciplinary consulting engineering firm and...  ...biomedical research, and enabling the next generation of scientific discovery and technological innovation through... 
    Scientific
    Work at office
    Flexible hours

    Affiliated Engineers, Inc.

    San Francisco, CA
    5 days ago
  • $150k - $180k

     ...A leading life sciences organization in California is seeking a Project Director to operationalize scientific programs related to experimental and computational biology. This role requires a PhD and at least three years of post-PhD experience in managing complex research... 
    Scientific

    Arcadia Science LLC

    Emeryville, CA
    3 days ago
  •  ...simulation results, delivery of the hybrid model results into a graphical user interface, presentation of results at appropriate scientific workshops and conferences, and preparation and submission of scientific manuscripts to appropriate peer-reviewed journals. #J-18... 
    Scientific

    University of California

    Berkeley, CA
    2 days ago
  •  ...seeking a Medical Science Liaison for the Mid-Atlantic Region. This role involves engaging with national thought leaders, providing scientific information about Ipsen's innovative therapies, and supporting clinical research initiatives. The ideal candidate will have a... 
    Scientific

    Ipsen Group

    Berkeley, CA
    1 day ago
  • $130k - $180k

     ...one year of post-doctoral experience, coupled with expertise in computational biology and a strong ability to communicate complex scientific ideas. The compensation ranges from $130,000 to $180,000 annually, reflecting experience level and is complemented by benefits.... 
    Scientific

    Arcadia Science

    Emeryville, CA
    2 days ago
  • $150k - $275k

     ...Emeryville, California is seeking an Optical Engineer at Associate or Senior level to join...  ...and innovating optical approaches for scientific applications. The ideal candidate will...  ...or physics, and hands-on experience in instrumentation design. The position offers a... 
    Scientific

    Arcadia Science

    Emeryville, CA
    4 days ago
  •  ...Responsibilities include maintaining simulation libraries, delivering model results in a user-friendly interface, and preparing scientific manuscripts. Ideal candidates will have a PhD in a relevant field and strong modeling skills. The position offers an exciting research... 
    Scientific

    University of California

    Berkeley, CA
    2 days ago
  • A leading talent partner in executive search is seeking an experienced Mechanical Engineer in California. The ideal candidate will design and build complex robotic systems and contribute significantly from the product lifecycle's inception. Candidates should have a strong... 

    HMBL

    Emeryville, CA
    1 day ago
  • $128.69k - $194.96k

     ...32 Executive Office: Operations Cost Center: Vehicle Engineering Opening Date: 03/17/2026 Closing Date: 6/19/2026 11:5...  ...auxiliary power supply systems, and other electrical/electronic, mechanical, electromechanical, pneumatic, and hydraulic systems and... 
    Full time
    Contract work
    Temporary work
    Work experience placement
    Work at office
    Local area
    Visa sponsorship
    Flexible hours

    BARTCA

    Oakland, CA
    3 days ago
  • TERRANOVA in Berkeley, California, seeks a Senior Mechanical Engineer to lead mechanical design for large-scale robotic systems. You will manage projects from concept to field deployment, working in demanding environments. The role requires 5+ years of experience in hardware... 

    TERRANOVA

    Berkeley, CA
    4 days ago
  •  ...doctoral degree and 2-3 years of relevant MSL experience, including expertise in the Rare Disease sector. Responsibilities include maintaining scientific relationships, supporting clinical research, and delivering information on Ipsen’s therapies. #J-18808-Ljbffr Ipsen Group
    Scientific

    Ipsen Group

    Berkeley, CA
    1 day ago
  • $50 - $60 per hour

     ...individual with deep hands-on experience in a variety of analytical instrumentation and techniques, and a strong understanding of the regulatory...  ...~ BS or MS in Chemistry, Analytical Chemistry, or a related scientific field. ~5-10 years of hands-on experience in an... 
    Scientific

    Astrix Inc

    Oakland, CA
    4 days ago
  • $35 - $50 per hour

     ...degree OR 4-8 years hands-on GMP experience Upstream equipment proficiency (bioreactors, harvest filtration, sensors) Precise, collaborative, and quality-driven Send your resume to ****@*****.*** and reference Job #19795 . #J-18808-Ljbffr Scientific Search
    Scientific

    Scientific Search

    Emeryville, CA
    1 day ago
  •  ...Group is seeking a Medical Science Liaison for the South Region (TX, MO, LA, OK, AR) to engage with healthcare leaders and provide scientific insights. The ideal candidate will leverage expertise in migraine and headache treatment while demonstrating excellent project... 
    Scientific

    Ipsen Group

    Berkeley, CA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Mechanical Engineer, Scientific Instrumentation. Be the first to apply!