Principal Investigator (PI)

Job Description

Job Description

Job Title: Principal Investigator (PI)

Job Description

This Principal Investigator (PI) opportunity allows practicing physicians to integrate clinical research into their existing medical practice through a partnership model rather than a traditional full-time or salaried role. The PI will conduct and oversee clinical trials within their own practice setting while leveraging centralized regulatory, operational, and infrastructure support. This role offers a way to expand patient care options, contribute to medical advancement, and generate additional revenue through research participation without incurring upfront costs.

Responsibilities

• Conduct and oversee clinical trials within an existing medical practice, ensuring high standards of clinical care and data integrity.
• Collaborate closely with centralized regulatory and operational teams to initiate, manage, and complete clinical studies efficiently.
• Ensure strict compliance with study protocols, Good Clinical Practice (GCP), and applicable regulatory requirements throughout the trial lifecycle.
• Engage and educate established patient populations to promote appropriate trial participation and retention.
• Integrate research activities into routine clinical workflows while maintaining quality of care and patient safety.
• Provide medical leadership and oversight to the research team, including sub‑investigators such as nurse practitioners, physician assistants, or additional physicians when available.
• Review and interpret clinical data related to study subjects and communicate findings as required by study sponsors and regulatory bodies.
• Participate in study start-up activities, including site qualification, feasibility assessments, and protocol review as needed.

Essential Skills

• Medical degree (MD or DO) with an active medical practice.
• Board certification in a relevant medical specialty.
• Established patient population within the existing practice (required).
• Strong interest in participating in clinical research and integrating trials into routine clinical care.
• Ability to ensure compliance with study protocols and regulatory requirements.
• Capability to engage and communicate effectively with patients about clinical trial participation.
• Willingness to collaborate with centralized regulatory and operational teams.
• Commitment to maintaining high standards of clinical quality, ethics, and patient safety in a research setting.

Additional Skills & Qualifications

• Experience or clinical focus in central nervous system (CNS) disorders, cardiometabolic conditions, or dermatology.
• Prior clinical research experience, such as serving as a sub‑investigator or primary investigator (preferred but not required).
• Access to sub‑investigators, including nurse practitioners, physician assistants, or additional physicians within the practice.
• Familiarity with Good Clinical Practice (GCP) principles and clinical trial operations.
• Strong organizational skills to integrate research activities into existing practice workflows.
• Interest in expanding practice services and contributing to medical innovation through clinical trials.

Work Environment

The Principal Investigator conducts clinical research within their own active medical practice, embedding trial activities into the existing clinical environment. The practice benefits from externally provided equipment, regulatory support, operational resources, and study infrastructure, allowing research to be integrated without upfront costs. The PI collaborates with centralized teams that handle regulatory and operational functions, creating a structured and supported research setting. Clinical trials are conducted during the practice’s normal operating hours, aligning with existing patient schedules and workflows. The environment is professional and patient-centered, focused on delivering high-quality clinical care while generating robust research data and offering patients access to clinical trial opportunities.

This is a Permanent position based out of Austin, TX.

The pay range for this position is $200000.00 - $300000.00/yr.

Health insurance PTO Retirement plans

This is a fully onsite position in Austin,TX.

This position is anticipated to close on Jul 31, 2026.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email View email address on ziprecruiter.com for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.