Senior Manager, Research Informatics

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.The Opportunity:We are seeking a Senior Manager, Research Informatics to lead the strategy, development, and evolution of research informatics capabilities that accelerate Discovery Research. In this role, you will partner closely with scientific teams, computational scientists, and technology teams to define and deliver scalable digital solutions that transform how scientific data is captured, managed, analyzed, and leveraged across the research organization.You will lead initiatives to modernize research workflows by driving standardization, automation, expanding the adoption of enterprise platforms over standalone applications, and seamless integration across the research informatics ecosystem. By establishing scalable data frameworks, governance, and best practices, you will enable high-quality, traceable, and reusable scientific data that supports operational excellence, advanced analytics, and AI-enabled discovery. In this role you will be responsible for:Develop and execute the research informatics strategy to support scalable, efficient, high-quality workflows across Discovery Research.Partner with scientific, computational, and technology teams to align research priorities with informatics capabilities and technology roadmaps.Lead the design, governance, and lifecycle management of research data models, templates, workflows, and enterprise platforms, including Genedata Screener and Benchling.Automate and optimize data capture, assay analysis, reporting, and system integrations to improve efficiency, reproducibility, and data integrity.Establish standards and best practices for data management, metadata, workflow design, system configuration, and application lifecycle management.Build partnerships with scientists, computational teams, IT, vendors, and external collaborators to deliver high-impact informatics solutions.Prioritize application enhancements, support needs, and operational improvements to maintain strong service levels and user satisfaction.Drive user adoption through clear communication, training, change management, and stakeholder engagement.Assess emerging technologies, including AI-enabled platforms and advanced analytics, and define implementation strategies that improve scientific productivity.Required Skills, Experience and Education:Bachelor’s degree in a scientific, computational, or related field; advanced degree preferred.7 – 9 years of experience leading research informatics, scientific applications, or laboratory information management initiatives in biotech, pharmaceutical, or research settings.Experience with Assay Management platforms such as Genedata Screener, IDBS ActivityBase or Revvity Signals.Strong understanding of discovery research workflows, scientific data management, assay informatics, laboratory operations, and research data lifecycle management.Experience implementing, optimizing, and governing enterprise scientific platforms and informatics ecosystems.Proven ability to translate scientific and business needs into scalable technology solutions and long-term roadmaps.Experience leading cross-functional programs with scientists, software engineers, and external vendors.Working knowledge of workflow automation, systems integration, data standards, SQL, Python, and modern data integration approaches.Excellent communication, leadership, and executive presentation skills, with the ability to influence technical and scientific stakeholders.Demonstrated people leadership, coaching, and organizational development experience.Preferred SkillsExperience with Genedata Screener, Genedata Expressionist, Benchling, D360, Mosaic, or similar scientific informatics platforms.Experience supporting high-throughput screening, assay development, translational research, and discovery research teams.Knowledge of APIs, data pipelines, cloud-based research platforms, and enterprise integration architectures.Experience establishing research data governance, FAIR data principles, metadata standards, and reusable data frameworks.Experience developing informatics capabilities that support machine learning, AI-enabled workflows, or advanced analytics.Familiarity with resource planning, roadmap planning, vendor management, software licensing, and budgets. #LI-Hybrid #LI-YG1The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact View email address on click.appcast.io Pay Salary Range$164,000—$205,000 USDWe are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to View email address on click.appcast.io so we can share these impersonations with our IT team for tracking and awareness.