Sr. Principal Instrument Replacement Lead
$131.5kWaters Corporation
Overview Our Enterprise Transformation team is on a mission to improve business outcomes and employee experiences by driving step-change improvements in critical enterprise processes, and the technology and analytics supporting these.As a Sr. Principal, Lifecycle Program Lead, you will be responsible for delivering transformative improvements in enterprise Instrument Replacement capabilities, defining and scaling a consistent, data driven approach to managing instrument lifecycle replacement across business units, regions, and commercial motions. This role is accountable for end‑to‑end replacement excellence, supporting the commercial teams with installed base intelligence, replacement strategy and playbooks to improve commercial execution, governance model, and value realization.Partnering with global sales leadership, commercial excellence, finance, IT, and operations, the desired business outcomes include translating lifecycle strategy into repeatable operating models that improve revenue retention, revenue growth and customer loyalty. Responsibilities Enterprise Instrument Replacement strategyCollaborate with commercial leadership and functional SMEs in the definition of the enterprise instrument replacement strategy, ensuring a consistent, scalable approach across regions, product lines, and customer segmentsLead gap analysis, future-state model for replacement timing logic, segmentation, and prioritization frameworks anchored in installed base health, service signals, technology evolution, and customer valueFacilitate cross-functional working sessions to define clear principles for repair vs. replace, upgrade pathways, and trade‑in / migration models ensuring consistency while allowing business unit flexibilityEnd‑to‑End Lifecycle model designCollaborate with commercial leadershipand functional SMEs to design and support governing the future‑state replacement operating models, including: Installed base intelligence and lifecycle triggersCommercial plays and GTM motionsPricing guidance Ensure replacement programs are simple to understand, easy to deploy, and measurable, enabling effective adoption by business unitsCross‑Functional Leadership & GovernanceLead cross‑functional collaboration across Sales, Service, Commercial Excellence, Sales, Service, Product Management, Finance, IT, and AnalyticsFacilitate executive alignment and decision making by clearly articulating trade‑offs, value cases, and risks Define success metrics, KPIs, and partner with stakeholders to support governance, operating cadence for instrument replacement excellenceDigital, Data & Analytics EnablementPartner with the Commercial Operations and Customer 360 teams to: Ensure accurate and actionable installed base visibilityEmbed lifecycle and replacement triggers into CRM and analytics platformsEnable consistent tracking of replacement opportunities, conversion, and value realizationValue Realization & Continuous ImprovementDefine and track enterprise‑level impact of instrument replacement initiatives on: Revenue retention and growthMargin and asset productivityCustomer experience and loyaltyIdentify systemic bottlenecks and improvement opportunities, partnering with business units to address them Scale best practices globally while enabling regional and segment‑specific execution flexibility Qualifications Bachelor’s degree in business, Engineering, Economics, or a related field12+ years of experience in lifecycle management, commercial excellence, sales operations, service operations, or enterprise transformationProven experience leading complex, cross‑functional programs in a global, multi‑BU environmentStrong understanding of: Installed base management and asset lifecycle conceptsCommercial motions supporting replacement, upgrades, and renewalsSales and service operating modelsExperience working with CRM, installed base, and analytics platforms (e.g., Salesforce or similar)Demonstrated ability to influence without authority and drive alignment across senior stakeholdersStrong analytical mindset with the ability to translate strategy into executionLean / continuous improvement experience a plusResults‑oriented, with a strong sense of ownership and urgency Company Description Waters Corporation (NYSE:WAT) is a global leader in life sciences and diagnostics, dedicated to accelerating the benefits of pioneering science through analytical technologies, informatics, and service. With a focus on regulated, high-volume testing environments, our innovative portfolio harnesses deep scientific expertise across chemistry, physics, and biology. We collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance. Through a shared culture of relentless innovation, our passionate team of ~16,000 colleagues turn scientific challenges into breakthroughs that improve lives worldwide. Diversity and inclusion are fundamental to our core values at Waters Corporation. It benefits our employees, our products, our customers and our community. Waters complies with all applicable federal, state, and local laws. Qualified applicants are considered without regard to sex, race, color, ancestry, national origin, citizenship status, religion, age, marital status (including civil unions), military service, veteran status, pregnancy (including childbirth and related medical conditions), genetic information, sexual orientation, gender identity, legally recognized disability, domestic violence victim status, or any other characteristic protected by law. Waters is proud to be an equal opportunity workplace and is an affirmative action employer. All hiring decisions are based solely on qualifications, merit, and business needs at the time. Key Words #LI-Hybrid#Instrument replacement# instrument placement#lifecycle program, Job SummaryReq. #: 26223Job Family: PM - Project ManagementLocation: US-MA-Milford | US-CA-Milpitas | US-DE-New CastlePay Range Minimum: USD $131,500.00Pay Range Maximum: USD $219,000.00
- Waters Corporation is seeking a Sr. Principal, Lifecycle Program Lead to enhance lifecycle replacement capabilities across business units. This role focuses on defining and implementing instrument replacement strategies, ensuring a streamlined and effective approach while...Suggested
- ...Scorpion Therapeutics seeks a Senior Principal Biostatistical Programmer to lead data processing and analysis for Phase I–III clinical trials in a biopharma setting. You will generate analysis datasets using SAS, ensure CDISC compliance, develop macros, validate outputs...PrincipalSenior
- Incyte, a global biopharmaceutical company headquartered in Wilmington, Delaware, seeks a statistical expert to lead data processing and analysis for Phase I-III trials. The role emphasizes independent work, leadership of project teams, and collaboration across cross-functional...PrincipalSenior
- Incyte Corporation in Wilmington, Delaware seeks a senior statistician to lead statistical activities across Phase I-III trials. You will process clinical data for analyses, write SAPs, and contribute to study reports, ensuring high data quality and regulatory compliance...PrincipalSenior
- ...influence colleagues across our global network, drawing on both your own domain knowledge, as well as the cross-functional team. You will lead, develop, test, deploy, and drive adoption of inventory optimization levers realizing value.ResponsibilitiesSpecify program approach...PrincipalSeniorLocal areaWorldwide
- Title:Sr. Principal Piping Designer - CATS & SPECSAt KBR, We Deliver.KBR ISA (Integrated Solutions Americas) delivers integrated, end-to-end... ...related to catalog/specification development.Ability to lead corporate standardization initiatives and support multiple projects...PrincipalSeniorFull timeLocal areaFlexible hours
$169.6k - $254.4k
...customers and drives measurable, incremental impact for advertisers. We are seeking an experienced and highly skilled C14 Senior Analytics Lead to drive Audience Analytics & Targeting for the strategic Citi commerce function. This role will be critical in developing high...SeniorFull time- ...Handler to organize, sort, and redistribute incoming merchandise and maintain a safe, clean work environment. The role may back up Team Lead and Transportation when qualified, including driving responsibilities if a valid license and clean record apply. The position...Senior
$111.41k - $189.74k
WHAT IS THE OPPORTUNITY? The Fraud Prevention Senior Lead is responsible for leading delivery of large scale enterprise-wide fraud risk... ...in a high- paced, fluid environment is required. FRAUD PREVENTION SR LEAD WHAT WILL YOU DO? Lead cross-functional teams to develop and...SeniorRemote work- Incyte Corporation in Wilmington, Delaware, seeks a Senior Principal Investigator, Drug Product Process Development to lead DP process development, validation, and regulatory submissions. You will coordinate with internal and external teams, manage CDMOs, and ensure timelines...PrincipalSenior
- Incyte in Wilmington, DE seeks a Senior Principal Investigator in Drug Product Process Development to lead biologics DP development and validation efforts, and to manage CMC content for regulatory submissions. You will collaborate with internal teams and external CDMOs...PrincipalSenior
$124k
...seeking a strategic and results-driven Market Development Manager to lead the growth of our Environmental and Materials Science business... ...goals. The role spans the Waters total portfolio including instruments, consumables and application-specific offerings with a focus on...PrincipalLocal areaRemote workOverseas- ...Role: Senior Principal Biostatistical Programmer leading data processing and analysis for Phase I-III clinical trials in a biopharma setting. Responsibilities: perform SAS programming to generate analysis datasets, ensure CDISC compliance, develop macros, validate outputs...PrincipalSenior
- ...enjoy solving complex problems, improving how teams work, and raising the bar on quality, this role is built for you.Job summary As a Lead Business Systems Analyst in Marketing Data and Analytics, you will help design and deliver data-driven audience and targeting...Senior
- ...looking to hire a Mechanical Engineer of our New Castle office at the TA Instruments business unit. This is a phenomenal opportunity to gain real-world experience while working at the world's leading specialty measurement company in the field of materials...PrincipalWork at officeLocal areaWorldwide
$25 - $35 per hour
Zoom Drain Delaware is seeking an experienced Install Lead Technician to repair and replace drain and sewer pipes in residential homes and light commercial buildings. Youll lead field work, install pumps and fixtures, and ensure safety and quality on every site. The role...Hourly pay$26 per hour
Collectors is the leading creator of innovative technology that provides value-added services for collectors worldwide. We grade, authenticate... ...while maintaining meticulous attention to detail. You'll be instrumental in upholding our commitment that every item—regardless of...Hourly payWork experience placementRemote workWorldwideShift work- ...Lead Maintenance TechnicianGraver Technologies LLC is a part of the global industrial organization Marmon Holdings—which is backed... ...equipmentServices electronic equipment by checking, testing, and replacing faulty components, circuits, printed circuit boards and similar...Part timeFlexible hours
$22 - $28 per hour
...Castle Dental Associates in New Castle, Delaware is seeking a Lead Dental Assistant to support our clinical team with high-quality... ...Responsibilities include preparing treatment rooms, sterilizing instruments, taking X-rays, assisting dentists, educating patients on oral...Hourly pay- ...principles and contemporary product operating models, you will facilitate group discussions, promote effective decision-making, and lead collaborative activities that drive continuous improvement and high performance.In addition, you will help teams introduce new ways...SeniorShift work
- ...across product, application, data, and control stakeholders.As a Senior Associate - Data Quality Controls Governance and Reporting Lead at JPMorganChase within the Consumer and Community Banking Chief Data Office, you will support governance routines, reporting, and attestation...SeniorWork at office
- JPMorgan Chase is seeking a Quant Analytics Senior Associate to drive pricing analytics and research for credit card installment initiatives. You will apply advanced statistical methods, run experiments, and collaborate across Finance and Marketing to translate insights...Senior
$150k
...Automotive Lead Technician Join the World's Largest Midas Franchisee - Now Proudly Part of the Mavis Tire Family! Put your career into... .... Dismount, mount, rotate, and balance tires. Check fluids and replace worn automotive parts. What we're looking for Experience: At least...Weekly payFull timeWeekday work- ...Function) This role is responsible for processing clinical data required for statistical analysis of Phase I — III clinical trials and leading project teams. Essential Functions Of The Job (Key Responsibilities) Other responsibilities as required. Participate in the...PrincipalSeniorWork experience placementWork at officeLocal areaRelocation3 days per week
- ...Mesa Associates, Inc. in the Delaware/Newark area seeks a Principal Transmission Structural Engineer to lead analysis, design, and evaluation of transmission poles, towers, and foundations. You will guide technical work, mentor engineers, and ensure high-quality deliverables...SeniorRemote jobFlexible hours
- Hologic, Inc. in Newark, DE is seeking a Senior Metrology Technician to support engineering through dimensional inspection, development of inspection programs, MSA, and measurement system validation. You will read engineering drawings, select inspection methods, operate...Senior
- ...services, we are looking for people just like you. Join our team and help us develop game-changing, high-quality solutions. As a Senior Lead Architect at JPMorganChase within the Enterprise Risk Technology team of Corporate Sector you are an integral part of a team that...SeniorFor contractorsWork experience placement
$85.6k - $149.4k
About the RoleAs a Senior Technology Product Manager - GTM Enablement and Launch Lead, you will play a critical role in ensuring the successful planning, coordination, and execution of high‑impact product and go‑to‑market launches across a complex, enterprise B2B SaaS...SeniorFull timeWork at office- Smurfit WestRock invites a Senior Talent Acquisition Specialist to lead recruitment across multiple business segments for production, skilled trades, and salary non-exempt roles. You will design innovative TA strategies, partner with HR and leaders, and mentor peers while...Senior
- Incyte is seeking a Senior Manager, Biologics CMC Project Management to lead project management for biologics CMC programs across development stages. You will coordinate with Tech Ops, GBD leadership, and external partners to translate strategy into integrated development...Senior
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Sr. Principal Instrument Replacement Lead. Be the first to apply!
- senior level New Castle, DE
- senior implementation engineer New Castle, DE
- senior medical science liaison New Castle, DE
- senior application security New Castle, DE
- senior manager legal New Castle, DE
- senior activities New Castle, DE
- senior operations technician New Castle, DE
- srs New Castle, DE
- senior software engineer remote New Castle, DE
- senior implementation project manager New Castle, DE


