Principal Solution Architect

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com. As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function: Technology Enterprise Strategy & Security

Job Sub Function: Solution Architecture

Job Category: Scientific/Technology

All Job Posting Locations: Spring House, Pennsylvania, United States of America

Job Description

Principal Solution Architect We are seeking a Technical Solution Architect to join our Solution Architecture organization in Spring House, PA. This role will be instrumental in designing and delivering critical components of an end-to-end drug discovery engine, a pivotal initiative redefining how differentiated therapies are discovered. The architect will collaborate on a scalable, fit-for-purpose end-to-end technology stack supporting a Design–Make–Test–Learn (DMTL) closed-loop system, using AI, automation, and proprietary data to accelerate discovery outcomes. The impact of this role is significant and far-reaching, directly contributing to the transformation of drug discovery through advanced technology and data-driven innovation. By designing and enabling key components of the discovery engine!

Key Responsibilities

• Solution & Component Architecture. Design and govern modular solution architectures ensuring seamless data and workflow integration.
• Define integration patterns across platforms such as LIMS, SDMS, data platforms, and AI/ML systems
• Data & AI Architecture Enablement. Architect solutions enabling closed-loop data generation and feedback cycles across discovery workflows.
• Support design of AI-ready data pipelines, ensuring data quality, lineage, and accessibility and enable integration of AI/ML models and agentic tools into discovery processes
• Integration & Platform Engineering. Lead architecture for systems integration across lab automation, laboratory systems, and enterprise platforms, define patterns for event-driven workflows, orchestration, and observability in automated discovery pipelines.
• Collaborate with engineering teams (cloud, data, ML Ops) to deliver robust, scalable solutions
• Collaboration with Scientific & Engineering Teams. Partner with scientists, data engineers, AI researchers, and lab automation teams to translate scientific workflows into technical solutions.
• Co-design solutions that enable AI-augmented science and decision intelligence
• Governance, Security & Compliance. Ensure architectures align with cybersecurity, data governance, and regulatory standards. Embed secure-by-design principles, particularly in the context of AI and sensitive discovery data

Required Qualifications

• Experience: 5+ years in solution architecture, platform architecture, or systems integration
• Proven experience delivering large, complex, distributed, data-driven platforms
• Experience in life sciences / pharma R&D environments (preferred)

Technical Expertise

• Strong background in: Using GenAI tools to facilitate and deliver the architecture design
• Cloud-native architectures and distributed systems
• API-led and event-driven integration patterns
• Data platforms (e.g., Snowflake or equivalent AI-ready data systems)

Familiarity with

• AI/ML platforms and MLOps ecosystems
• Laboratory systems (LIMS, SDMS) and lab automation environments
• Data engineering and ingestion pipelines

Domain Knowledge (Preferred)

Understanding of drug discovery workflows (Design–Make–Test–Learn) Awareness of automation in laboratory environments and data generation pipelines

Key Competencies

The candidate demonstrates strong systems thinking, with the ability to design solutions across complex and highly interconnected domains. They bring deep expertise in abstraction and modular design, enabling the creation of scalable, component-level architectures that integrate seamlessly into broader platforms. The role requires excellent engagement skills, fostering effective collaboration across scientific and technical teams to translate complex requirements into actionable solutions. Appetite for innovation is essential, with comfort in working with emerging AI and automation technologies, combined with a clear execution focus to deliver high-impact results within bold timelines.

Required Skills

Required Skills: Preferred Skills: Change Management, Coaching, Consulting, Critical Thinking, Emerging Technologies, Enterprise IT Governance, Information Security Management System (ISMS), Information Technology Strategies, Information Technology Trends, IT Architecture, Organizing, Presentation Design, Product Configuration, Project Reporting, Report Writing, Requirements Analysis, Solution Architecture, Technical Credibility At Johnson & Johnson,we believe health is everything.

What we offer:

The opportunity to work on high-impact initiatives in a world-class healthcare organization, improving experiences for patients, customers, and colleagues. A collaborative, supportive environment where your architecture skill and curiosity are valued. Bring your architecture craftsmanship to a mission that matters and help us build technology and services that improve care for patients and customers across the world.

Johnson & Johnson is an Equal Opportunity Employer.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please contact us via or contact AskGS to be directed to your accommodation resource.

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