Senior Manager, HR Operations and Systems
$128k - $176kFlagship Pioneering
Senior Manager, HR Operations and Systems Cambridge, MA USA Position Overview Flagship Pioneering is seeking a Senior Manager, HR Operations & Systems to own and evolve our HR systems ecosystem, with primary responsibility for UKG and broad oversight of platforms including Greenhouse and other HR technologies. This role will drive day‑to‑day administration, governance, integrations, and future‑state strategy of HR systems to ensure compliance, enable scalable service delivery, strengthen data integrity, and support a seamless employee experience across the lifecycle. Reporting to the Associate Director, HR Operations & Analytics, this leader will partner closely with HR, Legal, Payroll, Finance, and Enterprise Applications / IT to design system‑enabled HR operations that are scalable, well‑governed, and built for growth. Role Summary The Senior Manager, HR Operations & Systems will serve as the business owner for Flagship’s HR systems ecosystem within HR Operations, with primary responsibility for the strategy, administration, optimization, and operational enablement of core HR platforms, including UKG, Greenhouse, and other HR technologies across the employee lifecycle. Reporting to the Associate Director, HR Operations & Analytics, this role will partner closely with HR Operations, Talent, Total Rewards, Learning & Culture, Legal, Payroll, Finance, People Analytics, and Enterprise Applications / IT to ensure systems support the HR function in a scalable, compliant, and analytically sound way. This leader will help stitch together the HR systems landscape through thoughtful integrations, controls, documentation, and future‑state HR tech strategy, while acting as a subject matter expert to IT for implementation and technical design. Key Responsibilities Serve as the primary HR business owner for HR systems, with deep ownership of UKG and operational oversight of other HR and talent platforms such as Greenhouse, TalentWall, Crosschq, LinkedIn Recruiter, Pequity, and future tools. Manage day‑to‑day administration of HR systems, including configuration, permissions, security roles, workflows, testing, issue resolution, release support, and operational documentation. Ensure HR systems are structured and maintained to support scalable service delivery, consistent HR operations, and strong user experience across the employee lifecycle. Maintain system standards, field logic, process flows, and governance documentation to improve consistency and reduce operational ambiguity. Architect HR systems and processes from an operational perspective, ensuring systems support onboarding, transfers, promotions, offboarding, compliance requirements, and service delivery across the employee lifecycle. Design and optimize integrations across the HR systems landscape, including key connections such as UKG‑ADP and Greenhouse‑UKG, to improve data flow, reduce manual work, and strengthen downstream reporting and controls. Partner with Enterprise Applications / IT to define technical requirements, integration priorities, testing strategy, and implementation needs; serve as the HR SME for system changes and implementations while IT owns technical implementation and vendor management. Be sufficiently hands‑on and technically fluent to configure systems directly where appropriate and to effectively guide or direct technical work when builds are completed by IT or other partners. Identify automation opportunities and future‑state improvements across HR systems to improve scalability, reduce friction, and support evolving business needs. Partner with HR Operations teammates, Legal, and other stakeholders to ensure systems are designed and configured to enable compliance, controls, audit readiness, and consistent execution of HR processes. Manage system‑enabled governance, including permissions, process controls, documentation logic, policy acknowledgement workflows, and audit‑supporting records. Help ensure systems support compliance execution across key areas such as documentation completeness, training administration, process controls, and employee record quality. Support the creation of scalable, system‑enabled HR ways of working by translating process requirements into governed workflows and operational logic. Partner closely with the People Analytics Manager to ensure HR systems are structured to support reliable reporting, meaningful analytics, and consistent data definitions. Improve data integrity across systems by aligning field design, ownership, process inputs, and integrations to reduce discrepancies and improve trust in people data. Ensure systems are built with analytics needs in mind, and conversely, help refine systems based on reporting and data‑quality insights. Support the broader HR function in strengthening compliance intelligence, scalable service delivery, and experience optimization through better system design and cleaner data. Build strong working relationships across HR, IT, Payroll, Finance, Legal, and other G&A partners to align systems strategy and operational delivery with business needs. Support change enablement through documentation, process clarity, and partnership with HR Operations and other HR team members; formal training delivery is not a core responsibility, but this role will help ensure systems and documentation are set up for successful adoption. Contribute to future‑state HR tech strategy, including evaluation of system opportunities and support for upcoming initiatives. What Success Looks Like HRIS and the broader HR systems landscape are well‑governed, well‑documented, and operationally effective. Core employee lifecycle processes are increasingly system‑enabled, scalable, and aligned across HR and cross‑functional partners. Permissions, controls, and integrations support stronger compliance execution and audit readiness. HR data is consistent, reliable, and usable across all company systems and platforms. The HR team and business partners experience smoother workflows, less manual work, and clearer operational processes. Flagship’s HR tech ecosystem is positioned for future growth, automation, and stronger decision support. Qualifications Strong hands‑on experience with enterprise HRIS administration and configuration; UKG experience strongly preferred, though deep equivalent HRIS experience may be considered. Experience owning or supporting enterprise HR systems across multiple HR process areas. Experience designing, managing, or supporting integrations between HRIS, ATS, payroll, and other people systems. Strong understanding of how systems support employee lifecycle operations, compliance controls, and scalable service delivery. Experience partnering closely with Enterprise Applications / IT teams on technical requirements, integrations, permissions, and implementation planning. Strong judgment and ability to manage confidential employee and organizational data responsibly. Strong written documentation and process‑design skills. Proven track record of independently driving operational improvements and cross‑functional initiatives. About Us We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. Salary and Benefits The salary range for this role is $128,000 - $176,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future. Privacy Notice for Applicants When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI‑assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of your personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact View email address on click.appcast.io. #J-18808-Ljbffr Flagship Pioneering
$145k - $160k
...Invest, Lux Capital, Regeneron Ventures, and RA Capital Management. The Senior Manager, HR Operations will serve as the operational backbone of the HR... ...the organization to build scalable people programs, systems, and processes that support all areas of the business...SeniorFlexible hours$145k - $180k
...and continuous improvement of HR operations with hands‑on delivery,... ...People Strategy functions, and senior leadership stakeholders. HR... ...documentation, including change management and communication. Lead HR... ...of people data across HR systems and records, in partnership...SeniorLocal areaTrial period$125k - $165k
The Opportunity As Senior Manager, Growth Operations & Systems, you’ll power Pearl Health’s commercial engine end-to-end—owning the systems, processes, and insights that drive growth from pipeline through long-term customer success, including territory planning, forecasting...SeniorContract workFlexible hoursShift work$149.6k - $166.22k
...development and implementation of transmission and distribution System Operations Training for CT, MA and NH. Supervise and oversee at least 2... ...Serves as liaison with System Operations Control Center management in CT, MA and NH to identify and address training needs....SeniorFor contractorsWork at office$128k - $176k
Flagship Pioneering is seeking a Senior Manager, HR Operations & Systems in Boston, MA. This role involves ownership of HR systems, notably UKG and Greenhouse, ensuring efficient and compliant HR operations across the employee lifecycle. The ideal candidate will have significant...Senior$149.6k - $166.22k
Eversource is seeking an individual to supervise the development and implementation of transmission and distribution System Operations Training in Massachusetts. The role involves overseeing staff, ensuring compliance with regulatory requirements, and assessing training...Senior$149.6k - $166.22k
...the creation and maintenance of transmission and distribution System Operations Procedures for CT, MA and NH. Supervise and oversee at least... ...CT, MA and NH.Liaise with System Operations Control Center management, adjacent Local Control Centers, Eversource and member...SeniorFor contractorsH1bWork at officeLocal area- Eversource Energy in Boston is seeking a Supervisor for System Operations Training. The role involves overseeing the development and implementation of training programs while managing a team. Applicants should have a bachelor's degree and considerable experience in electric...Senior
$138k - $144k
Jones Lang LaSalle Incorporated in Boston is seeking a Chief Engineer to oversee the efficient operation of all building systems while managing the engineering team. This role demands strong leadership abilities, and the ideal candidate will have over 7 years of experience...Senior$104k - $145.33k
...matter expert (SME) for AV technology and a manager of the AV team. In partnership with our... ...Desk team, the AV Team leads front-line operations and support of AV, working hand-in-hand... ...Oversee the daily operations of IT systems and equipment, ensuring they meet organizational...SeniorFor contractorsWork at officeLocal areaFlexible hours$150k - $250k
...A pioneering technology company in Cambridge is seeking a Senior / Principal Neuromorphic Systems Architect to design and prototype electronic architectures that integrate principles from neuroscience. The candidate should have a PhD in a relevant field and deep expertise...Senior- ...Principal Electrical Engineer. The ideal candidate will have over 10 years of experience, particularly in power electronics and embedded systems. You'll lead technical decisions, mentor engineers, and ensure the successful delivery of innovative consumer products. This role...Senior
- ...Senior Recruiter & People Operations Lead (Hybrid) Boston, MA At Wellist, we help... ...through every life moment and HR leaders can maximize the... ...Partner closely with hiring managers to align on role scope,... ...issues quickly Manage HR systems, documentation, and...Senior
- ...assist with the implementation of the Huron system, with the possibility of extension to a recurring role. The Training Manager will support the implementation of the... ...Executive Director of Research Intelligence and Operations and, ideally, will have experience in...Full timeFor contractors
- ...experience. The Opportunity We're seeking an operationally minded, detail-oriented, and mission-driven Senior Manager of Operations to lead business operations and... ...impact. You'll establish and maintain systems that support our research, evaluation, and policy...SeniorContract workWork at officeRemote workFlexible hours2 days per week
$171.78k - $190.34k
...designed to harness the body's natural protein recycling system to rapidly degrade disease-causing proteins, offering the... ...more information, please visit Job Summary As C4T's Senior Manager, IT Operations, you will oversee the day-to-day operation of our business...Senior- Trc Companies, Inc. is seeking a highly skilled Senior Project Manager in Boston, Massachusetts, to lead GIS system implementations for various utility projects. The ideal candidate will possess extensive experience in project management, excellent communication skills,...Senior
$134.8k - $146.2k
...Overview The Product Manager, HR People Operations is responsible for the strategic planning, functional optimization, and technical oversight... ...solutions. This position also plays a key role in system testing, change management, and user enablement to maximize...$150k - $170k
...corporate deck and other presentations here. About the Role Senior Manager, Legal Operations & Contracts As the Senior Manager, Legal... ...detail-oriented, highly organized, and proficient with systems and tools, with a solid understanding of corporate contracts...SeniorContract workWork at officeFlexible hours- Agios is seeking a Senior Project Manager for Patient Advocacy Operations. This role is pivotal in coordinating project management and operational support for... ..., and benefits focused on employee well-being and professional growth. #J-18808-Ljbffr Kinsley Power SystemsSeniorRemote jobFlexible hours
$138k - $207k
Training Senior Manager, GxP Operations Support page is loaded## Training Senior Manager, GxP Operations Supportlocations: Boston, MAtime type: Full... ...skills.* Proficiency in learning management systems (LMS) and e-learning tools.* Ability to analyze data and...SeniorSummer workFlexible hours- ...Senior Manager, Enterprise Systems Spyglass Partners LLC has over 20 years of experience as a nationwide staffing firm and is your ideal source for all your project-based temporary and direct-hire staffing needs. Spyglass Partners excels in placing contract and direct...SeniorContract workTemporary work
$170k - $200k
...transformative change in healthcare. As a Senior Product Manager on the Outreach team within Payer Data... ...to outreach to Providers via internal operations teams. This includes investments in... ...by a complete understanding of the systems your product touches and the ways in...Senior$136k - $204k
...Global Heme Cell and Gene Therapy (CGT) Operations team is at the forefront of innovation,... ....Position Summary:We are seeking a Senior Manager, CGT Operations Business Process to lead... ...stakeholders across commercial, quality, systems, and manufacturing, spearheading workstreams...SeniorSummer workRemote workFlexible hours2 days per week$140k - $175k
Summary The Senior Manager, Benefits & HRIS is responsible for leading and optimizing the company... ...employee data governance, and related HR operational processes across the organization.... ..., employee records, workflows, system security, access controls, confidentiality...SeniorWork at office$67.9k - $182.55k
...time. Position Summary TPA & Payer Solutions is seeking a Senior Manager, IT Operations - Technical Health to lead a technical health program focused... .... This role will lead efforts across operating system upgrades, database upgrades, software upgrades, security vulnerability...SeniorHourly payFull timeTemporary workWork experience placementLocal area$80k - $90k
Event Marketer is looking for a Senior Business Operations Manager based in Cambridge, Massachusetts. This role is essential to the Business Development team's operations, requiring strong organizational skills and CRM expertise, particularly in Salesforce. Candidates...Senior$131.04k - $196.55k
Senior Project Manager, Patient Advocacy Operations Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative... ...to detail and experience managing documentation, systems and workflows, ideally including SharePoint,...SeniorTemporary workRemote workWork from homeFlexible hours3 days per week$151k - $184k
Bicara Therapeutics is seeking a Senior Manager, Payroll and Equity in Boston to lead multi-state payroll processing for... ...compensation. Responsibilities include overseeing payroll system accuracy and collaborating with HR and finance. This hybrid position offers a salary...Senior- ...helping inventions find their way to the public. The Training Manager will support developing, implementing, and managing training guidance... ...and engage our community. Proficiency in Learning Management Systems (LMS) and other educational technologies. Ability to work with...For contractorsWork at office
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Manager, HR Operations and Systems. Be the first to apply!
- staffing supervisor Boston, MA
- director of people & culture Boston, MA
- human resources operations manager Boston, MA
- director of people operations Boston, MA
- hr director remote Boston, MA
- staff program manager Boston, MA
- senior hr manager Boston, MA
- staff services manager Boston, MA
- people manager Boston, MA
- hr manager Boston, MA

