Senior Metrology Specialist

Company Description Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real‑world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early‑stage cancer, and treatment selection for patients with advanced cancer. For more information, visitguardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook. Senior Metrology Specialist Within the Automation Service Engineering organization, the Senior Metrology Specialist is part of a dynamic team that supports all of the Guardant Health sites across California (Redwood City, Palo Alto, Union City and San Diego). The role is responsible for oversight, installation/qualification, calibration, maintenance, and repair of analytical and microbiology equipment. In this role, the candidate will help lead metrology strategies, advanced technical operations, and reliability initiatives to ensure measurement accuracy, regulatory compliance, and optimal asset performance across the organization. The Senior Metrology Specialist is a subject‑matter expert responsible for complex calibrations, system optimization, and leadership of the metrology program. This function drives innovation, standardization, and continuous improvement while mentoring staff and influencing cross‑functional decisions. Responsibilities Serve as an SME for metrology systems, calibration strategies, and measurement technologies. Perform and oversee complex calibrations, repairs, and equipment qualifications (IQ/OQ). Lead development and validation of advanced calibration methods and measurement system analysis. Analyze calibration and reliability data to identify trends, risks, and optimization opportunities. Design and implement reliability and proactive strategies to ensure equipment robustness (predictive maintenance, condition monitoring). Own and optimize CMMS/EAM systems, including asset strategies, KPIs, and reporting (e.g., MTBF, MTTR). Lead root‑cause investigations and implement robust corrective/preventive actions. Drive standardization of SOPs, work instructions, and engineering documentation. Act as technical lead during audits and regulatory inspections (e.g., ISO/IEC 17025, GMP, CAP, FDA). Manage vendor relationships, service contracts, and outsourced calibration programs. Lead the team in ownership and management of the temperature monitoring system. Lead capital projects including equipment selection, validation, and lifecycle planning. Provide mentorship, technical training, and career development for metrology staff. Collaborate with Automation Service Engineering, Quality, R&D, Manufacturing, and Facilities to align metrology with business objectives. Identify and implement cost‑saving initiatives and process improvements. Understand and adhere to internal and external regulations, procedures & policies. Perform other duties as assigned. Qualifications Bachelor’s degree in Metrology, Engineering, or related field (advanced degree preferred), or equivalent experience. 5+ years of relevant experience. Deep expertise in metrology principles, uncertainty analysis, and calibration systems. Advanced knowledge of ISO/IEC 17025, GMP, and regulatory compliance frameworks. Strong experience in reliability engineering and asset lifecycle management. Proficiency with CMMS/EAM systems and data analytics tools. Working knowledge of Viewpoint or similar environmental monitoring systems. Basic troubleshooting skills related to cold storage and other laboratory equipment. Demonstrated leadership, mentoring, and project management experience. Excellent analytical, problem‑solving, and communication skills. Experience applying 5S, Lean Manufacturing methodologies. Ability to influence cross‑functional stakeholders and drive strategic initiatives. Ability to take part in an on‑call rotation with after‑hours/weekend response as needed. Willingness to travel up to 30% as needed. AI & Digital Fluency Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI‑enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work. Hybrid Work Model Guardant has defined days for in‑person/onsite collaboration and work‑from‑home days for individual‑focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. Guardant’s work model provides flexibility for better work‑life balance while keeping teams connected to advance our science for our patients. Compensation Annualized base salary ranges: Redwood City, CA: $51 – $71k; Other U.S. locations: $44 – $60k. If the role is performed in Colorado, the pay range for this job is $46 – $64k. Additional Information Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time. Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long‑term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to View email address on click.appcast.io. A background screening, including criminal history, is required for this role. Guardant will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952). Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. All your information will be kept confidential according to EEO guidelines. To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants. Please visit our career page at: #J-18808-Ljbffr