Senior / Principal Technical Development Leader

Job Summary The Technical Development Leader (TDL) will lead Technical Development Teams (TDTs) in crafting and driving Chemistry, Manufacturing, and Control (CMC) strategies for clinical drug candidates from early human trials through product launch. Responsibilities Lead scientific and technical teams throughout the asset lifecycle, from preclinical development to product launch, ensuring the scientific integrity of the CMC strategy. Develop and implement multifaceted technology strategies essential for product success, including manufacturing processes, drug product and device configurations, supply chains, and regulatory submissions. Provide strategic insights and maintain regular updates to project teams, senior management, and governance committees, ensuring transparent and informed decision‑making. Design novel strategies for licensure of new modalities and efficient development of standard therapeutics, building new company capabilities. Represent Pharma Technical functions on asset/lifecycle teams and partner with various team leaders to align CMC strategy with broader company goals; act as a consultant to top executives as needed. Oversee manufacturing and delivery of clinical supplies, manage CMC development costs, and ensure adherence to timelines, milestones, and resource forecasts. Anticipate and resolve issues, developing contingency and risk mitigation plans. Serve as the primary decision maker for CMC development, investments, and risk management, employing effective decision‑making processes. Qualifications B.S./M.S./Ph.D. degree in chemistry, pharmaceutics, chemical engineering or a related field. 10–15+ years of experience in the pharmaceutical industry, with prior experience as a CMC team leader and strong technical knowledge of large‑molecule process and product development. Advanced understanding of the drug development process and a history of successful innovation, recognized as a thought leader in CMC/product development. Preferred Qualifications Demonstrated ability to handle complex, cross‑functional programs and innovate new ideas and approaches. Strong negotiation and decision‑making skills, with experience influencing senior stakeholders. Effective collaboration with team members and senior management, including experience working with third parties. Excellent verbal and written communication skills, with a history of influencing others in cross‑functional areas. Salary and Benefits The expected salary range for this position based on the primary location in South San Francisco, CA is $169,100 to $314,000 (Senior TDL) or $194,900 to $361,900 (Principal TDL). Actual pay will be determined based on experience, qualifications, geographic location, and other job‑related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This position also qualifies for the benefits detailed at the provided link. Relocation benefits are available for this posting. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company’s policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of protected veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing the Accommodations for Applicants form. #J-18808-Ljbffr F. Hoffmann-La Roche AG