Clinical Research Coordinator, Senior - Duke Cancer Institute

Clinical Research Coordinator, Senior - Duke Cancer Institute Work Arrangement: On-Site Location: Durham, NC, US, 27710 The Oncology Clinical Research Unit (CRU) within the Duke Cancer Institute is seeking a Clinical Research Coordinator Sr. to support the Leukemia/MPN Clinical Research Team (CRT) within the Hematologic Malignancies & Cellular Therapy (HMCT) Clinical Research Program. In this role, you will supervise a team of study coordinators and data managers/coordinators as part of your leadership of the day-to-day operations of a clinical research team conducting multiple, complex oncology clinical trials, including studies involving Investigational Products (IP). You will partner closely with Principal Investigators (PIs) and multidisciplinary teams to recruit, enroll, and support study participants while ensuring studies are conducted efficiently, ethically, and in compliance with institutional and regulatory requirements. This is an opportunity to take ownership of complex oncology trials, contribute to innovative research, and directly impact patient care and scientific advancement. Position Responsibilities Lead study operations and coordination for multiple complex oncology clinical trials, including participant recruitment, screening, enrollment, and retention strategies; evaluate processes and implement solutions to improve study performance Oversee study and site management activities , including regulatory compliance, maintenance of study documentation (regulatory binders, enrollment logs, Delegation of Authority logs), adverse event reporting, and participant registration in systems of record Collaborate with Principal Investigators and study teams to implement new studies, develop key documents such as Conflict of Interest (COI), Data Safety Monitoring Plans (DSMPs), and Research Data Security Plans (RDSPs), and troubleshoot study-related challenges Manage financial and operational aspects of trials , including tracking study milestones, documenting study payments and participant care expenses, supporting budget development, and assisting with study closeout activities Serve as the primary liaison between sponsors, PIs, and study personnel; communicate effectively and professionally while ensuring timely responses to inquiries and study needs Support data integrity and management , including use of Electronic Data Capture (EDC) systems, resolving sponsor queries, identifying data issues, and ensuring completeness, accuracy, and security of research data Lead and supervise research staff , including assigning work, managing performance, supporting professional development, conducting training, and ensuring compliance with protocols, SOPs, and regulatory requirements Foster a collaborative and high-performing team culture by promoting open communication, mentoring staff, setting measurable goals, and encouraging innovation and accountability Ensure ethical conduct of clinical research , educating staff and participants on the distinction between clinical care and research, and reinforcing adherence to professional guidelines, regulatory standards, and institutional policies Perform other related duties as assigned Minimum Qualifications Minimum of six years of research experience A Bachelor’s degree may substitute for two years of required experience Preferred Qualifications Oncology, hematology, or cellular therapy research experience Clinical trials coordination experience Experience in complex, multi-protocol research environments Other Requirements Basic Life Support (BLS) certification from the American Heart Association or a Duke-approved equivalent is required Must maintain required certifications, training, and compliance with SOPs, regulations, and protocol requirements Work Location Onsite. The work is performed on-site within the Oncology Clinical Research Unit. Benefits Your total compensation goes beyond the dollars on your paycheck. Duke provides comprehensive and competitive medical and dental care programs, generous retirement benefits, and a wide array of family-friendly and cultural programs to eligible team members. Learn more about Duke's benefits at hr.duke.edu/benefits. Equal Opportunity Employer Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy‑related conditions), sexual orientation, or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and reasonable accommodations can be requested with Duke Access and Accommodations Services (email: View email address on click.appcast.io; phone: View phone number on click.appcast.io). Affirmative Action Read more about Duke’s commitment to affirmative action and nondiscrimination at hr.duke.edu/eeo. #J-18808-Ljbffr