Principal Data Strategist, Real World Evidence
$106.8kBoston Scientific Corporation
Additional Location(s): US-MA-Marlborough; US-MN-Arden Hills
Diversity - Innovation - Caring - Global Collaboration - Winning Spirit - High Performance
At Boston Scientific, we’ll give you the opportunity to harness all that’s within you by working in teams of diverse and high-performing employees, tackling some of the most important health industry challenges. With access to the latest tools, information and training, we’ll help you in advancing your skills and career. Here, you’ll be supported in progressing – whatever your ambitions.
About the role:
The Principal Data Strategist, Real World Evidence (RWE) will lead enterprise real-world data (RWD) strategy and advanced analytics initiatives that support scalable, regulatory-aligned evidence generation across Boston Scientific. This role combines strategic leadership in data sourcing, vendor assessment, governance, and long-term data planning with deep expertise in real-world evidence, epidemiology, and data science.
This incumbent will be operating with a high degree of autonomy, this individual will shape fit-for-purpose RWD strategies, evaluate and operationalize external data assets, and lead advanced analytics initiatives using EHRs, claims, registries, and linked healthcare data. The role partners closely with Clinical, Medical Affairs, Regulatory, HEMA, IT, Biostatistics, Quality, and R&D stakeholders to advance both immediate evidence generation priorities and long-term data capabilities.
Work model, sponsorship, relocation:
At Boston Scientific, we value collaboration and synergy. This role follows a hybrid work model requiring employees to be in our local office at least three days per week at our Marlborough, MA or Arden Hills, MN office. Boston Scientific will not offer sponsorship or take over sponsorship of an employment visa for this position at this time. Relocation assistance is not available for this position at this time.
Your responsibilities will include:
Data Strategy & Vendor Management
- Support enterprise RWD strategy development and long-term data planning aligned with evidence generation priorities.
- Evaluate and operationalize external data assets including EHR, claims, registry, and emerging healthcare data sources.
- Lead vendor assessments and data source evaluations including quality, linkage feasibility, scalability, governance, and regulatory suitability.
- Partner cross-functionally to support data acquisition, governance, integration, and scalable analytics infrastructure.
- Provide strategic guidance on fit-for-purpose data selection, feasibility assessments, and analytic approaches.
Study Design & Execution
- Lead the design, development, and evaluation of RWE study protocols, including cohort definitions, endpoints, and analytic plans.
- Collaborate with KOLs and stakeholders to ensure robust analytical approaches and clinically meaningful outputs.
- Validate methodologies and results, ensuring transparency, reproducibility, and audit-readiness.
- Apply rigorous epidemiologic and statistical methods to address bias, confounding, and data limitations.
- Translate study findings into impactful reports and actionable insights to support evidence generation, value messaging, publications, regulatory submissions, and strategic decision-making.
- Ensure alignment of study design and execution with regulatory and methodological guidance.
- Oversee feasibility assessments, including data availability, fit-for-purpose evaluations, and study design optimization.
- Execute end-to-end RWE studies, from protocol development through analysis, interpretation, and dissemination of results.
Advanced Analytics, Communication & Leadership
- Develop advanced analytics solutions including predictive modeling, AI/ML methodologies, phenotyping, and NLP applications.
- Design dashboards and visualizations to communicate insights and support decision-making.
- Establish and promote best practices for data science, reproducible research, validation, and governance.
- Support publications, presentations, and regulatory-aligned scientific communications.
- Partner cross-functionally and mentor team members to advance organizational analytics and RWE capabilities.
Required qualifications:
- Minimum Bachelor’s degree or advanced degree in data science, biostatistics, epidemiology, computer science, health informatics, or a related field, or equivalent experience.
- Minimum of 5 years of experience with a Bachelor’s degree or 3 years with a Master’s degree in real-world evidence, healthcare analytics, data science, epidemiology, or related disciplines.
- Proven experience working with real-world healthcare data including electronic health records, claims, registries, and linked datasets.
- Demonstrated expertise in observational research methods, epidemiology, causal inference, and advanced statistical or machine learning methodologies.
- Proven proficiency in Python, R, SQL, and modern analytics environments.
- Experience evaluating external healthcare data assets and working with data vendors or strategic data partnerships.
- Strong communication and stakeholder management skills across technical and business audiences.
Preferred qualifications:
- Experience supporting regulatory-aligned evidence generation and health authority interactions.
- Experience leading enterprise or cross-functional data strategy initiatives.
- Experience with healthcare data linkage methodologies, tokenization, or distributed data environments.
- Experience applying AI/ML or NLP methodologies within healthcare or RWE settings.
- Experience working within a global or matrixed organization.
Requisition ID: 629425
Minimum Salary: $106800
Maximum Salary: $202900
The anticipated compensation listed above and the value of core and optional employee benefits offered by Boston Scientific (BSC) – see will vary based on actual location of the position and other pertinent factors considered in determining actual compensation for the role. Compensation will be commensurate with demonstrable level of experience and training, pertinent education including licensure and certifications, among other relevant business or organizational needs. At BSC, it is not typical for an individual to be hired near the bottom or top of the anticipated salary range listed above.
Compensation for non-exempt (hourly), non-sales roles may also include variable compensation from time to time (e.g., any overtime and shift differential) and annual bonus target (subject to plan eligibility and other requirements).
Compensation for exempt, non-sales roles may also include variable compensation, i.e., annual bonus target and long-term incentives (subject to plan eligibility and other requirements).
For MA positions: It is unlawful to require or administer a lie detector test for employment. Violators are subject to criminal penalties and civil liability.
Boston Scientific transforms lives through innovative medical technologies that improve the health of patients around the world. As a global medical technology leader for more than 45 years, we advance science for life by providing a broad range of high-performance solutions that address unmet patient needs and reduce the cost of healthcare. Our portfolio of devices and therapies helps physicians diagnose and treat complex cardiovascular, respiratory, digestive, oncological, neurological and urological diseases and conditions. Learn more at and follow us on LinkedIn .
Boston Scientific Corporation has been and will continue to be an equal opportunity employer. To ensure full implementation of its equal employment policy, the Company will continue to take steps to assure that recruitment, hiring, assignment, promotion, compensation, and all other personnel decisions are made and administered without regard to race, religion, color, national origin, citizenship, sex, sexual orientation, gender identity, gender expression, veteran status, age, mental or physical disability, genetic information or any other protected class.
Please be advised that certain US based positions, including without limitation field sales and service positions that call on hospitals and/or health care centers, require acceptable proof of COVID-19 vaccination status. Candidates will be notified during the interview and selection process if the role(s) for which they have applied require proof of vaccination as a condition of employment. Boston Scientific continues to evaluate its policies and protocols regarding the COVID-19 vaccine and will comply with all applicable state and federal law and healthcare credentialing requirements. As employees of the Company, you will be expected to meet the ongoing requirements for your roles, including any new requirements, should the Company’s policies or protocols change with regard to COVID-19 vaccination.
$196k - $269.5k
...Development & Agent Ops — Senior Principal Software Engineer Why This... ...to shaping how one of the world's largest technology companies... ...commitment that the work has real resources and real stakes.... ...infrastructure, solutions, and data management our customers need...PrincipalData$107.5k - $204.5k
...Principal Systems Engineer Are you passionate about turning innovative concepts into reality... ...to troubleshoot issues, perform data analysis, and implement solutions. Your... ...verification documentation in both simulated and real-world environments. Identify and resolve...PrincipalDataTemporary workWork experience placementLocal areaFlexible hours$132.4k - $251.6k
...Secret (DoD) clearance required prior to start date. At RTX, the world's largest aerospace and defense company, 185,000 great minds are... ...concepts to a SysML model Familiarity in digital ecosystems and data connectivity via digital threads Familiarity with data...PrincipalDataTemporary workWork experience placementRelocation packageFlexible hours$107.5k - $204.5k
...seeking a Senior Reliability Engineer. As a Principal Reliability, Availability, and... ...Operational Availability (Ao) Interpreting data and analyzing results Ensuring performance... ...a vision for a safer, more connected world. At RTX we value: Safety, Trust, Respect,...PrincipalDataTemporary workWork experience placementRelocation packageFlexible hours- ...and facilitate structured strategy/business planning workshops across all organizational levels Synthesize, analyze, and interpret data and insights from business units to support strategic planning Conduct research on market dynamics, industry trends, benchmarks, and...Data
$168k - $231k
Software Principal Engineer, Software Engineering The Software Engineering team delivers... ...and new products for a changing world. Working at the cutting edge, we design... ...that power infrastructure, solutions, and data management our customers need most. Our...PrincipalDataFull time$107.5k - $204.5k
...clearance required after day 1 At RTX, the world's largest aerospace and defense company,... ...a Senior Reliability Engineer. As a Principal Reliability, Availability, and Maintainability... ...Availability (Ao) Interpreting data and analyzing results Ensuring performance...PrincipalDataTemporary workWork experience placementWork at officeRemote workRelocation packageFlexible hours- ...) builds the products that power infrastructure, solutions, and data management our customers need most. Our teams design and develop... ...trust. When your products power critical infrastructure around the world, that responsibility matters.We move quickly toward the work...PrincipalData
$160k - $190k
...connected devices transmit sensor data to the SignalFire Cloud,... ...configure devices, and receive real-time alarms. The SignalFire... ...Programs Job Summary: The Principal Engineer & Team Lead for the... ..., communities, and the world around us. As part of our commitment...PrincipalDataImmediate startRemote workFlexible hours- ...Senior Principal Systems Security Engineer (Anti-Tamper/Program Protection) – P5 At Raytheon... ...that create a safer, more secure world. Raytheon is seeking a Senior Principal... ...designing, implementing, testing, and fielding real-time embedded security-oriented solutions...PrincipalRelocation package
$101k - $151k
...ingenuity of tomorrow. You Are You thrive on complex code and real‑world results. You see C++ as your toolkit for solving hard, meaningful... ...and experience in large codebases Solid grasp of algorithms, data structures, and heuristics Experience with formal verification...Data$106.8k
...employees experience every day. The Principal Manager, Email Performance owns the... ...execution—driving measurable impact through data-led decision-making, experimentation, and... ...improve the health of patients around the world. As a global medical technology leader...PrincipalDataHourly payWork at officeRelocationRelocation packageShift work3 days per week- ..., public registry, and real‑time compliance monitoring... ...scalable, secure, and world‑class. What You’ll Do... ...audit workflow tools, evidence collection, scoring/assessment... ...(VP Engineering, CTO, Principal Engineer). Proven... ...security best practices, data encryption, access...Data
- ...flexible at-home life optimizations. Learn More: We are seeking a Principal Cloud Software Engineer to provide deep technical leadership... ...and influence designs across compute, networking, identity, data, and observability layers Ensure architectural decisions...PrincipalDataWork experience placementWork at officeFlexible hours
- ...Principal Embedded Software Engineer This is your opportunity to join the Receiver/ Exciter & Processing Architecture (REPA) Department... ..., and performance with a vision for a safer, more connected world. At RTX we value: Safety, Trust, Respect, Accountability, Collaboration...PrincipalRelocation packageDay shift
- ...offers both technical and professional growth opportunities. Principal C++/Qt/QML Software Engineer The Principal C++/Qt/QML... ...decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us....PrincipalDataFull time
- ...We are trusted to deliver by some of the world’s best-known brands, including ITV, Rolls-... ...into the details. You get under the skin of real user needs and balance them with business... ...Synthesis - Independently synthesises complex data into clear, strategic insights and coaches...DataFull time
- ...Description WHO WE ARE RoslinCT is a world-leading cell and gene therapy contract development... .... ACCELERATING YOUR FUTURE The Principal, QA - Validation is responsible for... ...CFR Part 11 and Annex 11. Support site Data Integrity initiatives Support implementation...PrincipalDataContract workFlexible hours
- ...Principal Level Electrical Engineer The Radar Digital Products (RDP) Department at Raytheon is seeking an experienced Principal level... ...behaviors, and performance with a vision for a safer, more connected world. At RTX we value: Safety, Trust, Respect, Accountability,...PrincipalRelocation
- ...Principal Control Account Manager At RTX, the world's largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world's most complex problems. With our three market leading businesses, world-class...PrincipalRelocation packageFlexible hours
- ...Principal RF Design Engineer At Raytheon, the foundation of everything we do is rooted in our values and a higher calling – to help... ...solves tough, meaningful problems that create a safer, more secure world. Raytheon's Receiver/Exciter & Processing Architecture (REPA...PrincipalRelocationDay shift
- ...Our client, a leading Human Resources Services company, is looking for a Principal Data Analyst, Paid Media to join their team. This role is hybrid if local to the Framingham, MA area or remote for those outside the area. The Opportunity Join the Business Analytics team...PrincipalDataPermanent employmentLocal areaRemote work
$19 - $23.75 per hour
...A World-Class Team BJ’s Wholesale Club is powered by more than 30,000 team members who make a real impact every day. Whether you're stocking shelves, solving problems or shaping... ...thorough knowledge and utilization of business data. Lead through change. Model leadership...DataWeekly payFull timeFlexible hours$86.8k - $165.2k
...clearance required after day 1 At RTX, the world's largest aerospace and defense company, 1... ...Do: Code, test, and integrate C++ real-time signal processing algorithms or... ...ARM PL. Experience with DDS (Distributed Data Systems). Experience in C++20 or newer....DataTemporary workWork experience placementWork at officeRemote workRelocationFlexible hoursDay shift- ...Principal Mechanical Engineer At RTX, the world's largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world's most complex problems. With our three market leading businesses, world-class operations...PrincipalWork at officeRelocation packageFlexible hours
- ...awards And much more! Position Summary: The Real Estate Administrator is responsible for... ...Management database (Horizon) with accurate lease data. Track and obtain tenant insurance... ...important that our employees reflect the world we live in and the communities we serve. We...DataFull timeLive inWork at officeImmediate start
$150k - $205k
...professional growth opportunities. Principal System Engineer: At Full Spectrum... ...pathways. Mentor & Coach: Provide real-time guidance, training, and problem-solving... ...you would like more information about how your data is processed, please contact us....PrincipalData$132.4k - $251.6k
...Senior Principal Digital Electrical Engineer Collins Aerospace, an RTX company, is seeking a Senior Principal Digital Electrical Engineer... ...of something bigger? A team whose impact stretches across the world, and even beyond? At Collins Aerospace, our Mission Systems...PrincipalTemporary workWork experience placementWork at officeRemote workRelocation packageFlexible hours$250k - $300k
...Principal ID 2026-2464 Location US-MA-Natick Practice Thermal... ...create a safer, healthier, more sustainable world. For over five decades, we've connected the... ..., financial, and technical expertise to real-world challenges in energy markets,...PrincipalFull timeWork at officeFlexible hours- ...Sr Data Scientist This role will play a pivotal part in shaping the future of our analytics initiatives, leveraging your expertise... ...infrastructure and data science development platforms, with real world experience to help guide decisions about these tools. Excellent...DataWork experience placement
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Data Strategist, Real World Evidence. Be the first to apply!
- principal Marlborough, MA
- data analysis part time Marlborough, MA
- data Marlborough, MA
- data labeling Marlborough, MA
- data technician Marlborough, MA
- clinical data coordinator remote Marlborough, MA
- data visualization Marlborough, MA
- sap master data Marlborough, MA
- health data Marlborough, MA
- data collection researcher Marlborough, MA



