Principal Data Strategist, Real World Evidence
$106.8kBoston Scientific
Additional Location(s): US-MA-Marlborough; US-MN-Arden Hills
Diversity - Innovation - Caring - Global Collaboration - Winning Spirit - High Performance
At Boston Scientific, we’ll give you the opportunity to harness all that’s within you by working in teams of diverse and high-performing employees, tackling some of the most important health industry challenges. With access to the latest tools, information and training, we’ll help you in advancing your skills and career. Here, you’ll be supported in progressing – whatever your ambitions.
About the role:
The Principal Data Strategist, Real World Evidence (RWE) will lead enterprise real-world data (RWD) strategy and advanced analytics initiatives that support scalable, regulatory-aligned evidence generation across Boston Scientific. This role combines strategic leadership in data sourcing, vendor assessment, governance, and long-term data planning with deep expertise in real-world evidence, epidemiology, and data science.
This incumbent will be operating with a high degree of autonomy, this individual will shape fit-for-purpose RWD strategies, evaluate and operationalize external data assets, and lead advanced analytics initiatives using EHRs, claims, registries, and linked healthcare data. The role partners closely with Clinical, Medical Affairs, Regulatory, HEMA, IT, Biostatistics, Quality, and R&D stakeholders to advance both immediate evidence generation priorities and long-term data capabilities.
Work model, sponsorship, relocation:
At Boston Scientific, we value collaboration and synergy. This role follows a hybrid work model requiring employees to be in our local office at least three days per week at our Marlborough, MA or Arden Hills, MN office. Boston Scientific will not offer sponsorship or take over sponsorship of an employment visa for this position at this time. Relocation assistance is not available for this position at this time.
Your responsibilities will include:
Data Strategy & Vendor Management
- Support enterprise RWD strategy development and long-term data planning aligned with evidence generation priorities.
- Evaluate and operationalize external data assets including EHR, claims, registry, and emerging healthcare data sources.
- Lead vendor assessments and data source evaluations including quality, linkage feasibility, scalability, governance, and regulatory suitability.
- Partner cross-functionally to support data acquisition, governance, integration, and scalable analytics infrastructure.
- Provide strategic guidance on fit-for-purpose data selection, feasibility assessments, and analytic approaches.
Study Design & Execution
- Lead the design, development, and evaluation of RWE study protocols, including cohort definitions, endpoints, and analytic plans.
- Collaborate with KOLs and stakeholders to ensure robust analytical approaches and clinically meaningful outputs.
- Validate methodologies and results, ensuring transparency, reproducibility, and audit-readiness.
- Apply rigorous epidemiologic and statistical methods to address bias, confounding, and data limitations.
- Translate study findings into impactful reports and actionable insights to support evidence generation, value messaging, publications, regulatory submissions, and strategic decision-making.
- Ensure alignment of study design and execution with regulatory and methodological guidance.
- Oversee feasibility assessments, including data availability, fit-for-purpose evaluations, and study design optimization.
- Execute end-to-end RWE studies, from protocol development through analysis, interpretation, and dissemination of results.
Advanced Analytics, Communication & Leadership
- Develop advanced analytics solutions including predictive modeling, AI/ML methodologies, phenotyping, and NLP applications.
- Design dashboards and visualizations to communicate insights and support decision-making.
- Establish and promote best practices for data science, reproducible research, validation, and governance.
- Support publications, presentations, and regulatory-aligned scientific communications.
- Partner cross-functionally and mentor team members to advance organizational analytics and RWE capabilities.
Required qualifications:
- Minimum Bachelor’s degree or advanced degree in data science, biostatistics, epidemiology, computer science, health informatics, or a related field, or equivalent experience.
- Minimum of 5 years of experience with a Bachelor’s degree or 3 years with a Master’s degree in real-world evidence, healthcare analytics, data science, epidemiology, or related disciplines.
- Proven experience working with real-world healthcare data including electronic health records, claims, registries, and linked datasets.
- Demonstrated expertise in observational research methods, epidemiology, causal inference, and advanced statistical or machine learning methodologies.
- Proven proficiency in Python, R, SQL, and modern analytics environments.
- Experience evaluating external healthcare data assets and working with data vendors or strategic data partnerships.
- Strong communication and stakeholder management skills across technical and business audiences.
Preferred qualifications:
- Experience supporting regulatory-aligned evidence generation and health authority interactions.
- Experience leading enterprise or cross-functional data strategy initiatives.
- Experience with healthcare data linkage methodologies, tokenization, or distributed data environments.
- Experience applying AI/ML or NLP methodologies within healthcare or RWE settings.
- Experience working within a global or matrixed organization.
Requisition ID: 629425
Minimum Salary: $106800
Maximum Salary: $202900
The anticipated compensation listed above and the value of core and optional employee benefits offered by Boston Scientific (BSC) – see will vary based on actual location of the position and other pertinent factors considered in determining actual compensation for the role. Compensation will be commensurate with demonstrable level of experience and training, pertinent education including licensure and certifications, among other relevant business or organizational needs. At BSC, it is not typical for an individual to be hired near the bottom or top of the anticipated salary range listed above.
Compensation for non-exempt (hourly), non-sales roles may also include variable compensation from time to time (e.g., any overtime and shift differential) and annual bonus target (subject to plan eligibility and other requirements).
Compensation for exempt, non-sales roles may also include variable compensation, i.e., annual bonus target and long-term incentives (subject to plan eligibility and other requirements).
For MA positions: It is unlawful to require or administer a lie detector test for employment. Violators are subject to criminal penalties and civil liability.
Boston Scientific transforms lives through innovative medical technologies that improve the health of patients around the world. As a global medical technology leader for more than 45 years, we advance science for life by providing a broad range of high-performance solutions that address unmet patient needs and reduce the cost of healthcare. Our portfolio of devices and therapies helps physicians diagnose and treat complex cardiovascular, respiratory, digestive, oncological, neurological and urological diseases and conditions. Learn more at and follow us on LinkedIn .
Boston Scientific Corporation has been and will continue to be an equal opportunity employer. To ensure full implementation of its equal employment policy, the Company will continue to take steps to assure that recruitment, hiring, assignment, promotion, compensation, and all other personnel decisions are made and administered without regard to race, religion, color, national origin, citizenship, sex, sexual orientation, gender identity, gender expression, veteran status, age, mental or physical disability, genetic information or any other protected class.
Please be advised that certain US based positions, including without limitation field sales and service positions that call on hospitals and/or health care centers, require acceptable proof of COVID-19 vaccination status. Candidates will be notified during the interview and selection process if the role(s) for which they have applied require proof of vaccination as a condition of employment. Boston Scientific continues to evaluate its policies and protocols regarding the COVID-19 vaccine and will comply with all applicable state and federal law and healthcare credentialing requirements. As employees of the Company, you will be expected to meet the ongoing requirements for your roles, including any new requirements, should the Company’s policies or protocols change with regard to COVID-19 vaccination.
$132.4k - $251.6k
...that create a safer, more secure world. Raytheon is seeking a talented and motivated Senior Principal Systems Engineer to join our... ...to troubleshoot issues, perform data analysis, and implement solutions... ...in both simulated and real-world environments.Troubleshoot...PrincipalDataTemporary workWork experience placementWork at officeLocal areaRemote workFlexible hours- ...hands-on engineering leader to serve as Principal Data Engineer , building the governed data... ..., biomarker, safety, vendor, and real-world data Implement transfer monitoring,... ...dictionaries, lineage, procedures, and validation evidence Develop governed datasets for...PrincipalData
$196k - $269.5k
...Development & Agent Ops — Senior Principal Software EngineerWhy This... ...contribute to shaping how one of the world's largest technology companies... ...commitment that the work has real resources and real stakes.... ...infrastructure, solutions, and data management our customers need...PrincipalData$103k - $131.5k
...A World-Class Team BJ’s Wholesale Club is powered by more than 30,000 team members who make a real impact every day. Whether you're stocking shelves, solving problems or shaping strategy... ...forecasting within categories using data-driven analytics, trend insights, and business...PrincipalDataWeekly payWork at officeRemote workMonday to FridayFlexible hours$107.5k - $204.5k
...prior to start dateAt RTX, the world's largest aerospace and... ...product portfolio.We are seeking a Principal Hardware Integration, Analysis... ...Band systems.Dig into RF and IQ data to find the root cause of hard... ...'t obvious and the stakes are real.What You Will Do:Perform...PrincipalDataTemporary workWork experience placementInterim roleWork at officeRemote workRelocationFlexible hours$107.5k - $204.5k
...engineering career.At RTX, the world’s largest aerospace and... ...team discipline is seeking a Principal Systems Engineer to support important... ...through lots of troubleshooting and data analysis. You'll be expected... ...in both simulated and real-world environments. Troubleshoot...PrincipalDataTemporary workWork experience placementInterim roleWork at officeLocal areaRemote workRelocation packageFlexible hours$107.5k - $204.5k
...is required prior to start dateAt RTX, the world's largest aerospace and defense company, 1... ...on a variety of different tasks including real-time software development, application software development, test and verification, data analysis, software tools development, and...PrincipalDataTemporary workWork experience placementInterim roleWork at officeLocal areaRemote workRelocationFlexible hours$107.5k - $204.5k
...career. \n \n At RTX, the world’s largest aerospace and... ...team discipline is seeking a Principal Systems Engineer to support important... ...lots of troubleshooting and data analysis. You'll be expected to... ...in both simulated and real-world environments. \n Troubleshoot...PrincipalDataTemporary workWork experience placementInterim roleWork at officeLocal areaRemote workRelocation packageFlexible hours$160k - $190k
...connected devices transmit sensor data to the SignalFire Cloud,... ...configure devices, and receive real-time alarms. The SignalFire... ...Programs Job Summary: The Principal Engineer & Team Lead for the... ..., communities, and the world around us. As part of our commitment...PrincipalDataImmediate startRemote workFlexible hours$145.46k - $207.8k
...com. Are you driven to make a real difference in the lives of patients... ...impact.Purpose & Scope The Principal Scientist, Ophthalmology... ...incumbent will generate high-quality data that inform strategic program... ...' lives worldwide. Real-world patient impact: Contribute to...PrincipalDataContract workWorldwide- ...Principal Systems EngineerRaytheon is seeking a talented and motivated Principal Systems Engineer... ...numerical analysis of radar performance data.Analysis tool development in support of... ...a vision for a safer, more connected world. At RTX we value: Safety, Trust, Respect,...PrincipalDataRelocation package
$132.4k - $251.6k
...required prior to start dateAt RTX, the world's largest aerospace and defense company,... ...products.We have an opportunity for a Senior Principal RF Design Engineer who is seeking to... ...card assembly and fabricationHigh speed data converter test / characterizationLow Noise...PrincipalDataTemporary workWork experience placementInterim roleWork at officeRemote workRelocationFlexible hoursDay shift- ...our employees experience every day.As a Principal Clinical Quality Assurance Specialist, you... ...accuracy, integrity and quality of clinical data generated during clinical investigations.... ...the health of patients around the world. As a global medical technology leader for...PrincipalDataHourly payLocal areaRelocationShift work3 days per week
$85 per hour
...generation directly into the migrated pipelines so that CRA/CE technical evidence is produced as a by-product of day-to-day engineering. Design... ...trees / MITRE ATT&CK for ICS where appropriate), producing data-flow diagrams with trust boundaries during the requirements/...PrincipalDataHourly payTemporary workFor contractorsWork visa$122.25k - $176.58k
Job Title: Principal Scientist - CMC StatisticianLocation: Framingham,... ...pharmaceutical products, the R&D Data Sciences department and more... ...for several CMC sites in the world.Join the engine of Sanofi’s mission... ...design studies that reflect real-world needs.Help improve the...PrincipalDataFull timeLocal area- ...our employees experience every day.As a Principal Product Analyst, you will play a critical... ...regulatory reporting processes, leveraging data analytics to identify risks and... ...improve the health of patients around the world. As a global medical technology leader for...PrincipalDataHourly payWork at officeLocal areaRelocationRelocation packageShift work3 days per week
$86.8k - $165.2k
...Clearance Status: Not RequiredAt RTX, the world's largest aerospace and defense company,... ...Finance professional to assume the role of Principal Financial Analyst for the Qatar Early... ...and business acumenAnalyze key financial data that will enable sound program decision making...PrincipalDataContract workTemporary workWork experience placementWork at officeRemote workFlexible hours$122.25k - $176.58k
Job title: Principal Automation Software EngineerLocation: Framingham,... ...handling systems, and associated data workflows. Works closely with... ...millions of people around the world. Together, we chase the... ...turn complex challenges into real-world solutions.Advance your career...PrincipalDataFull time$107.5k - $204.5k
...problems that create a safer, more secure world.The Radar Digital Products (RDP) Department at Raytheon is seeking an experienced Principal level Electrical Engineer in the... ...in common computer hardware interface and data protocols such as RS-422, USB, PCIe, etc....PrincipalDataTemporary workWork experience placementWork at officeRemote workRelocationFlexible hours$107.5k - $204.5k
...solves tough, meaningful problems that create a safer, more secure world. The Radar Analog and Power Department is seeking electrical... ...within the bounds of a given schedule.Present reviews of technical data to program leadership, technical staff, and customer community....PrincipalDataTemporary workWork experience placementWork at officeRemote workRelocationFlexible hours$86.8k - $165.2k
...Not Required Security Clearance Status: Not RequiredAt RTX, the world largest aerospace and defense company, 185,000 great minds are... ...including Excel for financial analysis, forecasting, variance analysis, data tracking, and reporting; Word for financial documentation and...PrincipalDataContract workTemporary workWork experience placementWork at officeRemote workFlexible hours$107.5k - $204.5k
...meaningful problems that create a safer, more secure world. The Radar Analog and Power Department is seeking an experienced Principal Electrical Engineer with knowledge of... ...current, temperature) using electronic test and data acquisition equipment.Present reviews of technical...PrincipalDataTemporary workWork experience placementWork at officeRemote workRelocationFlexible hoursDay shift$107.5k - $204.5k
...issued security clearance is required prior to start dateAt RTX, the world's largest aerospace and defense company, 185,000 great minds are... ..., Project Configurator, ScriptRunner, and JSU Automation.Data Management and Reporting: Lead the design and maintenance of dashboards...PrincipalDataFull timeTemporary workWork experience placementInterim roleWork at officeLocal areaRemote workRelocationFlexible hours$107.5k - $204.5k
...aggression, creating a safer, more secure world. Join us and help shape the future of... ...Digital Products Department is seeking a Principal Electrical Engineer with strong COTS computing... ...processor bus analyzers, emulators, and data capture tools, etc.Collaborate in...PrincipalDataTemporary workWork experience placementWork at officeRemote workRelocationFlexible hours- ...is seeking an experienced software engineer to investigate and implement on-prem LLM and agentic AI workflows. The role focuses on real-time C++/CUDA signal processing for sensor systems on a distributed Linux backend. The position requires a STEM degree with 10+ years...Principal
$107.5k - $204.5k
...clearance required after day 1At RTX, the world's largest aerospace and defense company,... ....We have an immediate need for an onsite Principal Software Systems Quality Engineer (Compliance... ...- Ensure integrity of the technical data package. Identify, collect, and measure software...PrincipalDataTemporary workWork experience placementWork at officeLocal areaImmediate startRemote workRelocationMonday to FridayFlexible hours- ...Principal Embedded Software Engineer Newark, DE, United States Marlborough, MA, United... ...PFMEA); evaluate and develop process control data as applicable to component, subsystem,... ...experience designing and optimizing real-time, resource-constrained systems, including...PrincipalDataLocal area3 days per week
- Software Principal Engineer, Software Engineering The Software Engineering team delivers next... ...and new products for a changing world. Working at the cutting edge, we design... ...that power infrastructure, solutions, and data management our customers need most. Our teams...PrincipalData
$107.5k - $204.5k
...security clearance required on day 1 Senior Principal Network Engineer (P4) Raytheon Digital... ...that create a safer, more secure world. The Classified Infrastructure Services... ...High Performance Computing, and Storage & Data Protection. Join this high impact team as...PrincipalDataFull timeTemporary workWork experience placementWork at officeLocal areaRemote workRelocationFlexible hoursWeekend workAfternoon shift$176k - $242k
...that power infrastructure, solutions, and data management our customers need most. Our... ...power critical infrastructure around the world, that responsibility matters.We move quickly... ..., you'll find your place here.Senior Principal Hardware EngineerThe reputation of Dell Technologies...PrincipalDataWork at officeRelocation package
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Data Strategist, Real World Evidence. Be the first to apply!
- senior brand strategist Marlborough, MA
- senior principal cloud computing engineer Marlborough, MA
- principal Marlborough, MA
- senior principal scientist Marlborough, MA
- sap master data Marlborough, MA
- data network cabling Marlborough, MA
- data collection Marlborough, MA
- clinical data Marlborough, MA
- data recovery Marlborough, MA
- data analysis part time Marlborough, MA




