Senior Manager, Clinical Research

Job Description

Job Description

Company Description

Butterfly Network, Inc. (NYSE: BFLY) is driving a digital revolution in ultrasound imaging and sensing with its proprietary Ultrasound-on-Chip™ semiconductor technology and software solutions. Butterfly first proved its technology in the point-of-care ultrasound market – commercializing the world's first single-probe, whole-body portable ultrasound device, which is now on its best-selling, third-generation: Butterfly iQ3™. The Company combines its advanced hardware with cloud software and AI, an enterprise workflow solution (Compass AI™) and other offerings to drive adoption of affordable, accessible ultrasound. Butterfly also enables third-party development of imaging AI apps through Butterfly Garden™, its software development kit and AI partnership initiative.

In addition to its medical imaging products, Butterfly Embedded™ is the Company's Ultrasound-on-Chip™ licensing and co-development program designed to enable a new wave of ultrasound-enabled technologies across non-competitive healthcare markets and beyond. Through Butterfly Embedded™, partners can build and scale novel ultrasound applications powered by Butterfly's proprietary semiconductor chip and software platform. Butterfly's innovations have been recognized by Prix Galien USA, Fierce 50, TIME's Best Inventions and Fast Company's World Changing Ideas, among other achievements.

We're a team of bold thinkers, problem-solvers, and innovators ready to shape the future of medical imaging. Let's build something extraordinary together!

We are seeking an organized, detail-oriented Clinical Operations Manager to oversee the execution, compliance, and documentation of our clinical portfolios. In this role, you will not lead primary protocol design. Instead, you will act as the operational backbone of our clinical efforts. You will keep track of Investigator-Initiated Trials (IITs), manage rigorous verification and validation (V&V) paperwork, and draft Institutional Review Board (IRB) submissions. You will also manage one direct report (Clinical Coordinator) to ensure clinical projects hit timelines and meet regulatory standards.

Your core responsibilities will be:

• Trial Tracking & Investigator Support
• Serve as the primary operational point of contact for external clinicians managing Investigator-Initiated Trials (IITs).
• Maintain rigorous tracking systems for milestones, data collection timelines, and budget disbursements for all ongoing IITs.
• Ensure external investigators comply with study agreements, safety reporting, and data publication timelines.

• Regulatory, IRB & Compliance Documentation
• Lead the drafting, formatting, and submission of Institutional Review Board (IRB) applications, amendments, and annual renewals.
• Cross-functionally collaborate with Engineering and Quality Assurance (QA) teams to organize, maintain, and audit internal Verification and Validation (V&V) documentation.
• Ensure all trial master files (TMF) and study documentation are audit-ready and compliant with FDA, ISO 14155, and Good Clinical Practice (GCP) guidelines.

• Leadership & Operations
• Manage, mentor, and delegate tasks to a Clinical Coordinator, ensuring efficient daily operational workflows.
• Keep internal stakeholders (R&D, Regulatory, and Executive teams) updated on trial metrics, data collection bottlenecks, and compliance health.

• Experience: 4–6+ years of clinical research experience within the medical device, medtech, or digital health space.
• Management: Prior experience managing or mentoring junior clinical staff (e.g., Clinical Coordinators or Assistants).
• Skills: Demonstrated success handling IRB submissions, maintaining TMFs, and tracking multisite trials or IITs.
• Knowledge: Deep familiarity with medical device documentation, internal V&V processes, GCP, and FDA regulations.
• Education: Bachelor's degree in a scientific, nursing, or healthcare-related field (CCRP or CCRA certification is a strong plus).

Innovation is what we do. Our values are how we make it happen. Butterflies are and believe in…

• Patient-Centric Innovators: Our mission is THE mission.
• Empowered to Impact: Every voice matters.
• One Team, One Goal: Unity fuels progress.
• Growth Champions: We embrace challenges.
• Action-Oriented Achievers: We follow through, every time.

Butterfly offers a hybrid work model for most positions, with team members spending two or more days a week in the office. While flexibility is key, we value in-person connections that spark creativity and teamwork. Our offices are designed for collaboration, with comfortable workspaces, stocked kitchens, and opportunities to connect with peers. This is a hybrid position that can be based in the Burlington, MA or New York City, NY office.

This role may require up to 50% travel.

• Comprehensive health insurance, encompassing dental and vision coverage, is provided to all our employees. As a health-tech company, we prioritize the well-being of our teams. We also contribute to Health Savings Account (HSA) accounts for all enrolled employees on an annual basis.
• Comprehensive Employee Assistance Program - we provide access to tools and resources to support your emotional health and day-to-day needs.
• 401k plan and match - we facilitate your retirement goals.
• Eligible employees will have the opportunity to participate in Employee Stock Purchase Plan (ESPP)
• Unlimited Paid Time Off + 10 Holiday Days a Year - recharge and come back ready to make an impact
• Parental Leave - we aim to provide our employees with time to bond with their growing family, along with additional support for primary caregivers to help transition back to work
• Competitive salaried compensation - we value our employees and show it
• Equity - we want every employee to be a stakeholder
• The opportunity to build a revolutionary healthcare product and save millions of lives!

Our estimated salary for this role in NYC is $200,000 + bonus + equity + benefits. Actual pay is determined by multiple factors such as skills, qualifications, experience and market demand.

Candidates must be authorized to work in the United States. Butterfly Network will not provide immigration sponsorship of any kind for this position, including but not limited to H-1B, TN, O-1, L-1, or green card sponsorship (this includes applicants who are in the process of obtaining a green card), now or in the future.

Butterfly Network does not accept agency resumes.

Butterfly Network is an E-Verify Company.

Butterfly Network is an equal opportunity employer. Regardless of race, traits associated with race, color, ancestry, religion, gender, national origin, sexual orientation, age, citizenship, marital status, disability or Veteran status. All your information will be kept confidential according to EEO guidelines.

Butterfly requires security adherence responsibilities from all employees. These include: adhering to all company security policies and procedures, utilize provided company assets securely, and complete all required security awareness training programs. Safeguarding company data and systems from unauthorized access, modification, or destruction, contributing to the overall security posture of the organization. Immediately reporting any suspected or actual security incidents, including phishing attempts, malware infections, or unauthorized access, following the established incident response procedure

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