Principal Process Development Engineer, Powder Scale-Up
Alsym Energy
Job Title Principal Process Development Engineer, Powder Scale-Up Job Summary Alsym Energy Inc. is seeking a hard-working, self-driven and highly technical Principal Process Development Engineer to lead the scale-up of active materials powders, and associated particle engineering processes, for next-generation energy storage systems. In this role, the candidate will serve as the senior technical authority for maturing powder production processes from lab- through to pilot-scale and toward volume manufacturing, working closely with a team of scientists and engineers to deliver products satisfying strict performance requirements. This is a hands‑on leadership role for someone who has built a career scaling inorganic electroactive-powders in an industrial setting and wants to shape the scale‑up strategy for a rapidly growing energy storage company. Industry Background Energy storage is one of the fastest-growing sectors in the global energy economy, with annual stationary storage capacity additions projected to grow 23% per year from 2025 to 2035, driven by surging electricity demand from electrification, data centers, and AI infrastructure. Alsym Energy is the leading developer of non-flammable, high-performance, low-cost sodium-ion batteries for AI data centers, utilities, commercial real estate and anywhere else energy storage is needed. Key Qualifications BS, MS, or PhD in Chemical Engineering, Materials Science and Engineering, Chemistry, or a related field. Minimum 15+ years of industry experience working with inorganic powders, with a demonstrated track record of scaling one or more powder synthesis processes from the precursor to the final product spanning research through to full- scale production. Proven ability to lead powder and particle scale‑up efforts end-to‑end, including equipment selection, process design, technology transfer, and pilot‑line or manufacturing start‑up. Deep, hands‑on expertise with synthesis techniques such as spray drying, co‑precipitation, or hydrothermal, including formulation and process optimization to meet particle size or morphological design and performance specifications. Significant hands‑on experience with powder processing methods including, calcination, sintering, carbonization, milling, and sieving. Strong fundamental understanding of colloid/surface chemistry, with experience optimizing dispersion and surface functionalization strategies. Experience establishing control plans and quality control/quality assurance programs, and leading root‑cause and FMEA-driven troubleshooting across process and manufacturing teams. Experience in batteries, catalysts, inorganic pigments, ceramics, or specialty materials is highly desired; experience in GMP or other regulated environments and technology transfer to CMOs or pilot facilities is a plus. Serve as the principal technical leader for particle engineering and cathode active materials powder scale‑up, developing and executing the strategy for optimizing and controlling properties such as particle size distribution, surface area, morphology, tap density and surface chemistry. Lead the design, optimization, and scale‑up of particle engineering processes such as spray drying, milling, calcination, sintering, and carbonization—from lab‑scale research through pilot‑line and into full-scale manufacturing. Serve as technical liaison between R&D, and external manufacturing partners, contributing to design of experiments, process documentation, and technology transfer. Partner with process development engineers and scientists to sustain and continuously improve existing and new particle engineering processes, including operations and material traceability across the line. Institute and own control plans and quality control/quality assurance programs to ensure consistent particle and electrode performance across batches and scales; collaborate across groups to diagnose and troubleshoot performance issues and conduct FMEA/RCA as required. Direct particle characterization efforts using techniques such as SEM, EDX, XRD, and particle size analyzers, and coordinate external testing as needed. Plan and coordinate experiments between synthesis and prototyping teams in order to establish key relationships between powder properties and electrode and cell level properties and performance characteristics. Evaluate the technical capabilities, equipment, and quality systems of prospective contract manufacturers and toll processors to assess fit for scale‑up. Mentor and provide technical guidance to junior and mid‑level engineers and scientists, and contribute to long‑term strategic planning for the powder engineering and scale‑up roadmap. Why Join Us? At Alsym, we believe in equitable compensation and a healthy work‑life balance. Beyond a competitive salary, we offer a benefits package designed to support you both inside and outside the office. Prime Location : We are within easy walking distance of the train station. Commuter Friendly : Enjoy the convenience of free on‑site parking. Health & Wellness : Stay active with access to our free on‑site gym. Friday Fuel : We provide free lunch delivery every Friday to celebrate the end of the work week together. Health & Dental: Premium insurance coverage through Blue Cross Blue Shield. Financial Future: Every employee is eligible for 401k plans and stock options. Time to Recharge : A flexible Paid Time Off (PTO) program to help you find your balance. Family & Security: Full eligibility for PFML (Paid Family and Medical Leave). Our Commitment to You We maintain a firm Anti-Harassment Policy that includes robust Diversity, Inclusion, Equity, and Gender Protections . We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Note: A full, detailed listing of all benefits will be provided following a formal offer of employment. #J-18808-Ljbffr Alsym Energy
$173k - $193k
Join the Alkermes Process Development team as a Principal Engineer, where you will lead late-stage drug product Process... ...molecule process development, scale-up and technical transfer to manufacturing... ...of processing techniques such as, powder blending granulation, compression,...PrincipalContract workLocal area- Amgen is seeking a Process Development Scientist to support drug product commercialization and scale-up in a fast-paced environment. You will design and execute characterization... ...commercial facilities. Collaboration with engineering, analytics, quality, and regulatory teams is...SuggestedRemote job
$141.84k - $191.9k
...them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Process Development Principal ScientistWhat you will doLet’s do this. Let’s change the world. In this vital role you will joining Amgen’s Attribute...PrincipalFull timeContract workImmediate startFlexible hours$140k - $154k
Join the Alkermes Process Development team as Senior Engineer, where you will provide technical leadership and support... ...of processing techniques such as, powder blending, encapsulation,... ...small molecule process development, scale up and technical transfer.Preferred...SuggestedLocal area$139.37k - $201.82k
...of What's Possible. Learn more at and on LinkedIn and X.The Principal Engineer - Process Reliability and Process Transfer is a senior technical leadership role responsible for driving innovation, development, and optimization of semiconductor manufacturing processes across...PrincipalPermanent employmentFull timeWork at officeDay shift- Job Title: Principal Power Electronics Applications Engineer - GaN / SiCLocation: Somerville, MA, - will provide relocation... ...evaluation, simulation/model development, and bench characterization of... ...trainings, demos). As the company scales, this position has the strong...PrincipalRelocation package
$148.5k - $214.5k
Job title: Senior Principal Scientist/Principal Scientist... ..., leveraging large-scale electronic health records... ...of drug discovery and development across Sanofi's... ...patients' lives. Join the engine of Sanofi’s mission —... ...for large-scale data processing Experience collaborating...PrincipalFull time- ...Small Molecule Process Development Engineer – Synthetic API Scale-Up & ModelingLocation: Cambridge, MA Employment Type: Contract Business Unit: DST Synthetics... ...molecule.Experience building and utilizing first principal models (reaction kinetics, mass transfer, separations...Permanent employmentContract work
- GC Therapeutics in Cambridge, MA is seeking a Scientist or Senior Scientist for the Process Development team. This role focuses on iPSC scale-up and differentiation from benchtop to production-scale bioreactors, contributing to cGMP processes for early-phase clinical trials...
- ...Senior Scientist to advance iPSC-based cell line development from bench to production scale. You will engineer iPSC-derived products for regenerative therapies and... ..., and R&D to drive product characterization and process improvements. #J-18808-Ljbffr GC Therapeutics
- Prime Medicine in Cambridge, MA is seeking a Senior Scientist / Senior Engineer to lead LNP process development, formulation, and scale‑up for our gene editing delivery programs. You will own bench‑to‑GLP/GMP process development, including formulation, process optimization...
- ...opportunities in therapeutic discovery, development, and manufacturing. We are building large-scale deep learning models of... ...Matterworks is seeking a Principal Software Engineer with full stack experience... ...Manage the entire development process from user problem to value delivery...PrincipalFull timeTemporary workFlexible hours
$188k - $257.5k
...Principal Software Engineer - Agentic Platform Cambridge, MA USA The Role The Pioneering Intelligence... ...and operated distributed systems at scale and wants to take agency AI from... ...10+ years of professional software development experience. Demonstrated track record...Principal$188k - $259k
...seeking a Director, Oral Drug Product Development to provide scientific and... ...This role leads scientific and engineering efforts supporting formulation and process development across early- and late... ..., manufacturability assessment, scale-up, technology transfer, and clinical...PrincipalFull timeTemporary workLocal area- ...Senior Or Principal Data Scientist/Machine Learning ScientistWe... ...of building and scaling data science products... ...making and model development.Develop and deploy machine... ...with software engineers.Identify success metrics... ...advancements to improve existing processes and develop new...PrincipalWork at office
- United Therapeutics Corporation in Cambridge, MA seeks a Senior Scientist, Process Development to design, optimize, and scale iPSC expansion and differentiation for clinical and commercial manufacturing. You will lead development strategies, collaborate across teams for...
$95k - $245k
...nonprofit research and development company headquartered... ...exploration to biomedical engineering, lives often depend on... ...:We are seeking a Principal Electrical Engineer to... ...integrated into large-scale systems. The engineer... ...location during the hiring process. Please note that the...PrincipalFull timeWork at officeLocal areaFlexible hours$140.8k - $211.2k
...a member of the Drug Substance Control Strategy team in Analytical Development, this role will support synthetic drug development programs at Vertex with a focus on small molecule drug substance process and control strategy development across clinical and commercial-enabling...PrincipalFull timeContract workSummer workFlexible hours$220k - $269.5k
...Operating Principal – Summit PBU THE ROLESummit, a Pioneering Business... ...Principal to help launch and scale our NewCos. You will work... ...strategy, driving corporate development, and partnering closely with... ...obligations. Your application data is processed through Greenhouse, our...Principal$95k - $245k
...nonprofit research and development company headquartered... ...to biomedical engineering, lives often depend on... ...innovative and driven Principal Optical Engineer (PMTS... ...sensors and corresponding processing algorithms. In this... ..., and execute large scale technical software and...PrincipalFull timeLocal area$170k - $235k
Principal Software Engineer, AI EngineeringCambridge, MA About this position:Context... ...leader within the development team, the engineer will lead... ...topics relating to building, scaling, and performance of AI... ...application or interview process, perform essential job functions...Principal- UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...Principal
- Harvard Kennedy School in Cambridge, MA seeks an experienced Director, Principal & Major Gifts to manage a 75-100 prospect portfolio and lead fundraising strategies for School priorities. You will work closely with faculty, senior administration and University officials...Principal
- ...-enabled drug discovery and development. Create scalable, interoperable... ..., knowledge architects, AI engineers, and platform teams to... ...sciences informatics; enterprise-scale product delivery. Experience... .../lakehouses; distributed processing; APIs/data services; data cataloging...PrincipalImmediate start
- Google Inc. is seeking a seasoned Network Engineer to own outcomes and drive decisions across a complex global network. You will influence... ..., and apply deep domain expertise to maintain reliability at scale. Responsibilities include monitoring performance, coordinating...
- ...Principal Software Developer/ArchitectWakefieldExp 7-10 yearsDeg BachelorsReloBonusJob... ...be part of the core product development team, working on our next... ...in designing large scale enterprise web applications.•... ..., UML and Rational Unified Process.• Experience in modularity,...Principal
$199.8k - $270.3k
...pioneering RNAi therapeutics and scaling rapidly across research, development, and global commercialization. The... ...infrastructure.Lead enterprise detection engineering, delivering advanced analytics and... ...to an inclusive recruitment process and equal employment opportunity....PrincipalFull timeTemporary workLocal areaFlexible hours$188k - $257.5k
...problems. We are seeking a Principal Software Engineer to own the underlying... ...operated distributed systems at scale and wants to take agentic... ...of professional software development experience. Demonstrated track... ...Your application data is processed through Greenhouse, our...Principal- ...Ventures, is pioneering the development of precision-targeted... ...sets at unprecedented scale and resolution, we are... ...of protein design and engineering, synthetic biology,... ...an experienced Principal Scientist to help establish... ...expression, purification, and process development....PrincipalFull timeLocal area
$142.5k - $256.5k
...are evaluated and refined at scale. In addition to antigen-focused... ..., Biochemistry, Protein Engineering, or a related field.5+ years... ...ownership consistent with a Principal Scientist role.Here’s What You... ...in connection with the hiring process and/or to perform the essential...PrincipalPermanent employmentFull timeWork at officeWork from home
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Process Development Engineer, Powder Scale-Up. Be the first to apply!
- education development Malden, MA
- community development Malden, MA
- career development Malden, MA
- professional development program Malden, MA
- training development Malden, MA
- training and development intern Malden, MA
- housing development Malden, MA
- staff development nurse Malden, MA
- entry level child development Malden, MA
- engineering director




