Sr. Technical Program Manager, AI Security
$145.9k - $234.2kModerna Therapeutics
The Role:Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. We’re looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.Here’s What You’ll DoProgram Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process Build processes, templates, and structure, or leverage existing ones as appropriate Manage vendors, schedule, scope, and cost Measure program success (or lack thereof) and risks using data and facts Provide balanced risk remediation strategies and recommendations and drive risk mitigation Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna Provide clear, accurate, consistent, and timely communications Advance good infrastructure and security practices and culture Partner Collaboration - work with Cybersecurity, Builder Tools & Platforms, Infrastructure, Identity & Endpoint Engineering, GRC, AI Engineering, Data, Enablement/L&D, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner Manage multiple initiatives to oversee the architecture and lifecycle of enterprise AI systems, including agent identity, tool authorization, and secure development practices; to drive governance frameworks that define permitted AI use, contextual standards, and regulatory alignment — including GxP where applicable; and to ensure end-to-end observability and monitoring of AI agents in production. Own the operating model for AI enablement programs, including pilots, cohorts, and phased rollouts, and partner with Enablement/L&D teams to shape role‑based learning paths for AI builders Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes Here’s What You’ll Need (Basic Qualifications)8+ years of Technical Program Management or Engineering Program Management in Artificial Intelligence (AI) / Machine Learning (ML) heavy environments is requiredHere’s What You’ll Bring to the Table (Preferred Qualifications)Background in software engineering, data science, or machine learning Experience with LLM platforms, prompt engineering workflows, or AI copilots Experience with AI development platforms, copilots, developer tooling, or MLOps concepts Experience with responsible AI, model governance, or compliance frameworks Experience driving structured, process-driven AI transformation initiatives. Familiarity with tools such as Kubernetes, Airflow, MLFlow, or similar MLOps stacks Familiarity with governed enablement models (e.g., citizen development, platform standards, golden paths) Knowledge of security and compliance standards relevant to AI and AI-assisted engineering. Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders Embrace a culture of continuous service improvement and service excellence A desire to make an impact as part of a high-growth, transformational company Experience with GxP environments and regulatory requirements Technical Depth: Strong understanding of AI/ML systems, including model training pipelines, LLMs, MLOps, data pipelines, and cloud infrastructure Strong understanding of AI/ML development workflows, AI‑assisted engineering tools, or modern software development platforms Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion Experience improving developer productivity and building internal tools/platforms. Ability to define metrics, analyze tradeoffs, and drive decisions with data. Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback Proven ability to operate in highly matrixed environments and influence without direct authority. Excellent written and verbal communication skills, including executive‑level storytelling Pay & BenefitsAt Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.Competitive healthcare, plus voluntary benefit programs to support your unique needsA holistic approach to well-being, with access to fitness, mindfulness, and mental health supportFamily planning benefits, including fertility, adoption, and surrogacy supportGenerous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdownSavings and investments to help you plan for the futureLocation-specific perks and extrasThe salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Our Working Model As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment. Equal OpportunitiesModerna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. AccommodationsWe’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at View email address on click.appcast.io. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license. #LI-CK1-SummaryLocation: Cambridge, Massachusetts; Seattle, Washington; DigitalType: Full time
$157k - $210k
...is The Essential Cloud for AI™. Built for pioneers by pioneers... ...performance with deep technical expertise to accelerate breakthroughs... ...processes, and tools. As a security technical program leader focused on... ...security and Identity & Access Management (IAM), you will work across...SeniorPermanent employmentFull timeTemporary workCasual workWork at officeFlexible hours- ...in Richland/Seattle is seeking a Senior Technical Project Manager to lead software implementation... ...operation. The role requires national security domain knowledge, software engineering or data science expertise, applied AI, and strong agile management to align scope...Senior
$148.7k - $201.2k
...is to make agent driven infrastructure management fast , reliable and safe. The Provider... ...resources. We are investing heavily in AI assisted platform capabilities that will... ...expand coverage. We are seeking a Senior Technical Program Manager (TPM) to lead testing and...SeniorFlexible hours$171k - $231.4k
...ready to be at the forefront of Agentic AI innovation and redefine the future of communication? Join our team as a Sr TPM and lead futuristic initiatives that... ...of what's possible with Alexa+.As a Sr. Technical Program Manager, you'll drive the development of next-generation...SeniorLocal areaFlexible hours$148.7k - $201.2k
...and Browse Node Classification team is seeking an experienced Technical Program Manager to drive solutions for classifying all products into the... ...help build systems that are partially or entirely powered by AI and ML. The systems are responsible for handling continuous...SeniorFlexible hours$148.7k - $201.2k
...an opportunity tailored for you.We are looking for a Senior Technical Program Manager for our team in Seattle, WA. You'll help build the testing and... ...including in Critical Program Reviews- Help the team adopt AI-assisted workflows in its own tooling and processesA day in...SeniorLive inFlexible hoursNight shift$148.7k - $201.2k
As part of the AWS Applied AI Solutions organization, our vision... ...of companies worldwide to manage day-to-day operations. We will... ....We are looking for a senior Technical Program Manager to join the... ...people, teams, and AI collaborate securely from anywhere to create unprecedented...SeniorContract workRemote workWorldwideFlexible hoursNight shiftDay shift$148.7k - $201.2k
...Understanding and Enrichment) organization is seeking a Senior Technical Program Manager to lead complex, cross-organizational programs that drive... ...complex problem spaces, and deliver solutions that leverage ML/AI capabilities to advance our mission of being the first-stop...SeniorTemporary workWorldwideFlexible hours$171k - $231.4k
...help customers control and secure access to some of the most sensitive... ...are looking for a motivated Technical Program Manager with the desire and talent... ...to our vision. As a Sr. Technical Program Manager on... ...onboarding tools, leveraging AI to reduce manual coordination...SeniorLocal areaFlexible hours$148.7k - $201.2k
...part of the AWS Applied AI Solutions organization,... ...companies worldwide to manage day-to-day operations.... ...want to join an ambitious program that continues to push... ...to work with multiple technical teams at Amazon in... ...Compliance, EMC, Firmware, Security and Networking.- Proven...SeniorWorldwideOverseasFlexible hours$194k - $278.3k
...the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized... ...and careers to the next level.We are hiring a Staff Technical Program Manager for our Security organization. Security at Snowflake spans Product Security...$163.6k - $221.3k
...through advanced generative AI technologies -... ...possible in these fields.As a Sr TPM you will... ...will be responsible for managing multiple projects, while... ..., and possess a strong technical background focused on problem... ...of technical product or program management experience-...SeniorFlexible hours$148.7k - $201.2k
...Science (MADS) Reporting Engines team is looking for a Senior Technical Program Manager to own end-to-end delivery of complex engineering programs... ...program-manage the evolution of measurement systems toward AI-powered, natural-language-driven insights while maintaining...SeniorFlexible hoursDay shift$180.2k - $243.34k
...and operating the world's best data and AI infrastructure platform, enabling our... ...seeking an exceptional Senior Staff Technical Program Manager (TPM) for Reliability to lead the strategy... ..., Compute Fleet Management, SRE, Security, and Cloud Partnerships.Drive Execution...SeniorLocal areaWorldwide- ...things they had to do. Powerful AI will be the biggest lever... ...to the world. The Security Team Examples of key problems... ...Build the entire security program from scratch. Most leaders... ...where you would. You've run technical program management for a security or...
$157k - $210k
CoreWeave is The Essential Cloud for AI™. Built for pioneers by pioneers, CoreWeave... ...superior infrastructure performance with deep technical expertise to accelerate breakthroughs... ...more at About The Role As a Technical Program Manager focused on Networking Capacity Delivery,...SeniorPermanent employmentFull timeTemporary workCasual workWork at officeFlexible hours$148.7k - $201.2k
We are hiring a Senior Technical Program Manager within the Associate Experience (AE) organization to drive the delivery and execution of CSALT (Customer... ...the full range of customer interaction experiences — from AI-driven automated resolutions to human-assisted support...SeniorFlexible hours$171k - $231.4k
...engineers, supply chain specialists, security experts, operations managers, and other vital roles. You'll... ...Nvidia's latest GPU offerings to power AI/ML workloads across AWS's compute... ...Infrastructure Services is seeking a Senior Technical Program Manager to drive end-to-end...SeniorLocal areaWorldwideFlexible hours$236k - $339.2k
...agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are... ...technology and careers to the next level.We are hiring a Manager, Technical Program Management for our Security organization. Security at Snowflake spans Product Security...SeniorShift work$136k - $170k
...freedom to access, move, and manage their money wherever... ...globally, providing secure, simple, and reliable ways... ..., you'll bring AI further into how we build... ...engineering to build out the technical maturity behind that... ...processes that scale a program, including defining metrics...SeniorFull timeWork at officeWorldwideFlexible hours3 days per week$148.7k - $201.2k
Agentic AI drives innovation at the forefront of artificial intelligence... ...you.Key job responsibilities• Manage Strategic Initiatives : Lead cross-functional technical initiatives from start to finish... ...OP1/OP2 planning). • Technical Program Leadership: Monitor large-scale...SeniorWorldwideFlexible hours$166k - $238.05k
...in this new era, we seek AI-native thinkers across every... ...scalable and elastic data management. Armed with great technical talent, our expanding... ...experienced Senior Technical Program Manager who can be part of... ...company’s confidentiality and security standards for handling...SeniorFlexible hours$163.6k - $221.3k
...baby registry in the U.S. serving millions of customers, and Marketing AI transforming how thousands of marketers work through AI-native workflows. We are looking for a Senior Technical Program Manager who can operate across both, driving execution on complex cross-...SeniorWorldwideFlexible hours- ...systems is powered by Lattice OS, an AI-powered operating system that turns thousands... ...JOBWe are seeking a highly motivated Technical Program Manager (TPM) to oversee the software release... ...Talent acquisition process and the security of our candidates. We've observed a...SeniorFull timeWork experience placementImmediate start
$148.7k - $201.2k
...team configures, deploys, and manages Microsoft 365 productivity services, delivering secure, reliable, and highly-available... ...self-motivated, highly organized Technical Program Manager (TPM) with exceptional... ...mobile security, cloud security, AI security, identity and access...SeniorFlexible hours$148.7k - $201.2k
The Amazon Games GenAI team is seeking a hands-on Senior Technical Program Manager to help us deliver innovative Gen AI games that unlock new types of gameplay. In this role, you will work across a portfolio of AI games at different phases of the production lifecycle,...SeniorCasual workLocal areaFlexible hours$148.7k - $201.2k
...right candidate, you will possess a strong program management background, have demonstrated... ...large projects, and have a well-rounded technical background. You must be able to thrive... ...including state-of-the-art Generative AI — and industry-standard products, pairing...SeniorFlexible hours$148.7k - $201.2k
...sales success for Amazon Connect customers through strategic engagement on migrations, expansions, and AI adoption initiatives. This Senior Technical Program Manager role owns the end-to-end reporting, tooling, and operational program management function for the Connect...SeniorFlexible hours$146.4k - $206.78k
...intelligent agreement management, Docusign unleashes business... ...Senior TPM in Product Security, you will shape and... ...by building scalable programs, driving adoption of... ...role reporting to the Sr. Manager, Security Product... ...principlesTranslate technical risk into business...SeniorPermanent employmentFull timeContract workWork at officeLocal areaRemote workShift work2 days per week$166k - $258k
....Nordstrom Technology is moving to an AI Native operating model, and we're rebuilding... ...speed increases. We need a Senior 2 Technical Program Manager to bring order and rigor to this... ...builds consensus across engineering, security, and architecture teams, and navigates...SeniorFull time
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Sr. Technical Program Manager, AI Security. Be the first to apply!
- technical manager Seattle, WA
- technical product manager Seattle, WA
- technical program manager Seattle, WA
- technical marketing manager Seattle, WA
- technical director Seattle, WA
- senior technical director Seattle, WA
- senior technical manager Seattle, WA
- senior technical product manager Seattle, WA
- technical services manager Seattle, WA
- technical director engineering Seattle, WA


