Data Scientist II, Outcomes Research

Responsibilities Lead and execute HEOR and real-world evidence (RWE) projects (e.g., outcomes analysis, treatment patterns, health‑care resource utilization) with external Pharma, academic, and other partners. Represent the Outcomes Research function and collaborate with internal and external stakeholders in the design, analysis, interpretation and publication of real‑world studies. Work on complex problems, exercising judgment in selecting and adapting appropriate epidemiologic and health‑economic methodologies. Partner with interdisciplinary groups of scientists, engineers, and product developers to translate research into clinically actionable insights for our clients. Stay current with the latest methodological advances in RWE, including causal inference and pharmacoepidemiologic methods. Build analytical infrastructure, including reusable code, templates and workflows that improve speed and quality across engagements. Comply with all applicable regulations, Tempus data governance and company procedures related to real‑world data use and reporting. Required Experience Advanced degree (Master’s with 2+ years of experience or equivalent) in data science, bioinformatics, biostatistics, epidemiology, immunology, public health or related quantitative field. Demonstrated computational skills using R and SQL, specifically applied to large‑scale healthcare datasets. Preferred Qualifications Strong data manipulation and analytical skills tailored to observational/real‑world data. Deep familiarity with HEOR and RWE methodologies, including approaches to address confounding (e.g., propensity score matching, weighting, inverse probability of treatment weighting). Experience analyzing large, complex real‑world datasets including administrative claims, electronic health records (EHR) and/or clinico‑genomic databases. Strong communication and presentation skills with the ability to translate complex methodologies and findings for non‑technical stakeholders. Self‑driven mindset with demonstrated ability to tackle ambiguous problems and work effectively in interdisciplinary teams. Experience with time‑to‑event analysis and survival methodologies. Experience working in oncology and/or analyzing outcomes related to cancer genetics, immunology, or molecular biology. Collaborative working style, eagerness to learn and high‑integrity work ethic with sharp attention to detail. Strong evidence‑based inference and explicit assessment and communication of study limitations. Nice to have: experience with version control (e.g., Git), software testing or validation processes, Phase II‑IV clinical trials, regulatory submissions to FDA or other health authorities, model building and validation, feature engineering, performance assessment, client‑facing or consulting experience, and comfort presenting results and recommendations to external stakeholders. Salary and Benefits Base salary range: ‘Chi’: $90,000–$135,000; ‘NYC/SF’: $100,000–$150,000. Salary may vary by location (Colorado, Illinois, New York) and qualifications. Benefits may include incentive compensation, restricted stock units, medical and other benefits. Remote roles may be available for individuals in unincorporated Los Angeles and other locations. EEO Statement We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status or disability status. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance and the California Fair Chance Act. Tempus reasonably believes that criminal history may have a direct, adverse relationship with the following job duties: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets and protected health information; and appropriately handling such information in accordance with legal and ethical standards. A conditional offer of employment may be withdrawn if a criminal history is found to adversely affect performance of these duties. #J-18808-Ljbffr