Sr. Accounting Manager - Clinical

Senior Accounting Manager – Clinical (Biotech/Pharma)

San Francisco, CA (Hybrid)

A growing, mission-driven biopharma company is seeking a Senior Accounting Manager – Clinical to join its expanding accounting team. This role is highly visible and plays a critical part in the R&D accounting close process, with a primary focus on clinical trial accounting.

This organization is dedicated to advancing innovative therapies for patients with serious and often underserved conditions, offering the opportunity to make a meaningful impact while working in a fast-paced, collaborative environment.

What You’ll Do

• Lead month-end and quarter-end close activities related to clinical R&D accruals
• Own and maintain the clinical cost tracker (expenses, prepayments, deposits, accruals)
• Prepare journal entries, reconciliations, and supporting schedules in accordance with US GAAP and SOX requirements
• Partner cross-functionally with Clinical Operations, FP&A, and external vendors to ensure accurate and timely reporting
• Review clinical budgets and incorporate estimates into financial reporting
• Analyze vendor contracts, purchase orders, and work orders to determine appropriate accounting treatment
• Perform variance and fluctuation analysis across clinical programs, entities, and development phases
• Support audits and ensure compliance with internal controls
• Contribute to system implementations and process improvement initiatives related to clinical cost tracking and reporting
• Assist with ad hoc projects and special initiatives

What We’re Looking For

• Bachelor’s degree in Accounting or Finance (CPA or CMA preferred)
• 6+ years of progressive accounting experience, ideally within biotech or pharma
• Strong understanding of clinical trial accounting and R&D processes
• Experience with public company environments and SOX compliance
• Background combining public accounting (Big 4 preferred) and industry experience is highly valued
• Proficiency with ERP systems (SAP, Oracle, NetSuite or similar) and strong Excel skills (pivot tables, lookups, advanced formulas)
• Ability to analyze complex vendor contracts and apply accounting judgment under US GAAP
• Strong attention to detail with the ability to manage competing priorities in a fast-paced environment
• Excellent communication skills and experience collaborating cross-functionally

Why Join

• Purpose-driven organization focused on improving patient outcomes
• Highly collaborative and innovative culture
• Competitive compensation package including bonus and equity
• Comprehensive benefits
• Flexible PTO
• Strong emphasis on professional development and growth
• Opportunity to work alongside cross-functional teams across multiple locations

Equal Opportunity Employer/Veterans/Disabled

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The Company will consider qualified applicants with arrest and conviction records in accordance with federal, state, and local laws and/or security clearance requirements, including, as applicable:

• The California Fair Chance Act

• Los Angeles City Fair Chance Ordinance

• Los Angeles County Fair Chance Ordinance for Employers

• San Francisco Fair Chance Ordinance