Senior Manager, CRM & Lifecycle Marketing

< Overview

The Senior Manager, CRM & Lifecycle Marketing is responsible for executing and optimizing lifecycle marketing programs across owned channels (email, SMS, direct mail), with a focus on building and delivering scalable, data-driven customer engagement.

This role is a core operator within the Global Omnichannel model, partnering with business unit marketing teams and Omnichannel leads to translate defined journey strategies into activated, compliant, and measurable campaigns within enterprise CRM platforms.

This is a hands-on campaign execution role with high visibility, focused on building and deploying lifecycle programs within IT-managed platforms, operating within defined strategy, platform architecture, and data models.

Key Responsibilities

Lifecycle Program Execution & Optimization

• Execute and optimize multi-channel lifecycle programs aligned to defined brand strategies and omnichannel priorities
• Translate approved journey designs into activated campaigns, ensuring sequencing, timing, and audience alignment
• Support the scaling of lifecycle programs across acquisition, onboarding, engagement, retention, and reactivation
• Partner with U.S. and International teams to execute lifecycle programs that are globally consistent and locally adaptable within regulatory requirements
• Continuously optimize lifecycle programs based on performance insights, business priorities, and customer behavior

CRM Campaign Activation (Within IT-Managed Frameworks)

• Execute lifecycle campaigns within Salesforce Marketing Cloud (SFMC), including audience creation, journey configuration, QA, and deployment, leveraging IT-defined data models and platform frameworks
• Apply approved segmentation and personalization logic using available first- and third-party data sources
• Build and manage campaign setup, scheduling, and execution in a timely, detail-oriented manner; troubleshoot campaign issues, driving continuous improvement in CRM capabilities
• This role operates within established platform configurations and does not own system administration, data engineering, or platform infrastructure.

Cross-Functional Platform & Data Partnership

• Partner closely with Omnichannel Operations Leads to execute against defined journey strategies and campaign sequencing
• Collaborate with Advanced Analytics and Data Strategy to apply segmentation, targeting, and personalization approaches
• Partner with IT and Data teams to ensure campaign readiness, data availability, and platform reliability
• Serve as a key liaison with external agencies and vendors supporting CRM execution

Campaign Operations, QA & Optimization

• Troubleshoot campaign-level issues (e.g., audience logic, journey behavior, delivery performance) and partner with IT on system-level root cause resolution
• Execute test-and-learn plans, including A/B and multivariate testing
• Optimize channel performance, including cadence, frequency, and engagement

Governance, Compliance & Scalable Execution

• Execute campaigns in alignment with compliance, consent, and regulatory requirements (e.g., HIPAA, GDPR, OneTrust frameworks)
• Maintain campaign documentation, QA processes, and audit readiness
• Leverage and contribute to standardized templates, modular assets, and reusable lifecycle frameworks
• Ensure campaigns align with omnichannel plans and cross-channel coordination

Performance, Measurement & Enablement

• Track and report on lifecycle performance metrics (engagement, conversion, retention, deliverability)
• Partner with Advanced Analytics & Data Strategy to connect campaign performance to business outcomes
• Provide insights and recommendations to improve lifecycle execution and effectiveness

Expected Outcomes (First 6-12 Months)

• Execute foundational lifecycle journeys (onboarding, engagement, reactivation) across priority brands
• Establish consistent, high-quality campaign execution processes within SFMC aligned to IT governance
• Implement structured testing and optimization roadmap
• Enable standardized lifecycle templates and workflows across teams
• Demonstrate measurable improvements in engagement, conversion, and retention

Qualifications

Required

• 5+ years in CRM, lifecycle marketing, or digital marketing in a complex or regulated environment
• Hands-on experience executing campaigns in Salesforce Marketing Cloud or similar platforms
• Experience translating journey strategies into activated campaigns
• Strong understanding of customer lifecycle and multi-channel orchestration
• Experience working cross-functionally with marketing, analytics, and technology teams

Preferred

• Experience in biopharma, healthcare, or regulated industries
• Familiarity with Salesforce Data Cloud, Marketing Cloud Personalization
• Working knowledge of SQL, AMPscript, or similar tools (for campaign execution, not engineering)
• Experience supporting global lifecycle programs
• Exposure to consent, preference management, and privacy frameworks

#LI-SS1 #LI-Hybrid

U.S. Pay Range

$142,800.00 - $193,200.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website:

AboutAlnylam

We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

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