Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Member of Technical Staff - Infrastructure

$150k - $300k

Phylo

About Phylo Phylo is an applied research lab building agentic intelligence to accelerate discovery for every biomedical scientist. We believe AI agents will fundamentally transform how biomedical research is done, enabling faster and more systematic scientific progress. Our growing team brings together world-class researchers and engineers across AI and biology. Backed by a $13.5M seed round led by a16z, Menlo Ventures, and Anthropic, and advised by Nobel Prize laureate and pioneering biologists, Phylo is building the next generation of AI systems for the life sciences. About The Role We’re looking for an Infrastructure Engineer to build, operate, and scale the deployment foundations for Phylo’s enterprise AI platform. This role is focused on the systems that let Phylo run reliably in real‑world customer environments: cloud infrastructure, Kubernetes, secure single‑tenant deployments, observability, networking, storage, and operational workflows. You’ll help bring Phylo’s agentic AI platform into enterprise pharma, biotech, and research environments where security, reliability, data isolation, and deployment discipline matter deeply. You’ll work closely with engineering, ML, science, and customer‑facing teams to make Phylo easy to deploy, monitor, support, and scale across cloud and customer‑managed environments. What You’ll Work On Design, build, and operate infrastructure for Phylo’s enterprise deployments, including single‑tenant and customer‑hosted environments. Build deployment systems for cloud‑native and enterprise environments, own Kubernetes‑based infrastructure for Phylo services, sandboxed agent execution, compute workloads, storage mounts, networking, and observability. Support infrastructure for scientific and computational workloads, including HPC‑adjacent workflows, bioinformatics tools, batch execution, GPU/CPU compute, and large‑scale file/data movement. Work with customer‑facing teams to support enterprise deployment planning, debugging, reliability reviews, and production operations. Help define the long‑term architecture for deploying Phylo into pharma, biotech, academic, and research environments. Requirements 2+ years of industry experience in infrastructure engineering, DevOps, SRE, platform engineering, cloud engineering, or a similar role. Strong hands‑on experience with Kubernetes in production. Experience deploying and operating systems on AWS, GCP or Azure. Experience with infrastructure‑as‑code tools such as Terraform, Pulumi, CDK, or similar. Strong understanding of networking, IAM, VPCs, load balancers, DNS, certificates, secrets management, and cloud security fundamentals. Experience building CI/CD pipelines, deployment automation, environment provisioning, and operational tooling. Nice to Haves Experience deploying enterprise SaaS into single‑tenant, customer‑hosted, VPC‑isolated, or regulated environments. Experience building or maintaining R&D infrastructure in pharma, biotech, academic research, or life sciences organizations. Experience with HPC, bioinformatics infrastructure, scientific computing, workflow engines, or batch schedulers. Experience with tools or systems such as Nextflow, Snakemake, Cromwell, Slurm, AWS Batch, EKS, ECS, FSx, Lustre, S3, or distributed filesystems. Experience with secure sandboxing or isolated execution environments such as gVisor, Kata Containers, Firecracker, or Kubernetes sandboxing. Experience supporting GPU‑enabled workloads, large‑scale data processing, or scientific compute clusters. Experience with enterprise identity, SSO, audit logging, compliance controls, customer networking, VPNs, private connectivity, or data residency requirements. Experience working directly with enterprise customers during deployment, onboarding, debugging, or production support. Why Join Us? Competitive salary and equity share in building the future of biomedical discovery Full medical, dental, and vision coverage, including free therapy sessions and eyewear stipend 401(k) to help you build long‑term financial security (US only) Unlimited PTO to recharge when you need it (US only) Lunch and snacks when you’re in the office Regular team offsites and company events A culture of excellence and speed - we move fast, think big, and support each other every step of the way Your work will directly impact our mission to 100X biomedical discoveries through AI Compensation Range: CA$150K - CA$300K #J-18808-Ljbffr

Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Member of Technical Staff - Infrastructure in South San Francisco, CA vacancy
  • $250k

     ...compute platform building the next generation of agentic infrastructure for GPU-intensive workloads. Operating across the full technology...  .... This opportunity offers the chance to join as a Member of Technical Staff at a pivotal stage in the company's growth. You'll help... 
    Suggested
    Full time
    San Francisco, CA
    7 days ago
  • About Us Gimlet is building the next generation of AI infrastructure: large-scale AI datacenters and the orchestration platform that coordinates them. The future of AI will require vastly more compute than exists today. But as AI workloads become more complex and new... 
    Suggested

    Gimlet Labs

    San Francisco, CA
    5 days ago
  • $150k - $250k

     ...people take ownership, grow together, and share both the challenges and the wins. What you'll do Build the supercomputing infrastructure that runs our agents. Our agents tackle long-horizon, high-performance workloads, and you'll design the cloud compute,... 
    Suggested
    Work at office
    Remote work
    Flexible hours

    Asari AI

    San Francisco, CA
    more than 2 months ago
  • $250k - $300k

     ...next step in your career? Join one of the most interesting infrastructure companies in the AI space right now. Founded by two of the most...  ...Skills / Must Have: A track record of impressive technical work you can speak to in depth; the years matter less than the... 
    Suggested
    Full time
    Remote work
    San Francisco, CA
    7 days ago
  • $250k - $300k

     ...champions growth and development? Join one of the most exciting AI infrastructure companies in the market, building a platform that deploys and...  ...Skills / Must Have: ~ A track record of impressive technical work you can speak to in depth, the years matter less than the... 
    Suggested
    Full time
    Remote work
    San Francisco, CA
    7 days ago
  •  ...requirements, and very few precedents to copy from. About the Role Members of Technical Staff (MTS) are the senior engineers who build the platform...  ...is systems engineering at its core. Multi‑tenant data infrastructure across very different portcos. Event‑driven pipelines... 

    BEACON SOFTWARE COMPANY

    San Francisco, CA
    5 days ago
  • $200k

     ...frontier startups and F500 enterprises. THE ROLE As the Member of the Technical Staff, you are the “PM of the model,” architecting the next generation...  ...that are critical to scaling data for AGI/ASI. System Infrastructure : Collaborate closely with engineering teams on data... 
    Flexible hours

    Abundant Energy Inc.

    San Francisco, CA
    4 days ago
  •  ...building the most capable models on earth as a thought partner. Backed by Y Combinator. About the Role As a Member of Technical Staff, you will build the core infrastructure and environments that train AI models to do real work. You'll operate across the full stack, from... 

    Traverse PC Inc

    San Francisco, CA
    4 days ago
  •  ...Pixeltable Inc. Member of Technical Staff San Francisco, CA·Full time Apply for Member of Technical Staff As a founding member of the engineering...  ...lies in empowering teams to focus on innovation, not on infrastructure. We aim to simplify the AI development stack, allowing... 
    Full time
    Part time
    Work at office
    Work from home
    Flexible hours
    2 days per week

    Pixeltable, Inc.

    San Francisco, CA
    1 day ago
  • $200k - $400k

     ...engineering, tackling foundational technical problems that most teams don't even...  ...database and memory systems, real-time LLM infrastructure, human-AI operating system design,...  ...what AI can do. We're looking for a Member of Technical Staff who is obsessed with hard, novel,... 
    Full time
    Remote work
    Visa sponsorship
    Flexible hours

    CLERA

    San Francisco, CA
    3 days ago
  •  ...structures that shaped the open web and modern computing infrastructure, the Foundation serves as a neutral, multi-stakeholder convening...  ...The Role The OpenClaw Foundation is seeking exceptional Members of Technical Staff (MTS) to serve as full-time maintainers, builders, and... 
    Full time

    OpenClaw Foundation

    San Francisco, CA
    4 days ago
  •  ...longer whether quantum and AI converge; it is who builds the infrastructure to make that convergence reliable, scalable, and useful....  ...ours at the frontier of science. Role Overview As a Member of Technical Staff you will shape Conductor's core offerings: AI software that... 

    Conductor Quantum

    San Francisco, CA
    3 days ago
  •  ...uses Shapes every single day, and everyone talks to users. Member of Technical Staff is the title we use for engineers who own hard problems...  ...scale High-performance Python backends at scale Realtime infrastructure (WebRTC, WebSockets, streaming) for chat, voice, or video... 

    Shapes, Inc

    San Francisco, CA
    4 days ago
  •  ...the next Transformer or next AlphaFold breakthrough. As a Member of Technical Staff, you will build this autonomous AI research system to...  ...evolutionary search algorithms, agent loops, parallel GPU infrastructure, and fine-tuning. What You’ll Work On Autonomous AI R&D... 

    Thesis (YC F25)

    San Francisco, CA
    3 days ago
  • $200k

    Join to apply for the Member of Technical Staff role at Listen Labs . TL;DR: We are seeing strong market demand and an aggressive 6‑month product...  ...product and must make decisions across the LLM pipeline, infrastructure, backend, and UX. You have a high bar for quality: In a... 
    Flexible hours

    Listen Labs

    San Francisco, CA
    1 day ago
  • Catalog is building the commerce layer for AI - the missing infrastructure that lets agents not just search the web, but understand,...  ...reshape how people discover and buy online. Role As a Member of Technical Staff, you will ship core systems, set engineering culture, and... 
    Work at office

    Getcatalog

    San Francisco, CA
    2 days ago
  •  ...environments for Fortune 500 companies. About the Role As a Member of Technical Staff, you will be part of the team responsible for the work...  ...entire stack. The MTS works vigorously on the underlying infrastructure, core features, agent configurations, and user experience... 
    Work experience placement
    H1b
    Work at office
    Visa sponsorship

    Product Pulse

    San Francisco, CA
    5 days ago
  • $227.5k - $401k

     ...motivated individuals who tackle unique technical challenges at scale and solve them...  ...financial technology sector. As a Member of Technical Staff, you will operate with a high degree...  ...Experience in AI‑enabled fintech or infrastructure companies. Familiarity with classical... 
    Work at office
    Immediate start
    Relocation
    Flexible hours

    Adyen

    San Francisco, CA
    5 days ago
  • As a Member of Technical Staff (MTS), you'll build production-grade systems that power continuous optimization loops for AI agents—from evaluation pipelines and data/trace infrastructure to APIs that deploy improved policies. This role is a blend of MLE + backend engineering... 

    VizopsAI

    San Francisco, CA
    1 day ago
  • About the job Member of Technical Staff - Full Stack / AI Systems Company: AdsGency AI Location: Onsite (San Francisco City) Employment Type...  ...’ll be one of the core builders of AdsGency’s AI-driven infrastructure — designing, architecting, and scaling systems that... 
    Full time
    Work experience placement
    Visa sponsorship

    Mosaic.tech

    San Francisco, CA
    4 days ago
  • $200k - $300k

     ...fast-growing AI inference company in San Francisco to hire Members of Technical Staff — engineers who build the systems that make LLM inference...  ...engineers now. About the company One-liner: Building the infrastructure that makes LLM inference fast — and putting the engineers... 
    H1b
    Work at office

    Simplify

    San Francisco, CA
    3 days ago
  • $120k - $300k

     ...(Seed) · Industry: FinTech The Role A backend-leaning Member of Technical Staff building the end-to-end systems that power the client's production AI compliance workflows — high-performance infrastructure, reliability, and backend architecture supporting mission-critical... 
    Full time
    H1b
    Visa sponsorship

    David Joseph & Company

    San Francisco, CA
    18 days ago
  • $250k

     ...· 1–10 people (Seed) · Industry: AI Tools The Role A Member of Technical Staff who can handle everything from modeling to systems to product...  ...Familiarity with data pipelines, APIs, and cloud infrastructure (AWS, GCP) Experience with machine-learning models or data... 
    Full time
    H1b
    Visa sponsorship

    David Joseph & Company

    San Francisco, CA
    17 days ago
  • $220k - $250k

     ...company focused on personalizing patient care, is hiring a Member of Technical Staff to join their team remotely. The successful candidate...  ...imaging technologies is a plus. ~Comfortable operating across infrastructure, backend engineering and product-focused workflows. ~... 
    Full time
    Remote work

    Alldus International Consulting Ltd

    San Francisco, CA
    more than 2 months ago
  •  ...settlement, and the industry's leading security infrastructure. Home to Anchorage Digital Bank N.A.,...  ...your capabilities in 4 major areas: Technical Skills: Participate in task...  ...ecosystem. As a diverse team of more than 600 members, we are united in one common goal:... 
    Full time

    Anchorage Digital

    San Francisco, CA
    27 days ago
  •  ...disbursement, and credit partners, and the compliance and reporting infrastructure that the banking partner and the regulators depend on....  ...'t a quality bar. It's the product. Why the title is Member of Technical Staff Because they'd rather hire the person than fill the box.... 
    Work at office
    Remote work
    Visa sponsorship
    Flexible hours

    EQL Tech

    San Francisco, CA
    14 days ago
  • $150k

    Join Amazon's Frontier AI & Robotics team as a Member of Technical Staff, this Technical Program Manager will become the driving force behind...  ...and practical impact. We leverage Amazon's computational infrastructure and rich real-world datasets to train and deploy state-of... 
    Local area
    Day shift

    Amazon

    San Francisco, CA
    4 days ago
  •  ...engineering skills across the stack: backend systems, APIs, cloud infrastructure (GCP, AWS, or Azure), and modern frontend frameworks...  ...building demos under time pressure, and representing the company technically Background in scalable model serving & deployment... 

    Kindredventures

    San Francisco, CA
    4 days ago
  •  ...and Faraz left AWS and Microsoft, where they built critical infrastructure for MSFT Copilot and AWS Bedrock to start Bluejay. Bluejay builds...  ...senior engineers with 2+ YOE who want to play a pivotal technical role in Bluejay’s team. We want senior, experienced engineers... 
    Work at office

    Blue Jay Inc.

    San Francisco, CA
    3 days ago
  •  ...might spend one month on a training run, the next on evaluation infrastructure, and the next embedded with scientists to understand where...  ...experimentation through production deployment and iteration. Act as a technical resource within the team, mentoring colleagues and raising... 
    Live in

    Autopoiesis Sciences

    San Francisco, CA
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Member of Technical Staff - Infrastructure. Be the first to apply!