Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Member of Technical Staff - Infrastructure

$150k - $300k

Phylo

About Phylo Phylo is an applied research lab building agentic intelligence to accelerate discovery for every biomedical scientist. We believe AI agents will fundamentally transform how biomedical research is done, enabling faster and more systematic scientific progress. Our growing team brings together world-class researchers and engineers across AI and biology. Backed by a $13.5M seed round led by a16z, Menlo Ventures, and Anthropic, and advised by Nobel Prize laureate and pioneering biologists, Phylo is building the next generation of AI systems for the life sciences. About The Role We’re looking for an Infrastructure Engineer to build, operate, and scale the deployment foundations for Phylo’s enterprise AI platform. This role is focused on the systems that let Phylo run reliably in real‑world customer environments: cloud infrastructure, Kubernetes, secure single‑tenant deployments, observability, networking, storage, and operational workflows. You’ll help bring Phylo’s agentic AI platform into enterprise pharma, biotech, and research environments where security, reliability, data isolation, and deployment discipline matter deeply. You’ll work closely with engineering, ML, science, and customer‑facing teams to make Phylo easy to deploy, monitor, support, and scale across cloud and customer‑managed environments. What You’ll Work On Design, build, and operate infrastructure for Phylo’s enterprise deployments, including single‑tenant and customer‑hosted environments. Build deployment systems for cloud‑native and enterprise environments, own Kubernetes‑based infrastructure for Phylo services, sandboxed agent execution, compute workloads, storage mounts, networking, and observability. Support infrastructure for scientific and computational workloads, including HPC‑adjacent workflows, bioinformatics tools, batch execution, GPU/CPU compute, and large‑scale file/data movement. Work with customer‑facing teams to support enterprise deployment planning, debugging, reliability reviews, and production operations. Help define the long‑term architecture for deploying Phylo into pharma, biotech, academic, and research environments. Requirements 2+ years of industry experience in infrastructure engineering, DevOps, SRE, platform engineering, cloud engineering, or a similar role. Strong hands‑on experience with Kubernetes in production. Experience deploying and operating systems on AWS, GCP or Azure. Experience with infrastructure‑as‑code tools such as Terraform, Pulumi, CDK, or similar. Strong understanding of networking, IAM, VPCs, load balancers, DNS, certificates, secrets management, and cloud security fundamentals. Experience building CI/CD pipelines, deployment automation, environment provisioning, and operational tooling. Nice to Haves Experience deploying enterprise SaaS into single‑tenant, customer‑hosted, VPC‑isolated, or regulated environments. Experience building or maintaining R&D infrastructure in pharma, biotech, academic research, or life sciences organizations. Experience with HPC, bioinformatics infrastructure, scientific computing, workflow engines, or batch schedulers. Experience with tools or systems such as Nextflow, Snakemake, Cromwell, Slurm, AWS Batch, EKS, ECS, FSx, Lustre, S3, or distributed filesystems. Experience with secure sandboxing or isolated execution environments such as gVisor, Kata Containers, Firecracker, or Kubernetes sandboxing. Experience supporting GPU‑enabled workloads, large‑scale data processing, or scientific compute clusters. Experience with enterprise identity, SSO, audit logging, compliance controls, customer networking, VPNs, private connectivity, or data residency requirements. Experience working directly with enterprise customers during deployment, onboarding, debugging, or production support. Why Join Us? Competitive salary and equity share in building the future of biomedical discovery Full medical, dental, and vision coverage, including free therapy sessions and eyewear stipend 401(k) to help you build long‑term financial security (US only) Unlimited PTO to recharge when you need it (US only) Lunch and snacks when you’re in the office Regular team offsites and company events A culture of excellence and speed - we move fast, think big, and support each other every step of the way Your work will directly impact our mission to 100X biomedical discoveries through AI Compensation Range: CA$150K - CA$300K #J-18808-Ljbffr

Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Member of Technical Staff - Infrastructure in South San Francisco, CA vacancy
  •  ...enterprises that integrate LLMs into their products. The team is 5 people with a research and product focus. As a Member of Technical Staff on our infrastructure team, you'll own the cloud systems that serve our compression API end-to-end. You'd get to build global low-... 
    Suggested
    Visa sponsorship

    The Token Company

    San Francisco, CA
    16 hours ago
  • $300k

    Member of Technical Staff - RL Infrastructure About V max V max is an applied research lab developing AI capable of open-ended learning. We are building systems to exceed humans in all capacities by optimising beyond the local maxima of learning from human expertise. About... 
    Suggested
    Work at office
    Local area

    Vmax

    San Francisco, CA
    2 days ago
  •  ...observe their code. We are responsible for designing, building, and scaling core infrastructure that powers a high-volume data platform for AI applications. We are looking for team members who love building enabling systems that empower our engineers and power our rapidly... 
    Suggested
    Work at office

    LlamaIndex

    San Francisco, CA
    1 day ago
  •  ...Plato is an applied research lab building the foundational infrastructure to train specialized AI agents. We turn real-world data...  ..., and iteration feel like one seamless system. As a Member of Technical Staff, Infrastructure / DevOps, you will own the systems that make... 
    Suggested

    Plato

    San Francisco, CA
    1 day ago
  •  ...DeepMind, OpenAI, Google Brain, Meta, Character.AI, Anthropic and beyond. Role Overview Reflection.AI is looking for a Member of Technical Staff - Infrastructure Security to secure our geographically diverse multi-cloud Kubernetes and cloud environments. In this role, you’ll... 
    Suggested
    Full time
    Relocation package

    aijoblist

    San Francisco, CA
    16 hours ago
  • $120k - $250k

    Job Title Member of Technical Staff, Infrastructure Salary $120K - $250K + Equity Company Description The Token Company is a $12M seed‑stage startup backed by First Round Capital, NEA, and YC, building specialized machine learning models to compress LLM inputs. By identifying... 
    Visa sponsorship

    Jack & Jill

    San Francisco, CA
    16 hours ago
  • Member of Technical Staff - Infrastructure Security We're partnering with a frontier AI research company that is building next-generation open-weight foundation models with the mission of making advanced AI broadly accessible. Their team includes researchers, engineers... 

    Xcede

    San Francisco, CA
    16 hours ago
  • # Founding Member of Technical Staff, AI Infrastructure**Location:** San Francisco / Bay Area preferred. Remote exceptional for the right person.We look for fast learners with high agency, AI-native workflows, clear technical communication, and evidence-backed judgment... 
    Full time
    Remote work

    Touchdown Labs, Inc.

    San Francisco, CA
    16 hours ago
  • $256k - $276k

    Member of Technical Staff, AI Platform & Architecture Postman is the world’s leading API platform, used by more than 40 million developers and...  ...at postman.com. As a Member of Technical Staff on AI Infrastructure, you will build and maintain the foundational systems and... 
    Work at office
    Flexible hours
    3 days per week

    Postman

    San Francisco, CA
    4 days ago
  • $256k - $276k

    Opportunity As a Member of Technical Staff on AI Infrastructure, you will build and maintain the foundational systems and distributed infrastructure that power AI model post training, inference, and data pipelines. Responsibilities Design and implement large-scale, distributed... 
    Flexible hours

    Postman

    San Francisco, CA
    4 days ago
  • Member of Technical Staff, ML Infrastructure & Inference Overview We are a cutting-edge AI infrastructure company building a scalable cloud platform designed for next-generation machine learning workloads ($80M series A). As AI systems continue to grow in complexity,... 

    Acceler8 Talent

    San Francisco, CA
    1 day ago
  •  ...Infrastructure / Cluster Engineer Gimlet is building the next generation of AI infrastructure: large-scale AI datacenters and the orchestration platform that coordinates them. The future of AI will require vastly more compute than exists today. But as AI workloads... 

    Gimlet Labs

    San Francisco, CA
    2 days ago
  •  ...agent for enterprise computer automation. Our developer platform writes, tests, and maintains automation code on fully‑managed infrastructure – cutting dev time by 90%. We’re starting with healthcare, where legacy systems make reliable automation a genuinely hard problem... 
    Immediate start
    Remote work

    CloudCruise

    San Francisco, CA
    16 hours ago
  •  ...when people take ownership, grow together, and share both the challenges and the wins. What you'll do Build the supercomputing infrastructure that runs our agents. Our agents tackle long-horizon, high-performance workloads, and you'll design the cloud compute, distributed... 
    Work at office
    Remote work
    Flexible hours

    asari.ai

    San Francisco, CA
    1 day ago
  • $150k - $300k

    Building Open Superintelligence Infrastructure Prime Intellect is building the open superintelligence stack - from frontier agentic models...  ...Solutions Architect for GPU Infrastructure, you'll be the technical expert who transforms customer requirements into production‑ready... 

    Prime Intellect

    San Francisco, CA
    16 hours ago
  • $350k

     ...training our own models end-to-end. Our work spans areas such as model training, reinforcement learning, reasoning systems, and infrastructure for large-scale experiments. Our team includes researchers and engineers from Anthropic, Google DeepMind, xAI, OpenAI,... 

    Mirendil

    San Francisco, CA
    1 day ago
  •  .... Successful candidates typically come from staff or principal-level roles and are recognized for establishing technical direction, leading large-scale initiatives,...  ...teams use to right‑size space and budgets. This infrastructure already powers 16,000 workplaces and 9,000+... 
    Work at office
    Local area
    Monday to Thursday

    Envoy Inc.

    San Francisco, CA
    4 days ago
  • About Mandolin Nearly every disease will become treatable in our lifetimes. Mandolin is laying the clinical and financial infrastructure to get groundbreaking treatments to patients faster, powered by AI agents. Mandolin partners closely with the largest healthcare institutions... 
    Local area

    Mandolin

    San Francisco, CA
    4 days ago
  •  ...Kubernetes, Terraform, Istio, Pulumi, and AWS Cloud, to automate our infrastructure and deliver reliable applications efficiently. By using...  ...and Prometheus. Strong communication, analytical, and technical leadership skills. Preferred Skills Experience working in a... 
    Work at office
    Local area
    Monday to Thursday

    Envoy

    San Francisco, CA
    1 day ago
  • $150k - $265k

     ...human again. Mission We're building the platform for the future of voice technology. Our market edge is extensible, reliable infrastructure designed for the full complexity of voice interactions. 18 months, 150k developers, adding 1000 every day. Give it a try here... 
    Full time
    Shift work

    Vapi

    San Francisco, CA
    4 days ago
  •  ...Horowitz, GIC, Goldman Sachs, KKR, Visa, and others. Technical Skills Develop and maintain infrastructure that powers digital asset custody, trading, staking,...  ...to solve problems, and assist or teach other team members when possible. You may be a fit for this role if you... 
    Worldwide

    Crypto Pro Network

    San Francisco, CA
    16 hours ago
  • $200k - $350k

     ...role in designing, scaling, and operating the core platform infrastructure that powers autonomous scientific discovery. Your primary focus...  ...Edison Scientific, engineering at the senior level is about technical ownership and leverage - understanding how complex systems interact... 
    Work at office

    Edison Scientific

    San Francisco, CA
    3 days ago
  •  ...users create characters, worlds, stories, and relationships with AI, and making that feel fast, reliable, and alive takes serious infrastructure. We are looking for an engineer who wants to help own that whole stack. We run more of our own than most companies our size.... 

    janitorAI

    San Francisco, CA
    16 hours ago
  •  ...You'll Pioneer You’ll create the data systems that make frontier research and the largest training runs possible. It's building infrastructure at a scale where billion-image datasets are normal and where video processing pipelines need to run across thousands of GPUs.... 
    Worldwide

    Black Forest Labs

    San Francisco, CA
    2 days ago
  •  ...building the foundational software and infrastructure that everything else depends on. This is...  ...growth. What We Look For Senior to staff-level experience in software engineering...  ...source projects or other publicly visible technical work. Comfort owning ambiguous, high-... 

    Dimensional Inc.

    San Francisco, CA
    16 hours ago
  • Role We seek experienced engineers to architect and scale the core infrastructure behind distributed training pipelines and petabyte-scale data catalogs. You\'ll work directly with researchers to accelerate experiments, develop new datasets, improve infrastructure efficiency... 

    Inception

    San Francisco, CA
    1 day ago
  • $150k

    Description Amazon’s Frontier AI & Robotics (FAR) team is seeking a Member of Technical Staff, Infrastructure to build and scale the foundational systems that power our robotics research and development platform. In this role, you will design and operate the distributed... 
    Local area

    Amazon Science

    San Francisco, CA
    4 days ago
  • $140k - $200k

     ...Member of Technical Staff Harper is an AI-native commercial insurance company in San Francisco. We're not bolting AI onto insurance - we...  ...building software, full-stack by instinct (frontend, backend, infrastructure). ~ You've shipped AI to production - real systems... 
    Work at office
    Relocation

    Harper Group

    San Francisco, CA
    4 days ago
  •  ...Member Of Technical Staff We're looking for a member of technical staff to build and deploy production-grade AI systems. In this role, you...  ...Familiarity with data pipelines, APIs, and cloud infrastructure (AWS, GCP) Experience working with machine learning models... 

    Eragon

    San Francisco, CA
    1 day ago
  •  ...Member of Technical Staff @ Lotus AI Lotus AI is a groundbreaking primary care app that integrates your medical records, AI, and real doctors...  ...with system refactors, schema migrations, and data infrastructure simplification Familiarity with PostgreSQL (including... 

    Lotus Health

    San Francisco, CA
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Member of Technical Staff - Infrastructure. Be the first to apply!