Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Automation Engineer - Production Chemistry

$110k - $130k

Satomic

About Satomic

Satomic's mission is to close the gap from idea to molecule with faster navigation of chemical space. We are building an automated chemistry platform that integrates laboratory robotics, software, and AI to transform small-molecule synthesis and drug discovery.

This role is critical to Satomic's mission of closing the gap from idea to molecule by building the automation systems that reliably synthesize and route customer molecules through our production platform with speed and reliability, enabling our partners to explore chemical space- and advance their programs - faster. Satomic is building an API to atoms, and this role owns the orchestration and physical automation behind that API - ensuring requests are executed cleanly on our synthesis systems with a frictionless experience for our own operators and partners.

About the Role

This is a senior individual contributor role building the preparative liquid handling platform at the center of Satomic's chemistry operations. You will develop and own the Venus methods and instrument integrations that move samples through the production chemistry pipeline, partnering closely with chemists and the software team to ship workflows that run reliably in production.

The right candidate has deep Hamilton experience and strong hardware instincts. You will integrate peripherals into the StarV workcell, develop liquid handling methods across the production chemistry pipeline, define handoff points to downstream purification and analytical workflows, and work with the software team to ensure runs produce traceable data. You will also provide troubleshooting support for the production team and build out workflows that keep batch runs moving as the platform grows.

This is a hands-on, lab-based role for someone who takes pride in building automation the whole team can depend on and who can navigate the intersection of instrumentation, method development, and software integration.

Technologies and systems you may work with include:

  • Liquid handling robotics (e.g., Hamilton liquid handlers)
  • Automation control software (e.g., VENUS)
  • Laboratory instrumentation such as incubators, sample management systems, de-cappers, and analytical systems
  • Internal software systems used for experiment orchestration and data capture
  • Automation validation and testing frameworks used to ensure reliability of automated workflows
Expected Outcomes:

By day 30, you will have:
  • Developed a working understanding of the current chemistry workflows and what the platform needs to support for scale up
  • Delivered at least one Venus method or integration into production, with documentation and a validated operating procedure
  • Mapped remaining open work against company milestones and identified the critical path with timelines the team can align on
By 90 days, you will have:
  • Integrated at least two peripheral instruments into the StarV workflow and validated them in production
  • Delivered the core Venus methods and instrument integrations needed to get Satomic's production-scale chemistry workflows running and performed necessary validation testing to meet user requirements
  • Worked with the software team to ensure methods are integrated with sample logging and tracking systems
  • Written operating procedures for completed integrations and methods
By year 1, you will have:
  • Integrated the full instrument suite required to support current chemistry programs
  • Established a method development process that lets new chemistry be onboarded efficiently as scope grows
  • Trained at least one other team member on platform operation using documentation you authored
By year 5, you will have:
  • Built integrations that span multiple workcells that allow for overnight, unattended operation
  • Become the go-to reference for Hamilton integrations and scheduling problems at Satomic
  • Made the automation platform a core part of how Satomic runs chemistry at scale
What You Will Own
  • Method development for production workflows, such as integration, scheduling, and batch processing
  • Instrument procurement, installation, and hardware configuration
  • Troubleshooting support for the production team and building workflows that keep batch runs moving
  • Operating procedures and documentation for production methods
Qualifications
  • 5+ years of experience in laboratory automation engineering with demonstrated ownership of method development, validation, and production deployment
  • Prior experience integrating accessory instrumentation with Hamilton on Venus is required. You must be able to write, debug, and extend methods independently
  • Prior Hamilton service training is a plus
  • Strong hardware and integration background
  • Experience installing and commissioning lab instruments
  • Comfortable working through integration problems across hardware, software, and instrumentation
  • Able to document methods clearly and work closely with chemists to understand what needs to be automated
What this Role Is (and Is Not)

This role is:
  • A senior individual contributor to own and support building out the automated production chemistry pipeline in a laboratory setting
  • Focused on method reliability, liquid handling systems, and building workflows that scale toward continuous operation
This role is not:
  • For a system with PLC automation or industrial-scale chemical manufacturing
  • A role where automation methods are handed to you fully defined and ready to execute.
  • A software developer, data science, or assay scientist position
Overview of Satomic's Interview Process
  • Phone screen (15 minutes): A brief introductory call to discuss the role and answer questions
  • Core Interviews (3 x 45 minutes): the hiring manager will coordinate a block where you can have three 45 minute interviews back to back with different members of the Satomic team, who will ask questions about your past experience and fit for the role
  • Take-home assignment: A scoped engineering problem representative of the work at Satomic, completed on your own time
  • Final round: A technical review of your take-home submission, and presentation of prior work to the interview panel to understand how you work, how you think, and how you collaborate across disciplines

Why Join Satomic?

Join a team tackling frontier challenges in chemistry and the biggest bottleneck in drug discovery- an opportunity to shape not just Satomic, but the future of how molecules are discovered and made.

Diversity & Inclusion

We know there's a serious lack of diversity in our industry, and that needs to change. At Satomic, we're committed to helping drive that change. Our culture is built on inclusion, humility, humanity, and ingenuity- values that guide how we work with one another and how we approach the challenges of scaling science. We believe that bringing together people with diverse perspectives, experiences, and ways of thinking is not just the right thing to do, but makes us stronger: we want every member of our team to feel they belong and can do the best work of their career here.

Our mission is to close the gap from idea to molecule. That mission carries responsibility: the chemistry we enable can accelerate access to life-changing medicines and technologies, but it can also pose risks if used carelessly. We're not agnostic to how our platform is applied-we care deeply about ensuring it is used for good. Building a team of diverse and thoughtful voices gives us the best chance of delivering a platform that not only advances the future of chemistry and drug discovery, but does so responsibly and with lasting positive impact on our world.

Compensation

This role offers a base salary of $110,000 - $130,000, along with meaningful equity ownership and competitive benefits.

We are an early-stage company and design offers to balance cash compensation and long-term ownership. The salary range above reflects base pay only, and we work with candidates to build a package that aligns with their preferences.

Final offers are based on a candidate's experience and expected impact. For candidates exceptionally aligned with the role we are comfortable positioning offers toward the top of this range and beyond.
Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Senior Automation Engineer - Production Chemistry in Nacogdoches, TX vacancy
  • $93.8k - $174.2k

     ...Novartis San Diego is seeking a technologically oriented Senior Automation Engineer to join our Advanced Automation Technologies group. The primary...  ...systems for screening, compound handling, automated chemistry, or related applications. Recent PhD's with relevant experience... 
    Senior

    Novartis Group Companies

    Nacogdoches, TX
    5 days ago
  • $145.25k - $183.75k

     ...Lytx is building a next-generation product platform combining a cloud-native AWS backend with embedded IoT hardware, including...  ...and smart cameras. We are looking for a skilled Senior QA Automation Engineer to join a newly formed QA team supporting Lytx's cloud and... 
    Senior
    Temporary work
    Local area
    Flexible hours

    Lytx

    Nacogdoches, TX
    3 days ago
  • $124k - $186k

     ...Job Description We are seeking a senior, hands-on Senior Automation Engineer to help define, evolve, and execute the technical vision for laboratory...  ...close to the lab and accountable for reliability in production. You translate long-term vision into pragmatic... 
    Senior
    Summer work
    Flexible hours

    Vertex Pharmaceuticals

    Nacogdoches, TX
    1 day ago
  • Job Title Responsibilities: Provide hands-on support focused on stabilizing critical utilities controls ahead of an end of May milestone. Execute Siemens Desigo programming/configuration updates and point modifications to support operational readiness. Perform...
    Senior

    Katalyst HealthCares & Life Sciences

    Nacogdoches, TX
    1 day ago
  • $100k - $165k

     ...A leading technology firm in San Diego seeks a Senior Software Test Engineer to work in state-of-the-art labs verifying and validating advanced...  ...testing integrated wireless communication systems, designing automation capabilities, and collaborating with software developers... 
    Senior

    TrellisWare Technologies

    Nacogdoches, TX
    3 days ago
  • $100k - $165k

     ...A tech company specializing in wireless communications is seeking a Senior Software Test Engineer in San Diego, California. You will verify and validate advanced radio systems, design automation capabilities, and ensure reliable software builds. The role requires a Bachelor... 
    Senior

    TrellisWare Technologies

    Nacogdoches, TX
    3 days ago
  • $125k - $165k

     ...A technology solutions company in San Diego is looking for a Mid-Level Network Engineer to support Navy Tactical Networks. Responsibilities include designing and configuring network infrastructure, troubleshooting issues, and implementing security measures. The ideal... 
    Senior
    Full time

    Sapient Logic LLC

    Nacogdoches, TX
    3 days ago
  • $95k - $200k

     ...civilians with intelligent systems. Its products include the V-BAT and X-BAT aircraft, Hivemind...  ...years. We're looking for a software engineer, well versed in development and testing,...  ...V-BAT's test operations, specifically automation capabilities and tools used to test... 
    Senior
    Full time
    Temporary work
    Part time
    Internship
    Worldwide

    Shield AI

    Nacogdoches, TX
    1 day ago
  •  ...Fremont, CA servicing clients nationwide. We provide services in IT, Telecom, Finance & Accounting and Engineering categories. Designation: Test Automation Engineer Location: San Diego, CA 92130 2 days/week (1st day must start from office) Job Type: Contract... 
    Contract work
    Work at office
    Immediate start
    2 days per week

    Exaways Corporation

    Nacogdoches, TX
    1 day ago
  • $86.9k - $198k

     ...Automation Engineer The Opportunity: We are seeking an experienced automation engineer for...  ...and Ansible Automation Platform in a production environment and developing reusable Ansible...  ...~ Experience operating as a senior engineer or technical lead in an enterprise... 
    Full time
    Contract work
    Part time
    Work at office
    Local area
    Remote work

    BOOZ, ALLEN & HAMILTON, INC.

    Nacogdoches, TX
    4 days ago
  •  ...Automation Engineer A prominent company in the pharmaceutical and wellness industry is seeking...  ...Automation Engineer to enhance their production capabilities. This role focuses on leading...  ...: 140 - 165k The role reports to a senior engineering leader and does not... 

    Talentry LLC

    Nacogdoches, TX
    7 days ago
  • $93.36k - $107.28k

     ...designing, specifying, maintaining, diagnosing, repairing, and upgrading automated control systems and instrumentation, including completion of GMP-related documentation. The Automation Engineer III will lead technical assessments and upgrade projects for automated control... 
    Full time
    Work at office
    Flexible hours

    PCI Pharma Services

    Nacogdoches, TX
    8 days ago
  •  ...A leading technology firm is seeking an experienced engineer in San Diego to manage the complete verification lifecycle for digital power IPs. The ideal candidate has a Bachelor's degree in Engineering or Science and over four years of experience in ASIC design and verification... 
    Senior

    Qualcomm

    Nacogdoches, TX
    3 days ago
  • $165k - $225k

     ...fast-paced and passionate team as a Senior Principal Robotics Process Engineer. As we scale, you will be...  ...and alignment methods to support product roadmap. Perform alignment system...  ...Demonstrated successful execution of automated test or component alignment using... 
    Senior
    Local area
    Flexible hours

    Monarch Quantum, Inc.

    Nacogdoches, TX
    4 days ago
  • $90k - $115k

     ...Automation Support Engineer II Salary Range $90,000.00 - $115,000.00 Salary/year HighRes is a Beverly, Massachusetts–based life sciences lab automation company that partners with biotech, pharma, and research organizations to implement intelligent laboratory workflows... 
    Work experience placement
    Work at office
    Remote work

    HighRes Biosolutions

    Nacogdoches, TX
    1 day ago
  • $140k - $160k

     ...silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger...  ...the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics... 
    Senior
    Contract work
    Worldwide

    Arrowhead Pharmaceuticals, Inc.

    Nacogdoches, TX
    3 days ago
  • $75k - $125k

     ...Automation Validation Engineer JSat Automation is hiring an Automation Validation Engineer for their San Diego Office. This position may travel up to 40% to client sites. This Engineer will be responsible for the following: Design and develop manufacturing control... 
    Work at office

    E Tech Group

    Nacogdoches, TX
    1 day ago
  •  ...Perform activities and operations related to quality assurance for the production QA team Ensure that products meet or exceed quality standards set forth by the team Develop and run automated test cases (functional, performance and system regression tests) Participate... 
    Work experience placement
    Flexible hours

    Black Swan Search

    Nacogdoches, TX
    1 day ago
  •  ...Intel. Automation Engineer - Data Sci. & Analytics UC San Diego Health is on a journey to build...  ...closely with the Intelligent Automation Product Manager to translate operational use...  ...Health Information Services. This is a senior technical role that requires strong... 

    UC San Diego

    Nacogdoches, TX
    8 hours ago
  •  ...A technology company in San Diego is seeking a highly skilled DevOps Developer II to support automation in patching and system maintenance. This role requires strong scripting skills in bash and experience with RHEL. The ideal candidate will work collaboratively with... 

    Corelation

    Nacogdoches, TX
    3 days ago
  • $115k - $140k

     ...A digital agriculture solutions provider in San Diego is seeking a Senior Software Engineer to leverage AI technology in developing innovative solutions for the agriculture industry. The role involves enhancing user experiences, advocating for development best practices... 
    Senior

    PickTrace

    Nacogdoches, TX
    3 days ago
  •  ...Electrical Engineer Mount Indie is seeking an experienced Electrical Engineer with deep expertise in power systems design and integration...  ...reviews, prototype integration, qualification testing, and production transition Work with suppliers and manufacturing partners... 
    Senior

    Mount Indie

    Nacogdoches, TX
    3 days ago
  •  ...000 companies to tap into global manufacturing capacity. Xometry is seeking an experienced and charismatic Senior Solutions Engineer - Automotive Production for a critical customer-facing role. This role supports Sales by providing perspective, feedback, and sharing... 
    Senior
    Work at office
    Remote work

    Xometry

    Nacogdoches, TX
    8 days ago
  •  ...A technology firm in California is seeking an Infrastructure & Automation Engineer to design, maintain, and automate systems and networks. Ideal candidates will have hands-on experience with Linux, Docker, and Ansible, ensuring reliability and scalability across their... 

    Virewirx, Inc.

    Nacogdoches, TX
    3 days ago
  •  ...A leading engineering company in San Diego is seeking a Software Engineer specializing in automation and integration solutions. The ideal candidate will have extensive experience in developing backend services using Python, with opportunities to work on cutting-edge technologies... 
    Full time
    Contract work

    OSI Engineering

    Nacogdoches, TX
    3 days ago
  •  ...solutions designed with the operator in mind and the right amount of engineering rigor? If so – we want to hear from you! This role will...  ...reviews, prototype integration, qualification testing, and production transition Work with suppliers and manufacturing partners... 
    Senior

    Fuse Integration

    Nacogdoches, TX
    4 days ago
  • $85k - $125k

     ...A cutting-edge technology company in San Diego is seeking a Robotics Process Engineer 2. This dynamic role involves both independent and team work in a startup environment, focusing on building engineering practices. Candidates should have a Bachelor's degree in mechanical... 

    Monarch Quantum, Inc.

    Nacogdoches, TX
    3 days ago
  • $106.8k - $194.8k

     ...help to build a better working world. WAF Operations Solution Engineer PRACTICE DESCRIPTION: As a WAF Operations Solution...  ...leveraging your experience with various WAF solutions to implement and automate security measures. KEY RESPONSIBILITIES: Configure,... 
    Senior
    Summer holiday
    Flexible hours

    EY

    Nacogdoches, TX
    5 days ago
  • $106.5k - $197.5k

     ...domains in the interest of national security. Job Title: Senior Specialist, Electrical Engineer - Power Supply Design Job Code: 37911 Job Location...  ...design and development to work on Telemetry and RF products. This requirement includes Fly back and Feed forward DC... 
    Senior
    Local area
    Relocation
    Relocation package
    Flexible hours

    L3Harris

    Nacogdoches, TX
    2 days ago
  • $155.66k - $225.16k

     ...world’s knowledge. To do so, we have two knowledge sharing products: Quora : a global knowledge sharing platform with over 4...  .... About the Team and Role: We’re hiring our first AI Automation Engineer to lead how we apply AI internally across the company. This... 
    Remote job
    Full time
    Shift work

    Quora

    Nacogdoches, TX
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Automation Engineer - Production Chemistry. Be the first to apply!