Senior Director - Clinical Tech Design and Operations

Job ID: R-108576Company: LillyLocation: Indianapolis, Indiana, United States of AmericaJob Type: Full TimeCategory: Information TechnologyPosted Date: 2026-07-27At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. Position Summary This M3 leader directs the technology strategy and delivery for Clinical Design and Operations, leading through subordinate managers and holding leadership responsibility for a portfolio of clinical technology capabilities. The role requires technical knowledge and cross-functional leadership, an understanding of how clinical design and operations interacts with other business areas to achieve functional objectives, and the judgment to make decisions with significant impact on the function. Consistent with Lilly's technology direction, this leader is technically fluent and deeply AI-aware—championing AI and agentic adoption, resolving complex technical challenges, and ensuring teams build modern, compliant, high-value solutions. Key ResponsibilitiesLead the Clinical Design and Operations technology portfolio through subordinate managers, developing business-area plans and managing resources to meet financial and operational objectives. Set and drive the technical and AI strategy, championing AI, agentic workflows, and intelligent automation to raise capability and value. Evaluate and resolve complex business, operational, and technical challenges spanning multiple clinical capabilities. Make decisions, guided by functional strategy, that significantly impact the clinical design and operations function. Build collaborative relationships and influence internal and external partners across multiple business areas to align on technology direction. Ensure portfolio solutions meet GxP, security, and quality requirements from design through delivery. Maintain technical depth sufficient to guide architecture, engineering, and AI-adoption decisions and to challenge solution trade-offs. Build technical and AI capability across managers and engineers through knowledge-sharing and upskilling. Forecast and manage resources to meet operational and financial objectives across the portfolio. Represent clinical design and operations technology in governance forums, contributing to standards and investment decisions. Basic Qualifications Bachelor's degree in Computer Science, Software Engineering, Information Technology or related field.Minimum 8+ years' experience in technology delivery or engineering leadership, including leadership through subordinate managers. Experience delivering within Agile/SAFe environments and product-led operating models. Strong stakeholder management, able to influence across multiple business areas and with external partners. Preferred Qualifications Technical knowledge and cross-functional leadership, with understanding of how clinical design and operations interacts with other business areas. Hands-on experience leveraging AI in day-to-day delivery and championing its adoption across teams. Proven ability to evaluate and resolve complex business, operational, and technical problems. Experience managing budgets and resources to meet financial and operational objectives. Experience in clinical development, Good Clinical Practice (GCP), or a regulated (GxP) environment within pharmaceutical, biotech, or healthcare. Advanced degree in a technical, scientific, or business discipline. Working knowledge of AI/ML and agentic capabilities and their applicability to clinical operations. Familiarity with enterprise/clinical architecture and platform strategy. Experience operating within a formal IT governance or product operating model. Relevant leadership, Agile/SAFe, cloud, or AI certifications. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form () for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (View email address on click.appcast.io), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is$157,500 - $231,000Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.#WeAreLillySkillsclinical design and operationstechnology strategyai strategygxp complianceagentic workflowsintelligent automationstakeholder managementcross-functional leadershipportfolio managementresource managementbudget managementclinical developmentgood clinical practiceenterprise architecturecloud computingagilesafeit governanceknowledge sharingupskillingai/mlplatform strategyleadership certificationproduct operating model