Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Head Rare Diseases, US Medical Affairs (Cambridge, MA)

$303k - $428k
Full-time

Biogen

This job is with Biogen, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

About This Role
The Head of Rare Diseases, US Medical is a critical leadership role within the US Medical organization, accountable for the strategic direction and execution of medical affairs activities across the Rare Diseases portfolio. This includes both marketed and pipeline assets in Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), and Friedreich's Ataxia (FA), among other emerging indications. The portfolio spans early access programs, lifecycle management studies, and multiple launched therapies, each supporting patients with high unmet needs and representing major growth opportunities for Biogen.

As a key member of the North America Medical Leadership Team, this leader will report to the Head of Medical, North America. They will oversee a cross-functional medical team including Medical Directors, Field Director, and Medical Science Liaisons (MSLs), while collaborating closely with Global Medical teams, Regulatory, US Commercial, Market Access, and Value & Evidence Generation partners. This individual will represent the Rare Diseases medical perspective across senior leadership forums and ensure that the strategic priorities of the therapeutic area are aligned with broader corporate goals, all while advancing scientific knowledge, clinical impact, and patient outcomes.

What You'll Do

  • Lead the development and execution of the US Medical strategy across the Rare Diseases portfolio, encompassing multiple marketed products and late-stage development assets.

  • Serve as the primary medical point of contact for Rare Diseases across US Commercial, Market Access, Global Medical, and Regulatory organizations.

  • Oversee field medical strategy and operations for the Rare Diseases franchise, including Field Director and MSL teams.

  • Provide leadership and strategic oversight for scientific content development, external stakeholder engagement, congress strategy, publications, and advisory boards.

  • Ensure medical input is embedded in key cross-functional activities including lifecycle management, launch planning, and field enablement.

  • Champion the integration of patient and HCP insights into strategic and tactical planning, ensuring a data-driven and customer-centric approach to decision-making.

  • Lead with a performance-driven mindset, promoting accountability, innovation, and excellence across the Rare Diseases medical team.

  • Mentor and develop medical affairs talent through intentional coaching, career path planning, and succession development.

  • Represent Rare Diseases in cross-functional governance, promotional review committees, and compliance processes, ensuring rigorous execution and alignment with regulatory expectations.

  • Manage and oversee the Rare Diseases medical budget, ensuring efficient resource utilization and investment in areas of highest impact.

Who You Are
You are a purpose-driven and strategic medical leader with a passion for advancing care in rare and complex diseases. You have experience leading medical teams, building collaborative relationships across stakeholders, and delivering meaningful impact for patients and the business. You thrive in complexity, operate with integrity, and create environments where high performance and empathy can co-exist.

Qualifications

Required Skills

  • MD, PhD, PharmD, or DNP in a clinical or scientific discipline.

  • 12+ years of Medical Affairs experience in roles with increasing responsibility and accountability for medical affairs planning & tactical execution.

  • 5+ years of experience leading Medical Affairs teams across multiple products or within complex therapeutic areas.

  • Demonstrated experience in developing and executing medical strategies for both marketed and pipeline assets.

  • Deep understanding of medical engagement, regulatory environment, field medical operations, and scientific communication.

Preferred Skills

  • Experience in Rare Diseases or Neurology strongly preferred.

  • Proven success launching and supporting multiple products within a portfolio-based medical model.

  • Comfort working in a fast-paced, matrixed environment with high strategic visibility.

  • Track record of building and leading high-performing teams with a focus on talent development and inclusive leadership.



 

Job Level: Management


Additional Information

The base compensation range for this role is: $303,000.00-$428,000.00


Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance. 

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees' and their families physical, financial, emotional, and social well-being ; including, but not limited to:

  • Medical, Dental, Vision, & Life insurances
  • Fitness & Wellness programs including a fitness reimbursement 
  • Short- and Long-Term Disability insurance
  • A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
  • Up to 12 company paid holidays + 3 paid days off for Personal Significance 
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit 
  • 401(k) program participation with company matched contributions
  • Employee stock purchase plan 
  • Tuition reimbursement of up to $10,000 per calendar year 
  • Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired.  Read on to learn more about Biogen.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

 

 

Vacancy posted 12 hours ago
Similar jobs that could be interesting for youBased on the Head Rare Diseases, US Medical Affairs (Cambridge, MA) in Cambridge, MA vacancy
  • $320k - $430k

    Vice President, Head of US Medical Affairs, Rare Disease Company: Ipsen Biopharmaceuticals Inc. About Ipsen: Ipsen is a mid‑sized global biopharmaceutical company with a focus on transformative medicines in three therapeutic areas: Oncology, Rare Disease and Neuroscience... 
    Medical
    Temporary work
    Flexible hours

    Ipsen Biopharmaceuticals Inc.

    Cambridge, MA
    4 days ago
  • Sanofi is seeking the US Medical Head for Rare Blood Disorders in Cambridge, MA. You will lead the US RBD Medical Affairs team, shape medical plans, and collaborate with Global Medical, R&D, Safety, and Regulatory to support the portfolio spanning hemophilia and rare hematology... 
    Medical

    Sanofi

    Cambridge, MA
    6 days ago
  • $260k - $367k

     ...About This Role: As the Head of Commercial Field...  ...enablement, and supporting Medical field teams. You will...  ...Neurology, Specialty, Rare Disease, and newly emerging...  ...adjustments. Represent US BIO perspective in leadership...  ...Experience in Medical Affairs planning and tactical... 
    Medical
    Full time
    Temporary work
    Local area

    Biogen

    Cambridge, MA
    12 hours ago
  • Sanofi in Cambridge, MA seeks a US Medical Head for Rare Blood Disorders to lead medical strategies across a broad portfolio including hemophilia. You will...  ...an advanced scientific degree and extensive Medical Affairs leadership experience, #J-18808-Ljbffr BioSpace
    Medical

    BioSpace

    Cambridge, MA
    5 days ago
  • $232.5k - $335.83k

    Job Title: Head of US Public Affairs & Patient Advocacy, ImmunologyLocation: Cambridge, MA / Washington, DC / Morristown,...  ...the gap between when disease begins and when patients...  ...immune challenges, rare diseases, cancers, and...  ...Market Access, PSS, Medical Affairs, HEVA, and R&... 
    Medical
    Full time
    Shift work

    Sanofi

    Cambridge, MA
    5 days ago
  • Ipsen is seeking a Vice President, Head of US Medical Affairs, Rare Disease, to define and lead the US medical vision and strategy across its rare disease portfolio, including liver, bone and kidney initiatives. The role partners with Global Medical Affairs, R&D, Regulatory... 
    Medical

    Ipsen

    Cambridge, MA
    6 days ago
  • Ipsen Biopharmaceuticals Inc. is seeking a Vice President, Head of US Medical Affairs, Rare Disease to set the U.S. medical vision and strategy for a growing rare disease portfolio. The role involves leadership across liver disease, bone/ transplant priorities, evidence... 
    Medical

    Ipsen Biopharmaceuticals Inc.

    Cambridge, MA
    3 days ago
  • $231.99k - $347.98k

     ...Position : Senior Director, Head of Rare Neurology Thought Leader...  ...Liaisons Location : Boston, MA (US Headquarters for Alexion)...  ...of people living with rare diseases. We lead with breakthrough science...  ...field commercial teams, medical affairs, marketing, and senior leadership... 
    Medical
    Temporary work
    Local area
    Night shift
    3 days per week
    Boston, MA
    3 days ago
  • $162k - $223k

    Location: Cambridge, Massachusetts, United StatesSalary...  ...Associate Director, Medical Strategy &...  ...America (NA) Medical Affairs and a core member of Rare Disease LT. The role drives...  ...partners closely with the Head of Rare Disease and...  ...and perspectives make us a stronger and more... 
    Medical
    Temporary work
    Local area

    Biogen Idec

    Cambridge, MA
    1 day ago
  • $183k - $252k

     ...directly. About this role The Nephrology Associate Medical Director role is a part of US Medical Affairs, a strategic partner within Biogen, that helps...  ...mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared... 
    Medical
    Full time
    Temporary work
    Local area

    Biogen

    Cambridge, MA
    12 hours ago
  • $204k - $281k

     ...Role The Director of Rare Disease Market Access Strategy will...  ...and execution of MA&R strategy for Friedreich...  ...role will report to the Head of Rare Disease Access Strategy within the US Market Access & Reimbursement...  ...Partner with Medical, HEOR, Global V&A to support... 
    Medical
    Full time
    Temporary work
    Local area

    Biogen

    Cambridge, MA
    12 hours ago
  • $389.59k

     ...and life-threatening diseases. Beyond our science,...  ...patients are counting on us to make the promise a...  ...Achieve More:The Head of Medical Affairs, reporting to the EVP...  ...therapy, gene editing, rare diseases, or...  ...click here.SummaryLocation: Cambridge, MAType: Full time
    Medical
    Full time
    Local area
    Shift work

    Intellia Therapeutics

    Cambridge, MA
    1 day ago
  • $267k - $377k

     ...Executive Director, Neuromuscular Disease (NMD) Marketing is responsible...  ...close partnership across Medical, Market Access, Patient Services...  ..., and work products. You have US commercial expertise and bring...  ...industry ~ Experience in rare disease preferred ~ Strong analytical... 
    Medical
    Full time
    Temporary work
    Local area

    Biogen

    Cambridge, MA
    12 hours ago
  • $234k - $322k

     ...The Senior Director, Marketing, Rare Disease - Friedreich Ataxia (FA) will be...  ...execution of the FA business within the US. This individual will serve as the US Head and Brand Lead for Friedreich...  ...Patient Services, Market Access, Medical, Advocacy, Market Research,... 
    Medical
    Full time
    Temporary work
    Local area

    Biogen

    Cambridge, MA
    12 hours ago
  • $308.7k - $374.08k

     ...Physician (Cardiovascular)Cambridge Crossing - MA - USFind out how well...  ...job**Working with Us** Challenging....  ...Serves as a clinical/medical contact in diligence-...  ...Commercial, Medical Affairs, and Clinical Pharmacology...  ...management, coronary artery disease, stroke, and heart... 
    Medical
    Hourly pay
    Full time
    Temporary work
    Part time
    For contractors
    Summer work
    Live in
    Work at office
    Local area
    Remote work
    Flexible hours
    Shift work

    Bristol-Myers Squibb

    Cambridge, MA
    6 days ago
  • $27 - $60 per hour

     ...op Opportunities, Cambridge, MA Ready to grow your...  ...- enables us to invent medicines...  ...most challenging diseases affecting the brain...  ...from Alzheimer's to rare neurological disorders...  ...therapies Public Affairs & Patient Advocacy...  ...and safety Medical Affairs: Serve as... 
    Medical
    Hourly pay
    Temporary work
    Apprenticeship
    Summer work
    Internship
    H1b
    Work at office
    Relocation
    Monday to Friday
    Flexible hours

    Sanofi

    Cambridge, MA
    2 days ago
  • $225k - $310k

     ...directly. About This Role The Medical Director, Neuropsychiatry role is a part of US Medical, a strategic partner...  ...reporting to the USM Neuropsychiatry Head , the Medical Director - Neuropsychiatry...  .... Present data at US Medical affairs events, including advisory boards... 
    Medical
    Full time
    Temporary work
    Work at office
    Local area

    Biogen

    Cambridge, MA
    12 hours ago
  • $97.49k - $118.13k

    Working with Us Challenging. Meaningful. Life-changing. Those...  ...solid cancers, and autoimmune disease. More specifically, our...  ...Onsite Compensation Overview Cambridge - MA - US: $97,490 - $118,131 The...  ...benefits include: Health Coverage: Medical, pharmacy, dental, and vision... 
    Medical
    Hourly pay
    Full time
    Temporary work
    Part time
    For contractors
    Summer work
    Live in
    Work at office
    Local area
    Remote work
    Flexible hours
    Shift work

    Bristol-Myers Squibb

    Cambridge, MA
    3 days ago
  • $128.38k - $155.57k

    Working with Us Challenging. Meaningful. Life-changing. Those...  ...solid cancers, and autoimmune disease. More specifically, our...  ...Onsite Compensation Overview Cambridge - MA - US: $128,380 - $155,571 The...  ...benefits include: Health Coverage: Medical, pharmacy, dental, and vision... 
    Medical
    Hourly pay
    Full time
    Contract work
    Temporary work
    Part time
    For contractors
    Summer work
    Live in
    Work at office
    Local area
    Remote work
    Flexible hours
    Shift work

    Bristol-Myers Squibb

    Cambridge, MA
    3 days ago
  • $2,567 per week

     ...Nurse (RN) | Neuro ICU Location: Cambridge, MA Agency: Magnet Medical Pay: $2,567 per week Shift...  ...to chemicals, radiation, infectious diseases/waste and/or blood borne pathogens...  ...create Magnet Medical which allows us to offer more opportunities to our travelers... 
    Medical
    Full time
    Contract work
    Work experience placement
    Flexible hours
    Shift work
    Night shift

    TravelNurseSource

    Cambridge, MA
    1 day ago
  • $360k - $420k

    Vice President, Head of Life Cycle Management Reporting...  ...to the Head of Medical Affairs, the VP, Head of Life Cycle...  ...across our programs and disease areas of interest. The...  ...position is based in Waltham, MA. Responsibilities...  ...website: About Us Alkermes applies its deep... 
    Medical

    Alkermes

    Boston, MA
    6 days ago
  • $148k - $236.5k

     ...Director, Clinical Operations Cambridge, MA USA What if... We could...  ...approaches to serious diseases with unmet medical need. Unique to Pioneering...  ...data management, regulatory affairs, and quality. Lead or contribute...  ...obesity, oncology and/or rare diseases highly desirable.... 
    Medical
    For contractors

    Flagship Pioneering

    Cambridge, MA
    4 days ago
  • $228.2k - $358.6k

    Medical Director, Clinical Science, GI2 TAU- Hematology/Rare Disease Are you looking for a patient-focused, innovation-driven company...  ...empower you to shine? Join us as a Medical Director,...  ...Hematology/Rare Disease in our Cambridge, MA office. At Takeda, we are transforming... 
    Medical
    Minimum wage
    Temporary work
    Work at office
    Local area
    Remote work

    BioSpace

    Cambridge, MA
    6 days ago
  • $190.5k - $265k

     ...research ongoing in additional rare cholestatic liver diseases. WHAT - Main...  ...and operational budget for US market Own and drive the adult...  ...simultaneously Strong scientific/medical aptitude and experience...  ...week, on average, from our Cambridge, MA HQ Ability to travel to... 
    Medical
    Temporary work
    Flexible hours
    Night shift
    3 days per week

    Ipsen

    Cambridge, MA
    4 days ago
  • $206.25k - $343.75k

    Job title: US Senior Medical Director, Rare HematologyLocation: Cambridge, MA / Morristown, NJAbout the jobJoin...  ...immune challenges, rare diseases, cancers, and...  ...member of the US Medical Affairs team within the Rare Blood...  ...portfolio and reports to the Head of US Medical Affairs,... 
    Medical
    Full time

    Sanofi

    Cambridge, MA
    2 days ago
  • $278k - $382k

     ...recruiter directly. Senior Medical Director, Global Medical Affairs, CD38 Pipeline Immunology...  .... Reporting to the Head of Global Medical Nephrology...  ...for other immune mediated diseases driven by pathogenic antibody...  ...cultures, and perspectives make us a stronger and more... 
    Medical
    Full time
    Temporary work
    Local area

    Biogen

    Cambridge, MA
    12 hours ago
  • $299k - $332k

    Senior Medical Director, Oncology Clinical Development (Office Based - Cambridge, MA) Full-time Zai Lab is a patient-focused...  ..., and infectious disease. Guided by innovation...  ...with regulatory affairs, clinical operations,...  ...Job Location #J-18808-Ljbffr Zai Lab (US) LLC
    Medical
    Full time
    Work at office
    Worldwide
    Relocation package

    Zai Lab (US) LLC

    Cambridge, MA
    6 days ago
  • Ipsen Biopharmaceuticals Inc. in Cambridge, MA seeks a Director of Key Opinion Leader Marketing for Rare Disease to lead external expert engagement and peer-to-peer education...  ..., and congress strategy, partnering with Medical, Regulatory, Legal, and Ethics to ensure compliant... 
    Medical

    Ipsen Biopharmaceuticals Inc.

    Cambridge, MA
    6 days ago
  • $225k - $310k

     .... About This Role The Medical Director, Global Medical Affairs, Nephrology will be a strategic...  ...to the Global Medical Head of Nephrology, the Medical...  ...of the Nephrology Disease area. You also have significant...  ...Strong working knowledge of US and ex-US regulations as relevant... 
    Medical
    Full time
    Temporary work
    Local area

    Biogen

    Cambridge, MA
    12 hours ago
  • $194k - $267k

     ...directly. About This Role The Rare Neurology Development Unit (RNDU...  ...Ataxia (FA) or Huntington's disease. As a member of the RMD and FA team, the Associate Medical Director will support early and/...  ...cultures, and perspectives make us a stronger and more innovative company... 
    Medical
    Full time
    Temporary work
    Local area

    Biogen

    Cambridge, MA
    12 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Head Rare Diseases, US Medical Affairs (Cambridge, MA). Be the first to apply!