Senior Scientist

Location: Redwood City Company Overview ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life‑threatening diseases. With a highly experienced team of experts in immunology and drug development, we are pioneering innovative approaches to target and modulate key molecular pathways that regulate the immune response. At ImmunEdge, we are driven by a shared commitment to improving human health through innovative science. We are building a culture based on kindness, collaboration, and a deep passion for advancing science. As an early joiner to the company, you will help cultivate an environment where every team member is encouraged to challenge ideas, think critically, and contribute their unique perspectives. We value openness, transparency, and continuous learning, and want to empower our employees to take ownership of their work while fostering a sense of community and teamwork. Whether you’re working in the lab, the office, or across functional teams, you will find an inclusive space where your contributions matter and your professional growth is supported. Join us in shaping the future of biotechnology. Together, we can change lives. Position ImmunEdge has an exciting opportunity for a Senior Scientist with strong in vivo pharmacology, flow cytometry, and cancer immunology experience to join our In Vivo Pharmacology team. This individual will play a key role in advancing preclinical oncology and immunology programs by designing, executing, and analyzing in vivo studies and mechanistic ex vivo assays to support target validation, candidate selection, and translational strategy. Strong candidates will be highly collaborative, scientifically rigorous, and passionate about drug discovery and immune‑mediated diseases. Experience working in a dynamic, early‑stage biotech environment and contributing across discovery workflows is highly valued. Key Responsibilities Design, execute, and interpret in vivo efficacy, PK/PD, and mechanistic studies in relevant oncology and immunology models. Develop and optimize ex vivo assays, including MSD, ELISA, RNAseq, and functional readouts to support target biology and mechanism of action. Perform and analyze multi‑parameter flow cytometry experiments, including panel design, staining optimization, acquisition, and advanced data analysis to characterize immune and tumor cell populations. Collaborate with discovery, translational, and biomarker teams to integrate in vivo and ex vivo data and guide program strategy. Analyze complex datasets and communicate findings clearly to cross‑functional stakeholders with diverse scientific backgrounds. Contribute to study planning, experimental timelines, and data‑driven decision making for program advancement. Maintain accurate, well‑organized experimental records while ensuring a safe, compliant, and reproducible lab environment. Identify opportunities to improve in vivo and ex vivo assay platforms and evaluate emerging technologies relevant to ImmunEdge’s pipeline. Qualifications Ph.D. in Immunology, Pharmacology, Oncology, Molecular and Cellular Biology, or a related field; or M.S. with additional relevant industry experience. 5+ years of industry experience in drug discovery or development, with significant hands‑on experience in in vivo models. Strong technical expertise in in vivo pharmacology and disease models (oncology and/or immunology preferred). Flow cytometry (panel design, immune phenotyping, functional assays, data analysis). MSD, ELISA, and ex vivo functional assays. Experience integrating in vivo and ex vivo data to support mechanism of action and translational hypotheses. Proficiency with standard laboratory techniques such as ELISA, qPCR, western blotting, and cytokine assays. Ability to independently plan and execute experiments, troubleshoot complex problems, and rigorously interpret scientific data. Strong collaboration, communication, technical writing, and organizational skills. Ability to thrive in a fast‑paced, supportive start‑up environment. Preferred Qualifications (Plus) Experience with PK/PD or bioanalytical assays. Experience writing technical reports for IND‑enabling studies. Familiarity with immuno‑oncology targets or immune‑modulating therapeutics. Prior CRO management or cross‑functional project experience. Expected Salary Range: $154,000 - $170,000 We encourage candidates of all levels to apply as there is sometimes flexibility on job level and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications, internal equity, and location. ImmunEdge offers a competitive employment package that includes an annual bonus plan, equity, and a generous benefits package including comprehensive health (medical, dental, and vision) insurance for our employees and their families, a 401(k) plan, FSA plans (medical, dependent), an Employee Assistance Plan, and a holiday and paid time off plan. At ImmunEdge, we believe that a diverse, open, and inclusive environment and culture is key to our success. We will not be influenced in recruiting, hiring, promoting or any other employment practices by race, color, citizenship status, national origin, ancestry, sex, sexual orientation, gender identity/expression, age, religion, physical or mental disability, medical or genetic condition, marital status, veteran status, or any other characteristics protected under applicable federal, state and local laws. ImmunEdge will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable laws. Note to External Recruiters: Submission of unsolicited resumes prior to an agreement in place does not create any implied obligation. #J-18808-Ljbffr ImmunEdge, Inc