Sr Clinical Research Associate

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Sr Clinical Research Associate based in United States. This role offers an opportunity to play a critical part in the successful execution of clinical trials and observational studies. You will monitor study sites, support protocol compliance, and help safeguard the quality and integrity of clinical data. The position combines independent site management with close collaboration across project and clinical teams. You will work directly with research sites, investigators, and study stakeholders in a regulated environment. As a senior team member, you will also mentor and support junior Clinical Research Associates, contributing to their development and performance. With substantial travel across North America, this is a dynamic role for an experienced clinical research professional who values accuracy, collaboration, and meaningful impact on healthcare. Accountabilities: Conduct remote and on-site monitoring activities in accordance with study protocols, project-specific monitoring plans, timelines, applicable regulations, and sponsor requirements. Apply thorough knowledge of assigned protocols and ensure clinical research sites maintain compliance throughout study execution. Manage site activities including selection, initiation, ongoing management, monitoring, issue follow-up, and closeout-related activities as applicable. Maintain regular communication with assigned sites and ensure timely resolution of site issues, action items, and study-related questions. Complete accurate site monitoring reports, follow-up letters, visit documentation, and other required records in accordance with applicable SOPs. Maintain accurate study information in the Clinical Trial Management System (CTMS), including site visits, monitoring reports, contact information, and follow-up activities. Monitor data entry within Electronic Data Capture (EDC) systems when applicable and support sites with electronic Case Report Form (eCRF) queries and resolution. Review Investigator Site Files and perform Investigational Product reconciliation as required by study procedures. Support project teams with study-related activities, attend project and departmental meetings, and communicate progress, risks, and outstanding actions effectively. Mentor, train, and assess junior Clinical Research Associates, helping strengthen monitoring practices and professional capabilities. Assist with the preparation and delivery of CRA, departmental, and sponsor-specific training and presentations. Maintain compliance with required SOP training, assessments, and documentation within established timelines. Manage travel arrangements and expense reporting in accordance with applicable policies and project requirements. Collaborate with Project Managers, Lead CRAs, management, and other departments to support successful study delivery and take on additional project responsibilities as needed. Travel extensively across the North American region, with travel expected to be up to 80%. Requirements: Bachelor’s degree in Life Sciences or a related discipline preferred, or an equivalent combination of industry experience and clinical research experience. At least 36 months of on-site clinical monitoring experience, including site selection, site initiation, site management, and monitoring activities. Strong knowledge of medical terminology, clinical research processes, applicable regulatory requirements, and clinical trial guidelines. Experience working with clinical trials and/or observational studies is preferred. Familiarity with clinical research technology, including CTMS, eTMF, EDC, and Microsoft Office applications. Strong critical-thinking, problem-solving, and issue-resolution skills, with the ability to identify risks and determine appropriate corrective actions. Excellent written and verbal communication skills in English and, where applicable, the relevant local language. Proven ability to produce highly accurate documentation and deliver quality work while meeting strict deadlines. Strong organizational skills and the ability to manage multiple site activities and priorities in a fast-paced, regulated environment. Ability to work collaboratively with project teams, study sites, investigators, and other stakeholders while also operating independently. Demonstrated professionalism, attention to detail, accountability, and commitment to data quality and participant safety. Willingness and ability to travel extensively, including up to 80% travel throughout North America. Benefits: Remote work opportunities. Competitive salary. Opportunities for career growth and internal promotion. 401(k) retirement plan with company match. Tuition reimbursement. Flexible work environment. Discretionary paid time off (PTO). Paid holidays. Employee assistance programs. Medical, dental, and vision insurance. Health Savings Account (HSA) and Flexible Spending Account (FSA) options. Telemedicine and virtual healthcare appointments. Employee wellness programs. Adoption assistance. Short-term and long-term disability coverage. Life insurance. Employee discount programs. Inclusive workplace committed to diversity, equity, and respect. #J-18808-Ljbffr Jobgether