Bioinformatics Engineer, Variant

As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analysis, empowering over 5,000 scientists across 150+ R&D labs to handle data from instrument-to-insights. We're seeking a BioEngineer for Genomics to join our genomics bench, working at the frontier of what artificial intelligence can achieve in biology. About the Role You will contribute to our technical approach to teaching agents how to understand and handle complex genomic data, working across end-to-end data analysis workflows from instrument outputs to real scientific decisions. You will work as part of a team of software engineers and biologists building datasets to teach these agents to reason better across: Sequencing QC → alignment & assembly Variant calling & filtering Clinical variant interpretation Population genetics → algorithmic reasoning Requirements 5+ years hands-on experience with genomics or genetics data Experience in drug mechanism of action studies using population genomics Proficiency in Python and/or R Compensation & Logistics OTE 120k - 180k, performance based, based on individual's expertise Free meals (lunch and dinner) Waterfront office in China Basin, San Francisco Full-time, in-person (can be remote) LatchBio