Global Clinical Trial Manager Equity, PTO & Impact

Structure Therapeutics develops life‑changing medicines for patients using advanced structure‑based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‑stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions. Position Summary Structure Therapeutics is seeking a highly motivated Sr. Clinical Trial Manager (SCTM) to be part of our Clinical Operations team. The SCTM will oversee day‑to‑day global clinical trials, manage internal stakeholders, CROs, multiple service providers, clinical monitors, and trial sites. The role focuses on multinational, multicenter Phase II studies and may expand to additional studies or indications as needed. Job Responsibilities Lead and coordinate global cross‑functional study teams through all study stages (start‑up, conduct, close‑out). Drive the RFP and RFI process, analyze service provider proposals, conduct bid defense meetings, negotiate, and execute complex agreements. Provide oversight and direction to CROs and service providers to ensure accurate coordination of study activities. Assist with inspection readiness activities, modifying or implementing policies as needed. Coordinate clinical study timelines with project management and raise issues that could impact timelines or deliverables. Lead or participate in the development and review of study documents—CRF design, project plans, service provider oversight plans, TMF plan. Follow processes and recommend changes to SOPs and policies to maintain compliance. Identify potential study issues or risks, raise them, and recommend or implement solutions. Manage study sites and related activities, including feasibility, selection, start‑up, recruitment, enrollment, monitoring report review, and data clean‑up. Coordinate with finance to track the financial status against budget. Provide regular updates to the study lead and stakeholders; proactively manage or raise issues. Prepare or review clinical sections of regulatory submission documents and respond to ethics committee or health authority inquiries. Monitor study progress for possible scope changes and manage change orders, training implementations, and monitoring. Oversee the study budget, including site and service provider budgets. Supervise ongoing operational communication and provide accurate progress reports to the study management team. Ensure data and information in study‑specific systems (EDC, CTMS, eTMF) is current and accurate. Lead or contribute as a subject‑matter expert to key projects, implementing process improvements and standards. Other supportive duties as assigned to ensure operational excellence. Education Bachelor’s degree or equivalent (scientific or healthcare discipline preferred) Experience Minimum of 7+ years of related industry experience as a Clinical Research Associate or related function with increasing responsibility and scope. Minimum of 3+ years of study management experience in clinical and drug development. Experience selecting, managing, and overseeing sites, CROs, specialty labs, and other service providers in global, multinational studies. Experience supporting SOP development and implementation. Desired experience working on global teams, especially in Asia‑Pacific and EU. Core Competencies PC literacy required; MS Office skills (Outlook, Word, Excel, PowerPoint). In‑depth understanding of FDA and EU regulations, ICH Guidelines, and GCP requirements governing clinical trials. Travel required: Up to 30%. Structure Therapeutics Inc. is an Equal‑Opportunity Employer. Structure Therapeutics is committed to fair and equitable compensation practices and offers a competitive total compensation package, including base pay in the range of $171,000‑$223,000, performance incentive bonuses, equity, medical, dental, and vision insurance, 401(k) match, unlimited PTO, and paid holidays including winter shutdown. #J-18808-Ljbffr