Director Clinical Pharmacology & DMPK
$200k - $240kAlumis
Director Clinical Pharmacology & DMPK
South San Francisco
Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
Alumis is seeking a Director of Clinical Pharmacology & DMPK to drive clinical pharmacology strategy and PK/PD modeling for our small-molecule programs in immune-mediated diseases. This role partners closely with cross-functional teams and reports to the Head of Clinical Pharmacology & DMPK.
Specific responsibilities include but are not limited to:
- Lead clinical pharmacology strategy, dose selection, and PK/PD and biomarker planning across early and late-stage programs.
- Conduct and interpret PK, PK/PD, exposureresponse, and simulation analyses using tools such as NONMEM, WinNonlin, R, Python, and Simcyp.
- Integrate translational and nonclinical PK/PD data to support FIH dose projections and DDI assessments.
- Oversee bioanalytical CROs, ensuring high-quality PK/PD/biomarker data and GLP/GCP compliance.
- Partner with Clinical Operations on sample management and protocol design.
- Communicate quantitative findings clearly and contribute to regulatory documents (protocols, IBs, INDs, NDAs, IMPDs).
- Collaborate across Clinical Development, Biostats/Data Science, Nonclinical, and Program Management.
Key requirements and qualifications:
- PhD, PharmD, or equivalent in Pharmacokinetics, Pharmacology, or related field.
- 6 to 8+ years of industry experience in Clinical Pharmacology, DMPK, or Quantitative Pharmacology.
- Strong expertise in PK, PK/PD, DMPK, and translational sciences.
- Proficiency with modeling/simulation platforms (NONMEM, WinNonlin, Simcyp, R, Python).
- Excellent communication, organization, and ability to work independently in a fast-paced environment.
Alumis Inc. is an equal opportunity employer.
The salary range for this position is $200,000 USD to $240,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company's compensation practices.
This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.
Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
Other benefits include:
- Health insurance premiums paid at 90% for employee, 80% for dependents
- Free access to Genentech Bus Share program
- $100 monthly cell phone stipend
- Unlimited PTO for Exempt employees
- Free onsite gym and a kitchen stocked with yummy snacks and drinks!
We are a hard-working, collaborative team on a mission to transform patient's lives-- and we aspire to elevate, challenge and nurture one another along the way.
AlumisVacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Director Clinical Pharmacology & DMPK in South San Francisco, CA vacancy
$235.5k - $329.5k
...Senior Director, Clinical Pharmacology and Translational PK/PD Vir Biotechnology is looking for an experienced Sr. Director of Clinical Pharmacology... ...13+ years industry experience in Clinical Pharmacology, DMPK and/or related fields Mastery of nonclinical and...SuggestedFull timeWork at officeWork visa3 days per week$270k - $360k
...Medical Director/Senior Medical Director, Clinical Development TenvieTherapeutics is developing precision‑engineered small molecule therapies to... ...interactions Partner with Biostatistics, Clinical Pharmacology, and Translational Science on endpoint hierarchy, statistical...SuggestedLocal areaRemote workTenvie Therapeutics
South San Francisco, CA4 hours ago$144k - $240k
...mediated diseases by developing novel targeted therapies with outsized clinical impact, faster. To accomplish this, we are seeking top talent to join us on our journey.As the Lead, Clinical Pharmacology, Immunology, you will serve on program and study teams, providing...SuggestedTemporary workLocal area- Atara Biotherapeutics: Director, Clinical Research and Development (Immuno-Oncology - Hematology/Oncology) Director, Clinical Research and... ...clinical trials to evaluate the efficacy, safety, clinical pharmacology, and pharmacokinetics of biologic and cellular...Suggested
$300k - $400k
...Senior/Executive Medical Director, Clinical Development (New Indications) Alumis Inc. is a precision medicines company with the mission... ...Work closely with Translational Sciences, Biomarker, and Pharmacology teams to integrate biomarker strategies into clinical study...SuggestedRemote work- .... Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube. Job Description Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning...Full timeTemporary workLocal area
- Medical directors of Oncology Clinical Research - San Francisco Tanner and Associates is recruiting several Medical directors of Oncology Clinical... ..., biostatistics, clinical operations, regulatory and pharmacology for input/alignment and presentation at the Therapeutic...Interim role
- Associate Director Clinical Pharmacology - San Francisco Biotech New Position: Associate Director Clinical Pharmacology - San Francisco Biotech Position Summary: The Associate Director role will have a broad range of responsibilities and oversight of programs in oncology...
- A leading biotechnology company in San Francisco is seeking an Associate Director of Clinical Pharmacology. The ideal candidate will oversee clinical pharmacology programs in oncology and other areas, requiring both strategic and hands-on experience. Responsibilities include...
$235.5k - $329.5k
...Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering... ...best. THE OPPORTUNITY The Senior Director, Clinical Research Oncology will... ...integration of clinical, translational, pharmacology, biometrics, and regulatory perspectives...Full timeWork at officeWork visa$280k - $315k
...Medical Director The position of Medical Director will be an essential part of the clinical development team and will report to the Chief Medical Officer. The Medical... ...Familiarity with the general principles of pharmacology/toxicology as it relates to first-in-human...Work at officeRelocation$261k - $325k
...limitations of biologic and peptide drugs. We are advancing a clinical‑stage pipeline of differentiated treatments focused on chronic... ...geographic location. Position Summary We are seeking a Senior Director, Clinical Operations, who acts as both a strategic leader and a...Contract workWork at officeStructure Therapeutics Inc.
South San Francisco, CA4 days ago$190k - $280k
...extracellular protein degraders to the clinic. Lycia is headquartered in South San Francisco... ...Lycia Therapeutics is seeking a Director or Associate Director of Clinical Science... ...data to evaluate safety, efficacy, and pharmacological properties of investigational products....Work at officeFlexible hours2 days per week3 days per weekLycia Therapeutics
South San Francisco, CA3 days ago- Structure Therapeutics Inc. in South San Francisco is seeking a Senior Director, Clinical Operations to oversee global clinical trial delivery. This role requires strong leadership in clinical operations, ensuring compliance and effective team management. The ideal candidate...3 days per week
$230k - $270k
Allogene Therapeutics is seeking a Senior Director to lead the Portfolio & Program Management Team in South San Francisco. This role involves managing a cross-functional team to drive execution of key programs in the biotech space. Required qualifications include a Bachelor...$211k - $258.67k
Overview Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and...Temporary workWork experience placementLocal area$230k - $270k
...Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of... ...About the role We are looking for a talented, motivated Senior Director to join our Portfolio & Program Management Team as a key leader...Local areaRemote work$247k - $340k
About This Role:As the Head of Clinical Pharmacology & Pharmacometrics for the West Coast Hub (WCH), you will spearhead the strategic oversight and integration of Clinical Pharmacology and Pharmacometrics across our development portfolio. This pivotal role provides senior...Temporary workLocal area$161k - $222k
## Associate Director, Clinical Biomarkers LeadApplyremote type: Hybridlocations: San Francisco, CAtime type: Full timeposted on: Posted... ...translational immunology, clinical research, biometrics, clinical pharmacology, and others to execute translational studies and analyze...Contract workTemporary workLocal area- Associate Director, Clinical Biomarkers Lead Responsibilities Develop and implement comprehensive biomarker strategies for therapeutic programs... ...immunology, clinical research, biometrics, and clinical pharmacology to execute translational studies and interpret biomarker...Temporary work
$360k - $420k
...Lycia Therapeutics is seeking a Clinical Development Leader to advance their drug pipeline in South San Francisco. This role involves overseeing mid- and late-phase clinical trials, ensuring regulatory compliance, and collaborating with various teams. Ideal candidates...Lycia Therapeutics
South San Francisco, CA3 days ago$245k - $318k
...patients. Key Accountabilities/Core Job Responsibilities Provide strategic leadership and development for Data Management (DM) and Clinical Programming (CP) teams across the full data lifecycle Oversee end-to-end DM and CP deliverables from study start-up through...Local area- A leading biotechnology company in South San Francisco seeks a Director of Clinical Regulatory to oversee multiple clinical drug candidates and drive development as a regulatory project lead. The role involves overseeing global Health Authority interactions, leading project...
$200k - $210k
Summary The Associate Director, Clinical Science will be a key contributor to the scientific, clinical, and operational scope of clinical development programs in both inflammation/immunology and oncology, with an emphasis on program-specific activities. The Associate Director...Work at officeRemote workFlexible hours$240k - $300k
...Medical Director, Clinical Development - Oncology Using living cells to treat and sometimes even cure cancer is one of the most dramatic advances in modern medicine. Patients with hematologic malignancies have been successfully treated with cell therapies. However,...Local area- A biopharmaceutical company is seeking a Director of Clinical Research and Development to design and manage clinical trials in immuno-oncology and hematology-oncology. The ideal candidate will have a strong background in clinical drug development, an M.D. or M.D., Ph.D...
$270k - $294.5k
...Senior Director, Clinical Research (Medical Director) Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases...Summer holiday3 days per week$195.67k - $253.22k
...Associate Director, Clinical Pharmacology At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer working relentlessly to develop therapies that help improve lives and...Work at officeFlexible hours- Position Summary Seeking an Corporate and Clinical Contracts consultant, who will be an integral member of the Legal Department, and will be accountable for legal and risk tolerances, contracting standards, and process and strategy in support of Structure’s strategic objectives...Contract work
$234k
...Leads the direction, planning, execution, and interpretation of clinical trials or research activities of one or more clinical... ...documents. May oversee the work of Medical and/or Scientific Directors and of Clinical Scientists working on the same or related programs...Work at officeImmediate startRemote workMonday to Friday
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Director Clinical Pharmacology & DMPK. Be the first to apply!
Related searches
- health insurance manager South San Francisco, CA
- director sr. director clinical operations South San Francisco, CA
- clinical data manager South San Francisco, CA
- medical director neurology South San Francisco, CA
- senior director clinical operations South San Francisco, CA
- healthcare consulting manager South San Francisco, CA
- health services director South San Francisco, CA
- senior medical director medical affairs South San Francisco, CA
- associate director clinical data management South San Francisco, CA
- remote medical billing manager South San Francisco, CA