Medical Director

JOB TITLE: Medical Director, Oncology

REPORTS TO: Senior Vice President, Head of Clinical Development

DATE PREPARED: March 12,2026

JOB SUMMARY:

AVEO Oncology is seeking a highly skilled and experienced Medical Director to join our dynamic team. The successful candidate will have a strong background in oncology, specifically renal cancer, previous experience in early phase development strongly preferred; and a proven track record in managing global clinical trials. This role is pivotal in driving the clinical development of our oncology pipeline and ensuring the successful execution of our clinical programs.

PRINCIPAL DUTIES:

1. Leadership skills:

* Provide medical and scientific leadership in the design, execution, and interpretation of Phase I clinical studies.

* Collaborate with cross-functional teams, including clinical operations, regulatory affairs, and biostatistics, to ensure alignment on clinical strategy and study design.

* Ensure clinical trials are conducted in compliance with applicable regulations, guidelines, and company policies.

* Oversee clinical aspects of global clinical studies, ensuring consistency and quality across all regions.

* Lead interactions with key opinion leaders to align clinical development plans.

2. Medical Monitoring and Safety Oversight:

* Serve as the medical monitor for assigned clinical trials, providing ongoing medical oversight and guidance, addressing any issues that arise to ensure timely completion and high-quality data.

* Assess and interpret clinical trial data, ensuring accuracy and completeness of safety and efficacy information.

* Collaborate with pharmacovigilance teams to monitor and manage adverse events and other safety concerns.

3. Data Analysis and Reporting:

* Participate in data analysis, interpretation, and presentation of clinical study results to internal and external stakeholders.

* Contribute to the preparation of clinical study reports, regulatory submissions, and scientific publications.

* Present clinical data at scientific conferences and advisory boards.

4. Stakeholder Engagement:

* Develop and maintain strong relationships with key opinion leaders, investigators, and clinical trial sites.

* Represent AVEO Oncology at scientific meetings, conferences, and industry events.

REQUIRED QUALIFICATIONS/EXPERIENCE (BASIC QUALIFICATIONS):

Education:

* Medical Doctor (MD) degree is required.

Experience:

• Minimum of 3-5 years of experience in oncology clinical development, familiarity with Phase I and phase II clinical studies is required.

* Demonstrated experience in managing global clinical trials and navigating international regulatory environments.

Skills:

* Strong clinical and scientific acumen in oncology.

* Excellent leadership, communication, and interpersonal skills.

* Proven ability to work effectively in a cross-functional, global team environment.

* Strong analytical and problem-solving skills with keen attention to detail.

Preferred Qualifications:

* Experience working within a biotechnology or pharmaceutical company.

* Demonstrated ability to drive clinical development strategies and make data-driven decisions.

* Prior experience interacting with global regulatory agencies and key opinion leaders.

* Experience in renal oncology clinical trials.

About AVEO

AVEO is a commercial-stage, oncology-focused biopharmaceutical company committed to delivering medicines that provide a better life for patients with cancer. AVEO currently markets FOTIVDA (tivozanib) in the U.S. for the treatment of adult patients with relapsed or refractory renal cell carcinoma (RCC) following two or more prior systemic therapies. AVEO continues to develop FOTIVDA in immuno-oncology combinations in RCC and other indications and has several other investigational programs in clinical development. AVEO is committed to creating an environment of diversity, equity and inclusion to diversify representation within the Company.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.