Senior Director, Engineering and Technology (Holly Springs)
$173.95k - $323.05kRoche
Welcome to Holly Springs, North Carolina— home to Roche/Genentech's largest-ever investment: a $2B greenfield start-up where next-generation technology, high-performing teams and Operational Excellence converge to create the global standard for high-volume, highly-efficient Drug Product manufacturing. The facility's core is defined by Innovation - leveraging advanced automation, robotics, digital tools, real-time data analytics, and simple, streamlined processes to produce the highest quality medicines. This plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes. This is a fast-paced, entrepreneurial environment with a high-level of accountability, with planned launch in 2028. Are you a problem-solver and change-agent who thrives in a Team environment, eager to tackle the most complex manufacturing challenges? If so, this is a once-in-a-lifetime opportunity to launch a state-of-the-art facility from the ground-up and shape the culture of our organization for the next generation. Join us in Holly Springs, where you won't just build a plant—you will build the future of medicine. The Opportunity: As Head of Engineering you will lead the overall Engineering, Sciences, and Technology strategy at Holly Springs. You will be a part of the equipment, facility and utility selection, qualification and lead the operational start-up of the assets in the new Greenfield build to the ongoing lifecycle management of the plant. You will lead the site Maintenance & Reliability program, Capital execution, Asset lifecycle Management and deploy a world-class Asset Management program, to maintain the utility systems to the highest levels of compliance and manage all site facility services, to enable high-volume parenteral manufacturing. You will enable and empower your team to deliver our vision through a culture of Continuous Improvement and Innovation, developing a highly engaged team and bringing new technology to proactively reduce asset related cost, improve operational availability and efficiently deploy Capital investment. You are overall responsible for capital project engineering management in Holly Springs over the whole asset and facility lifecycle, including business strategic planning and site master planning. You are also responsible for establishing a World-class asset maintenance management system. To bring the highest level of technical expertise and support to Holly Springs, you will develop a network and foster collaboration between global functions, equipment suppliers, local expertise and other Roche manufacturing sites. You will be part of the Site Leadership Team and report to the Site Head. You will bring strong creative leadership skills and proven ability to be a problem solver and innovator, able to lead through change and ambiguity. You will build forward -thinking outlook; remove barriers, develop people and technical capabilities; build an environment which enables people to perform at their best You will lead Roche’s mission of sustainability to enable a fully sustainable plant. You will implement, coach and apply lean and agile ways of working You will develop and communicate organizational strategies, which ensure the GMP compliance of the site, continuous improvements and achievement of long-term goals You will lead, coach, and guide the organization. Manage performance and development of the members of the Engineering Unit to achieve organizational goals and employee personal and professional growth You will build a strong pipeline of talent and robust succession plans for key positions. You will build a culture of continuous improvement and model lean leadership principles Who you are: You actively pursue new ideas and question conventional thought patterns. You appreciate working in a dynamic organization with ambitious goals and an environment characterized by mutual respect, open dialogue and collaboration across numerous global and local interfaces. You have a Bachelor’s Degree (engineering discipline) - Graduate Degree or MBA is preferred. You have 15 or more years work experience in the pharmaceutical industry with at least 6 or more years of people and project management experience and 4 or more years’ facilities management, engineering, or related experience in the pharmaceutical industry You have experience leading Maintenance Strategy and world-class maintenance programs. You have dedication to serve internal and external customers, passion for developing people and shaping a new organization to deliver You have extensive experience in collaboration and project management in cross-functional teams and high interface competence and good leadership skills in a matrix organization You are familiar with manufacturing and business processes at a site; understanding of the opportunities and challenges within the network You possess good assertiveness in a global environment and a continuous approach to improvement You have a proven ability to coach and implement lean ways of working - understands and applies agile ways of working. You have excellent communications skills in English and the ability to effectively communicate and influence across all levels of the organization The expected salary range for this position based on the primary location for this position of Holly Springs is $173,950 - $323,050. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Link to Benefits Relocation benefits are provided Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. Who We Are Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. The next step is yours. To apply today, click on the "Apply for this job" button. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$78.9k - $146.5k
...new large‑volume, low‑cost drug product manufacturing site will be built in Holly Springs, North Carolina. ITOT will own and operate the manufacturing technology stack there. The SrMES Engineer will participate in greenfield project execution and later support operations...SeniorLocal areaWorldwideRelocation$114.7k - $212.9k
Overview Welcome to Holly Springs, North Carolina— home to Roche/Genentech's largest-ever... ...greenfield start-up where next-generation technology, high-performing teams and Operational... ...MSAT, Operations, Warehouse, Engineering, Quality, QC, and Global QMS teams, to...SuggestedContract workLocal areaRelocation package$95.2k - $176.8k
...manufacturing for Roche. A new manufacturing site is being built in Holly Springs, North Carolina, focused on large volume low‑cost drug... ...manufacturing. This role is a Principal Instrumentation & Controls Plant Engineer, the site’s highest-level technical subject matter expert in...SuggestedLocal areaRelocation package$81.4k - $151.2k
...equipment including procedures and training; support FATs for Packaging Equipment; flex to support other Holly Springs assets; partner and collaborate with Engineering, MSAT, Quality, Supply Chain, Technical Development, Regulatory, CMO, and Strategy; transition from...SuggestedFull timeLocal areaRemote workFlexible hoursShift work$81.4k - $151.2k
..., PTM will construct a new manufacturing site in the U.S. in Holly Spring, North Carolina. The new site will focus on large volume low... ...Assembly Equipment; work as part of the User Team; collaborate with Engineering, MSAT, Quality, Supply Chain, Technical Development,...SuggestedLocal areaRemote workFlexible hoursShift work$200k - $250k
...A leading adventure sports technology company is seeking an entrepreneurial-minded engineering leader in San Francisco. This role involves overseeing product design and development for outdoor communication devices. The ideal candidate has over 10 years of experience in...Senior- ...DocuSign, Inc. in San Francisco is seeking an Application Engineering Leader to transform its business technology landscape through software and AI solutions. This hybrid role involves leading engineering teams, driving technology innovation, and ensuring alignment with...Senior
$173.2k - $321.6k
...The Position Senior Product Engineering Manager - Commercial Pharma US Patient 360 Insights Roche Digital Technology (RDT) is where innovation meets purpose. As a global team at the heart of Roche, we are a community of business-minded technologists committed...SeniorLocal areaRelocation package- ...Product Software Leader Join us at Zoox, where cutting-edge technology meets the open road. We are revolutionizing transportation... ...in-vehicle user experience. Drive adoption of best software engineering and infrastructure automation practices to increase efficiency...Senior
- ...A leading technology company in San Francisco is looking for a Senior Engineering Manager to oversee the Model Serving product. This role involves leading a high-performing engineering team, defining the product roadmap, and ensuring the product meets rigorous performance...Senior
$231k - $318k
...About Faire Faire is a technology wholesale platform built on the belief that the future is local. Independent retailers around the... ...discovery experience in wholesale: one that feels less like a search engine and more like a trusted merchant with an encyclopedic knowledge...SeniorWork experience placementWork at officeLocal areaRemote workMonday to FridayFlexible hours3 days per week- ...A tech-driven company in San Francisco seeks a Senior Engineering Manager to lead and scale an engineering team working on an innovative... ...engineering teams and a strong technical background in relevant technologies. This position offers a competitive salary and equity in a...Senior
$300 per month
...energy and intelligence. We’re crafting the engine that powers a world where people can... ...part of the AI revolution with sustainable technology at Crusoe. Here, you'll drive meaningful... ..., transformative cloud infrastructure. Senior Engineering Manager, Compute San...SeniorTemporary work$261k - $326k
...A technology company specializing in AI infrastructure is seeking a Principal Engineer to enhance reliability and scalability of cloud systems. This role demands over 15 years of experience in production engineering or related fields and involves setting technical directions...Senior- ...A technology company in San Francisco is looking for a Senior Engineering Manager, Data Plane Systems to lead high-performance SDN data planes. This hands-on leadership role requires at least 10 years of experience in networking or systems engineering. Responsibilities...Senior
$180.6k - $289.3k
...Senior DevOps Engineering Leader VisaNet, is the Next Generation VisaNet, will push the envelope of building highly scalable, secure, cost... ...distributed application on commodity hardware using best-in-class technology components. Open VisaNet is one of Visas Key initiatives...SeniorWork experience placementWork at officeLocal areaVisa sponsorshipShift work- ...A consumer electronics company in San Francisco seeks an experienced engineering leader to drive product development for outdoor and wearable devices. The ideal candidate has over 10 years of experience in product design and engineering management, particularly in high...Senior
- ...A leading technology firm in San Francisco seeks a Senior Engineering Manager to lead a team focused on high-performance computing for AI. The ideal candidate will have over 5 years of experience in engineering management and a background in systems programming. Responsibilities...Senior
- ...A leading drone technology company is seeking experienced engineering leaders to enhance its autonomy team. The role involves managing product roadmaps and teams while scaling innovations in autonomous flight technology. Candidates should possess strong software engineering...Senior
$200k - $280k
...Director of Engineering Job type: Full Time · Department: Technology · Work type: Hybrid · USD 200,000-280,000 / year Charlotte, North Carolina, United States; San... ...Technical Stack Languages/Frameworks: Java, Kotlin, Spring Boot. Infrastructure: AWS (EKS, S3, SNS, SQS,...Full time- ...Drips.com is seeking a Senior Manager, Device Quality Engineering to advance the quality and compliance of our medical technology products. You will lead a team to ensure our AI-driven cardiac solutions meet high regulatory standards while driving innovations in health...Senior
$180k - $220k
...things move for businesses, governments and consumers. The technology is complex but the idea is simple: a teleportation service that... ...About You and the Role Zipline is hiring a Mechanical Test Engineering Manager that is excited to lead the team responsible for testing...SeniorLocal area$200k - $275k
...drone company and the world leader in autonomous flight, the key technology for the future of drones and aerial mobility. The Skydio team... ...regions and deployment models. We are seeking an experienced Engineering Manager to grow and lead our Software Infrastructure Team....SeniorFull timeLocal areaRelocation package$160k - $190k
...business decisions. Gather requirements from potential customers, engineering and construction companies, equipment manufacturers,... ...retire risks and use SB Energy’s Innovation Center for real‑world technology demonstrations. Assist first‑of‑a‑kind deployment into...SeniorWork at officeRemote workFlexible hours$199.9k - $320k
...About Us Visa is a world leader in payments technology, facilitating transactions between consumers, merchants, financial institutions... ...with you. Job Description Role summary The Sales Engineer (SE) is a technical sales specialist responsible for enabling...SeniorWork experience placementWork at officeLocal area$120.8k - $224.3k
Genentech is seeking a Technical Development Principal Engineer in South San Francisco, CA. The role involves ensuring robust clinical... ...designs. Responsibilities include process development, technology transfer, and collaborating with cross-functional teams. Candidates...SeniorRelocation package- ...POSITION TITLE:Senior Project Manager (Civil/Structural Engineering) Hinman Consulting Engineers, Inc. provides advice and solutions to protect people, operations... ...US General Services Administration, a Fortune 50 technology company, and the State of California. Mission...SeniorFull timeContract workWork at officeWorldwideFlexible hours
- ...Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause... ...used for more than 500,000 patients worldwide. As the Senior Manager, Device Quality Engineering , you will lead the global strategy for software...SeniorWork experience placementLocal areaImmediate startWorldwideRelocation
$233k - $285k
...Senior Solutions Engineering Manager, West Distributed At Cloudflare, we are on a mission to help build a better Internet. Today the company... ...of experience combined with genuine curiosity for our technology. Ultimately, you are passionate about technology, have...SeniorTemporary workLocal areaFlexible hours$260k - $275k
SENIOR PRINCIPAL SOFTWARE ENGINEER Saviynt is an identity platform built to power and protect the world at... ...right-level access to the digital technologies and tools they need to do their best... ...technologies such as Java, Spring Framework, REST and Microservices...Senior
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Director, Engineering and Technology (Holly Springs). Be the first to apply!
- data center chief engineer South San Francisco, CA
- hotel chief engineer South San Francisco, CA
- principal developer South San Francisco, CA
- senior civil engineer project manager South San Francisco, CA
- general engineer South San Francisco, CA
- senior principal engineer South San Francisco, CA
- chief engineer South San Francisco, CA
- senior chief engineer South San Francisco, CA
- engineering director South San Francisco, CA
- director software engineering South San Francisco, CA

