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Manufacturing Supervisor, NGS TE Production

Twist Bioscience

Twist Bioscience seeks a Manufacturing Supervisor to oversee NGS gene synthesis production in a high-throughput, automated lab. The role requires leading shift operators on molecular biology workflows, ensuring quality and compliance, and driving process improvements in a GMP/ISO-regulated environment.

Responsibilities

  • Manufacture custom gene products according to standard operating procedures in high-throughput environment
  • Lead shift operators, provide guidance on priorities, troubleshoot technical issues, and coordinate shift handoffs
  • Maintain detailed batch records, documentation, and regulatory compliance (ISO 13485, GMP standards)
  • Operate and calibrate semi-automated and automated molecular biology equipment
  • Identify production problems, recommend process improvements, and submit deviation and CAPA documentation

Requirements

  • Associate's or Bachelor's degree in Biology, Chemistry, or Biochemistry
  • Minimum 5 years laboratory experience in manufacturing environment
  • Proficiency with automated liquid handlers (Hamilton, Tecan) and molecular biology instrumentation
  • Demonstrated experience with GMP, ISO 13485, and LEAN manufacturing practices
  • Leadership experience with small laboratory teams and scientific problem-solving
  • Knowledge of LIMS/MES systems and sample tracking software
  • Ability to work shift hours (Wednesday–Friday, 7:00 pm–7:30 am) with alternate Saturday
Vacancy posted 2 days ago
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