Lead Scientist - Oligonucleotide Process Development
Amgen Inc
Amgen in Cambridge, MA is seeking a Principal Scientist in Oligonucleotides to lead manufacturing process development, drive capacity expansion, and manage technology transfers for oligonucleotide programs across development stages. You will mentor staff, collaborate with cross-functional teams to improve yield, ensure cGMP compliance, support regulatory filings, and advance innovative bioconjugate manufacturing approaches within a dynamic, science‑driven environment. #J-18808-Ljbffr Amgen
$136.8k - $167.2k
...a successful candidate you will join the sgRNA Process Development Group as part of the larger Oligonucleotide and Lipid Process Sciences team within Technical... ...small molecule synthesis; mentor and train junior scientists; and collaborate with stakeholders that support...SuggestedFull time$114.1k - $211.9k
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...developing antisense oligonucleotides (ASOs) to selectively... ...'s first medicine in development, zorevunersen, has demonstrated... ...are seeking a Senior Scientist, Sterile... ...oligonucleotide drug products and processes by ensuring the... ...to independently lead, design, conduct, and...Contract workTemporary workWork at office- Prime Medicine in Cambridge, MA is seeking a Senior Scientist / Senior Engineer to lead LNP process development, formulation, and scale‑up for our gene editing delivery programs. You will own bench‑to‑GLP/GMP process development, including formulation, process optimization...
$138k - $184.5k
About This RoleWe are looking for a talented and highly motivated Senior Scientist to join our growing Chemical Process Development (CPD) group. The ideal candidate will have demonstrated hands-on experience in an industrial laboratory, project management experience including...Contract workTemporary workLocal area- Amgen is seeking a Process Development Senior Scientist in Cambridge, MA to join the Biologics Pivotal Attribute Sciences team. You will develop and transfer analytical methods, lead protein characterization, and drive automation-ready workflows while supporting regulatory...
- Role Support development and scale-up of lipid nanoparticle (LNP) formulations for nucleic acid delivery, focusing on process optimization and enhancing LNP design. Responsibilities conduct formulation process development, optimize mixing parameters, encapsulation efficiency...
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...inspire you and empower you to shine? Join us as a Scientist, Process Analytics, Synthetic Molecule Process Development in our Cambridge office. At Takeda, we are... ...complex/multiple projects or functional areas through leading or influencing others. Influence and support...Minimum wageFull timeWork at officeLocal areaWorldwide- Takeda is seeking a Scientist, Process Analytics in Cambridge, MA to drive analytical method development for process chemistry and enable scale-up and tech transfer. The role leads analytical experiments and data interpretation to improve drug substance processes. You...
- ...Therapeutics in Bedford, MA is seeking a Senior Scientist, Sterile oligonucleotide drug product development to help drive formulation development and process scale-up for investigational medicines... ...will apply robust scientific methods, lead experiments, and contribute to...Contract workWork at office
- ...Amgen seeks a Principal Scientist to lead oligonucleotide process development and manufacturing innovation within the Process Development group. The role involves directing multidisciplinary teams on sustainable manufacturing processes, capacity expansion, and technology...Contract work
$55 per hour
...Title: Scientist 3 Process Development Location: Onsite Cambridge MA 02142 Duration: 6 Months with... ...development experience to join our Oligonucleotide/Peptide Purification Development team... ...training/mentoring of new employees lead pilot scale activities and collaborate...Contract work- Novartis in Cambridge, USA is seeking a Research Scientist I or II in Oligonucleotide Chemistry to synthesize, purify and characterize therapeutic oligonucleotides. You will work across discovery and development with a collaborative team to optimize methods and document...
$145k - $161k
Company Overview Prime Medicine is a leading biotechnology company dedicated to... ...and a clearly defined clinical development and regulatory path, and each expected... .... Position Summary The Senior Scientist / Senior Engineer, LNP Process Development will provide technical...Full timeContract workTemporary work$96.01k - $116.34k
...Senior Associate Scientist position supporting RNA drug substance programs from preclinical through early-stage development. The role involves optimizing in vitro transcription and synthesis processes, performing hands-on experimentation, and collaborating with research...- Novartis Institutes for BioMedical Research, Inc. is seeking a Principal Scientist to lead formulation development for complex biologics, including monoclonal antibodies and ADCs. The role involves guiding a team, shaping early development strategies, and partnering with...
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$108.5k - $201.5k
...Job Title: Principal Scientist I/II Position Location... .... As a Team Lead for the analytics team... ...as well as providing development opportunities for associates... ...group Foster streamlined processes and optimal use of... ...Abs, AAV, ADCs, oligonucleotides, CAR‑T’s. This entails...Local area- AbbVie in Cambridge, MA seeks a Senior Scientist I/II to advance siRNA therapeutics within the Biotherapeutics... ...delivery and drive RNA-based therapy development across multiple programs. Responsibilities include leading cross-functional research, developing delivery...
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...Discovery & Pre-Clinical/Clinical Development Job Sub Function:... ...Immunology Our Immunology team leads in the development of... ...best talent for a Principal Scientist Translational Science Program... ...committed to providing an interview process that is inclusive of our...Full timeContract workLocal areaImmediate start- Regeneron is seeking a Senior Toxicologist to lead nonclinical development programs with regulatory oversight and cross‑functional collaboration. The role requires deep GLP and regulatory expertise to design, conduct, and report studies in rodent and non‑rodent models...
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- ...AT Process Technologies (ATP) is a pioneering manufacturing company focused on the development and deployment of modular energetics production plants. Using breakthrough chemistry and automation that operates continuously and generates little to no waste, ATP is expanding...Permanent employment
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