Principal Investigator, Gastroenterology
Kinetic Clinical Research
Job Description
Job Description
About Kinetic Clinical Research
Kinetic Clinical Research (“KCR”) is a fast-growing, multi-site clinical research organization built by physicians and operators who understand the realities of modern clinical practice. Following the consolidation of several successful Southern California research sites, KCR is expanding its gastroenterology research portfolio and is seeking an entry level or an experienced Gastroenterologist to serve as a Principal Investigator (PI) and long-term clinical partner.
The Opportunity
This role is ideal for a gastroenterologist who wants to:
- Expand or transition into clinical research leadership
- Work in a supportive, well-staffed research environment
- Participate in a growing research platform with long-term upside
- Potentially progress toward profit-sharing or equity participation based on contribution, performance, and mutual alignment
Role Overview
As a Principal Investigator, you will lead and oversee GI related clinical trials, working closely with KCR’s experienced operations, regulatory, and recruitment teams. You focus on medicine and oversight — we handle the infrastructure .
Key Responsibilities
- Serve as Principal Investigator on gastroenterology clinical trials (e.g., IBD, NASH/MASH, IBS, GERD, motility, liver disease, or related indications)
- Provide medical oversight and ensure subject safety and protocol compliance
- Review and approve study protocols, informed consent documents, and safety reports
- Supervise Sub-Investigators and collaborate with CRCs and site staff
- Participate in Sponsor meetings, feasibility assessments, and monitoring visits
- Support patient recruitment and retention through clinical engagement
- Maintain compliance with FDA regulations, ICH-GCP, IRB requirements, and KCR SOPs
What We Offer
- Turnkey research infrastructure (experienced CRCs, regulatory, recruitment, pharmacy, and QA support)
- Access to active and upcoming GI studies with strong Sponsor relationships
- Flexible scheduling (part-time or per-diem arrangements available)
- Competitive per-study or hourly compensation
- Administrative and operational support so you can focus on clinical work
- A collegial, transparent leadership team that values physician input
Growth & Partnership Potential
KCR is building for the long term. For physicians who demonstrate strong leadership, study performance, and alignment with our mission, there is a clear pathway to expanded roles , including:
- Lead Investigator status across multiple studies
- Involvement in study selection and portfolio development
- Profit-sharing opportunities tied to site growth and performance
(This is not a promise or guarantee, but a genuine opportunity we actively pursue with the right partners.)
Qualifications
- MD or DO with Board Certification or Eligibility in Gastroenterology
- Active, unrestricted California medical license
- Prior Principal Investigator or Sub-Investigator experience preferred (but not required)
- GCP-trained or willing to complete GCP training
- Interest in clinical research, innovation, and collaborative growth
Why Physicians Choose KCR
- We respect your time and expertise
- We invest in systems and staff — not shortcuts
- We view investigators as partners, not vendors
- We are building something scalable, reputable, and physician-led
- ...creating long-term professional and financial opportunities for our investigators. We are expanding our dermatology research platform and... ...or board-eligible Dermatologist to join KCR as a Principal Investigator (PI) . The Opportunity This role is ideal...PrincipalHourly payDaily paidPart timeFlexible hours
- ...Principal Investigator (PI) Dermatology We are seeking an experienced and passionate Board-Certified Dermatologist to join our clinical research program as a Principal Investigator (PI). The Dermatology PI will play a key role in advancing clinical research, conducting...PrincipalHourly payContract work
- ...Degenkolb Engineers is seeking an Associate / Associate Principal for LA and Orange locations to lead the design and delivery of seismic structural systems, from concept to construction. This role blends technical depth with project leadership and client trust building...Principal
- We currently have career opportunities for experienced, self-determined, and highly motivated SURVEILLANCE INVESTIGATORS that would like to join our team of professionals in our efforts to deter and combat insurance fraud. The surveillance investigator position is a field...SuggestedBi-weekly payHourly payWork at office
- ...Principal Radar Systems EngineerAt RTX, the world's largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world's most complex problems. With our three market leading businesses, world-class operations...Principal
- BRIEF DESCRIPTION OF JOB DUTIES : Present product design solutions to customers at technical design reviews. Electrical design of FPGA, board, and system-level hardware. Support PWB layout activities. Create system, sub-system, interface, and protocol specifications...PrincipalFull time
$180k - $250k
...through automation, visibility, and exceptional user experiences. As we continue to scale, we're looking for experienced Staff and Principal Software Engineers who are passionate about designing distributed systems, mentoring engineers, and driving technical strategy...PrincipalRemote workVisa sponsorship$75k - $232k
...exciting opportunities and company perks await!Job Description:The Principal Quality Engineer for Supplier Operations is responsible for... ....Support Microchip factories and business units in the investigation and resolution of supplier-related quality issues through root...PrincipalPermanent employmentFull time$132.4k - $251.6k
...of the global market. Join us and help shape the future of aerospace and defense.Applied Signal Technology (AST) is seeking an Sr Principal Systems Engineer / ICT Lead who strives for excellence and has a passion to be part of a team that strengthens our nation and improves...PrincipalTemporary workWork experience placementWork at officeRemote workFlexible hours- ...Job Title Special Investigator (SI) works at the entry/training, journey, and full journey level to investigate re-active consumer complaints including complex complaints based upon the rules and regulations of the Contractors State License Law. The incumbent must...For contractors
- ...infrastructure, and commercial and residential development. We work hard. We play hard. We have fun. JOIN CANNON as a STRUCTURAL PRINCIPAL ENGINEER in IRVINE. Irvine offers warm weather, beautiful scenery, and is a top bicycling city with miles of on-road bicycle...PrincipalRemote workRelocation package
- AcaraSolutions in Cypress, CA is seeking a Senior Principal Algorithm Software Systems Engineer to lead real-time missile detection projects. You will own Kalman filtering and estimation techniques, guiding development from concept through validation and deployment in cluttered...Principal
- ...Job Title This position is located at the Orange Investigations Office in Orange. This Limited Term position may be extended to 24 months and may become Permanent. This is a Peace Officer position subject to P.O.S.T. requirements. Performing in a law enforcement...Permanent employmentFull timeWork at officeRelocation
- Office of Public Response is seeking a code enforcement inspector to ensure compliance with zoning, housing, dangerous building and related codes in Santa Ana. You will read plans, inspect structures, and enforce regulations to prevent blight and unsafe conditions. The...Work at office
$208.17k - $254.43k
Tracking Code4039Job DescriptionPosition Summary As a Managing Principal Engineer, you will manage, coordinate, and lead (conceptual) design on projects for the Southern California Division of Southland Industries. A large component of this role will be focused on client...PrincipalContract workWork at officeImmediate startFlexible hours$24 - $29 per hour
...Electric Vehicle) Referral Bonus Quarterly lunches Daily fresh fruit And a lot more! About The Position Position Summary The Fraud Investigator / Loss Mitigation Analyst is responsible for identifying, investigating, and resolving fraudulent activities and losses related...Hourly payContract workTemporary workWork at officeFlexible hours- ...Principal Algorithm Development Engineer Seeking a Principal Algorithm Development Engineer for a high growth space engineering contractor in Cypress, CA. The Algorithm Development Engineer would be responsible for serving as the primary technical authority for detection...PrincipalFor contractors
- ...Principal Analog Electrical EngineerSeeking a Principal Analog Electrical Engineer for a high growth Defense and Space development company in the Cypress, CA area. The Principal Analog Electrical Engineer would be responsible for design, development, modification and analysis...Principal
- It's fun to work in a company where people truly BELIEVE in what they're doing!Job Description: The Sr. Principal Information Security Architect is a strategic technical leader responsible for defining and driving enterprise security architecture across multi-cloud environments...PrincipalFull time
- Leonardo DRS in Cypress, CA is seeking a Senior Principal Algorithm Software Systems Engineer to lead the development of real-time detection and tracking algorithms for advanced defense systems. The role requires deep Kalman filtering expertise, strong ownership, and hands...Principal
$198k - $216k
...leadership, and a pay scale set at the 75th market percentile. To learn more, please visit our website: Job Description : Principals are leaders of the firm and are expected to mentor and develop technical staff, effectively manage engineering projects, and successfully...PrincipalWork at officeFlexible hours$95.5k - $181.7k
Job ID: 01870199Posted: Posted TodayStart Date: 2026-08-28Location: US-CA-FULLERTON-611 ~ 1801 Hughes Dr ~ BLDG 611Country: United States of AmericaTime Type: Full timeDate Posted:2026-08-28 Country:United States of America Location:US-CA-FULLERTON-611 ~ 1801 Hughes Dr...PrincipalContract workTemporary workWork experience placementWork at officeRemote workRelocation packageFlexible hours- ...integrity, and accountability throughout the Department of Homeland Security (DHS). In our dynamic environment, the OIG conducts investigations, audits, evaluations, and inspections to enhance program effectiveness and efficiency and to detect and prevent waste, fraud,...Work at office
$118.3k - $224.9k
...Principal Radar Systems EngineerAt RTX, the world's largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world's most complex problems. With our three market leading businesses, world-class operations...PrincipalTemporary workWork experience placementFlexible hours- ...medical conditions), and sexual orientation. Position Details Job Code #: JC-527942 Position #s: (***) ***-****-003 Working Title: Investigator Classification: INVESTIGATOR $6,339.00 - $8,558.00 A $7,306.00 - $10,609.00 B New to State candidates will be hired into the...Permanent employmentFull timeWork at officeLocal areaRemote work
- ...special trust placed in public servants. Position Details Job Code #: JC-527942 Position #(s): (***) ***-****-003 Working Title: Investigator Classification: INVESTIGATOR $6,339.00 - $8,558.00 A $7,306.00 - $10,609.00 B # of Positions: 1 Work Location: Orange...Permanent employmentFull timeWork at officeLocal areaRemote work
- Vallarta Supermarkets is seeking an Area Investigator Asset Protection to analyze and investigate shrink, policy violations, and theft across their stores. This role trains auditors, performs undercover work when needed, and may require plain clothes with full equipment...Flexible hours
$105k - $175k
Altasciences in Cypress, California is seeking a Sub-Investigator I to supervise clinical activities for assigned trials. You will ensure subject safety and protocol adherence, while also documenting events in compliance with Good Clinical Practices. The ideal candidate...$20 - $24 per hour
Surveillance Investigator Job Locations: US-CA-San Clemente | US-CA-Orange Overview Company Overview: Advance Your Career in Insurance Claims with Allied Universal Compliance and Investigation Services. Allied Universal Compliance and Investigation Services is the premier...Work experience placementWork at officeLocal area$118.3k - $224.9k
...shape the future of aerospace and defense. We are looking for Principal Systems Engineers in Algorithms to support the Joint... ...in performing data analysis and problem solving (e.g. anomaly investigation)Proficient technical writing and oral communication • Experience...PrincipalTemporary workWork experience placementWork at officeRemote workFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Investigator, Gastroenterology. Be the first to apply!


