Associate Researcher I (Dr Dubois' Lab) - Cell Developmental & Regenerative Biology

The Dubois Laboratory at the Icahn School of Medicine at Mount Sinai investigates the fundamental mechanisms of cardiac development, with a focus on understanding how the heart is built at the cellular and molecular level. Our research spans questions in cardiac progenitor specification, ventricular chamber morphogenesis, cardiomyocyte maturation, and congenital heart disease, using a combination of mouse genetics, stem cell models, and genomic and imaging technologies. We are a collaborative and collegial team passionate about uncovering the fundamental mechanisms that drive the formation and function of the heart.

The Dubois Laboratory is seeking a motivated and enthusiastic Associate Researcher I to join our team immediately. This is an excellent opportunity for an individual who is passionate about cardiovascular biology and eager to contribute to research in a dynamic and supportive environment. The successful candidate will work on a range of projects investigating fundamental questions in cardiac development and disease, and will have the opportunity to develop a broad and versatile technical skill set. We are looking for someone who thrives both working independently and contributing as part of a collaborative team.

• Perform mammalian cell culture, including maintenance of pluripotent stem cell lines and differentiated cardiac cell types
• Assist with mouse colony management, husbandry, and genotyping
• Conduct standard molecular biology techniques including PCR, cloning, Western blotting, immunofluorescence, and qRT-PCR
• Assist with tissue dissection, histology, and immunostaining on embryonic and adult cardiac tissue
• Maintain detailed and organized laboratory records and experimental documentation
• Contribute to the preparation of figures, protocols, and other materials supporting publications and grant applications
• Participate actively in laboratory meetings and contribute to a collaborative team environment
• Assist with general laboratory operations including ordering supplies and maintaining equipment
• Performs other related duties
• Bachelors or Masters degree in science or related field required
• No experience required. One year of research experience preferred.
• Highly Preferred:
• Hands-on experience with mammalian tissue culture techniques
• Familiarity with basic cell and molecular biology methods (PCR, gel electrophoresis, Western blotting, immunostaining)
• Experience with mouse husbandry, colony management, and genotyping
• Prior exposure to developmental biology and/or cardiac biology
• Experience with confocal microscopy or other imaging modalities
• Familiarity with flow cytometry/FACS
• Experience in a research laboratory setting beyond coursework

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Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

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