Sr. Systems Engineer

We anticipate the application window for this opening will close on - 10 Sep 2026

Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first - developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact.

A Day in the Life
The Neuroscience portfolio develops implantable and enabling technologies used to diagnose and treat disorders of the nervous system. Within this organization, Systems Engineering drives the definition, integration, verification, and validation of complex medical device systems that combine hardware, software, instruments, and clinical workflows. This role supports Neuromodulation technologies used to treat conditions through targeted stimulation of nerves in the brain, spine, pelvic, tibial, and peripheral nervous systems.

As a Senior Systems Engineer, you will lead and support system-level development activities across the product lifecycle for Neuromodulation products and enabling technologies. The role focuses on translating customer and business needs into system requirements, managing interfaces across hardware and software components, supporting design changes, and ensuring products meet user, quality, and regulatory expectations through verification, validation, and risk management activities.

Primary Responsibilities

• Lead system-level design, development, and integration activities for implantable devices, instruments, and enabling technologies.
• Translate customer, clinical, and business needs into stakeholder and system requirements with clear traceability throughout the development lifecycle.
• Define, analyze, and manage system architectures, interfaces, workflows, use cases, and functional requirements across hardware and software components.
• Lead system verification and validation activities, including test planning, execution, analysis, and documentation to demonstrate compliance with requirements.
• Conduct risk assessments and support identification and mitigation of technical risks, hazards, and failure modes.
• Evaluate field issues, change requests, and product performance data to identify root causes and implement engineering solutions.
• Collaborate with research and development, quality, regulatory, marketing, and project management teams to support system development and product improvements.
• Support concept development, formative evaluations, usability studies, and laboratory-based testing to assess system functionality and user workflows.

Required Qualifications

• Bachelor's degree with 4 years of relevant experience OR Master's degree with 2 years of relevant experience.
• Strong knowledge of Design Controls, including requirements development, verification, validation (V&V), and traceability throughout the product development lifecycle.
• Experience working within a Quality Management System (QMS) in a regulated environment.
• Experience collaborating cross-functionally with software, hardware, and multidisciplinary engineering teams.
• Experience with reliability engineering, verification and validation, or failure analysis.

Preferred Qualifications

• Formal education, training, or hands-on experience in Systems Engineering principles and methodologies.
• Experience in the medical device industry and familiarity with applicable regulatory requirements (FDA, ISO 13485, IEC 62304, etc.).

For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required.

Physical Job Requirements

The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.


The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.

U.S. Work Authorization & Sponsorship

At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment.


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Benefits & Compensation

Medtronic offers a competitive Salary and flexible Benefits Package
A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create. We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage.

Salary ranges for U.S (excl. PR) locations (USD):$110,400.00 - $165,600.00

This position is eligible for a short-term incentive called the Medtronic Incentive Plan (MIP).

The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others).

The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance, Health Savings Account, Healthcare Flexible Spending Account, Life insurance, Long-term disability leave, Dependent daycare spending account, Tuition assistance/reimbursement, and Simple Steps (global well-being program).

The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match, Short-term disability, Paid time off, Paid holidays, Employee Stock Purchase Plan, Employee Assistance Program, Non-qualified Retirement Plan Supplement (subject to IRS earning minimums), and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums).

Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico.

Further details are available at the link below:

Medtronic benefits and compensation plans

It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities.

If you are applying to perform work for Medtronic, Inc. ("Medtronic") in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.