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Staff Software Engineer

$140k - $175k

CareDx, Inc.

CareDx, Inc. is a leading precision medicine solutions company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. CareDx offers products, testing services, and digital healthcare solutions along the pre- and post-transplant patient journey, and is the leading provider of genomics-based information for transplant patients.

**Ideal candidate will commute to the Brisbane, CA location**

We are looking for a Staff Software Engineer with deep expertise in Laboratory Information Management Systems (LIMS) to design, configure, and scale software solutions that support complex laboratory workflows. This role is ideal for someone who has worked hands-on with LIMS platforms such as Labbit, LabAdvantage, or similar systems, and who understands the nuances of clinical, molecular, and diagnostic lab operations.

You will partner closely with laboratory stakeholders, product managers, and cross-functional engineering teams to translate real-world lab processes into reliable, compliant, and scalable software solutions.

Key Responsibilities
  • Lead the design, configuration, and customization of LIMS systems to support end-to-end laboratory workflows (sample accessioning, testing, results, reporting, QC, and data integration).
  • Serve as a technical subject matter expert for LIMS workflows, lab operations, and healthcare terminology.
  • Work directly with laboratory users to gather requirements, map workflows, and implement system configurations that improve efficiency and data quality.
  • Build and maintain custom extensions, integrations, and automation around LIMS platforms using modern software engineering practices.
  • Integrate LIMS with upstream and downstream systems (instruments, ELNs, EMRs/EHRs, data warehouses, APIs).
  • Ensure systems meet regulatory and compliance requirements (e.g., CLIA, CAP, HIPAA, 21 CFR Part 11 where applicable).
  • Review and improve existing LIMS configurations to support scalability, performance, and maintainability.
  • Mentor junior engineers and provide technical leadership across LIMS-related initiatives.
  • Collaborate with QA, DevOps, and product teams to support testing, validation, deployment, and ongoing support.
Required Qualifications
  • Education: Bachelor's degree in Computer Science Engineering, or related field (or equivalent experience)
  • Experience: 8 to 10+ years of professional software engineering experience, with significant hands-on work in LIMS environments.
  • Extensive experience configuring and customizing LIMS platforms such as Labbit, LabAdvantage, or comparable systems.
  • Strong understanding of laboratory workflows, including sample lifecycle management, testing processes, and results management.
  • Deep familiarity with healthcare and laboratory terminology, data standards, and operational constraints.
  • Experience building integrations and APIs (REST, HL7, FHIR, or proprietary lab/instrument interfaces).
  • Proficiency in at least one modern programming language (e.g., Java, C#, Python, JavaScript).
  • Strong SQL and data modeling skills, particularly for complex scientific or clinical datasets.
  • Ability to translate lab requirements into technical designs and system configurations.
  • Excellent communication skills and comfort working with both technical and non-technical stakeholders.
Preferred Qualifications
  • Prior experience in clinical diagnostics, molecular labs, or reference laboratories.
  • Experience with instrument interfacing and automation.
  • Familiarity with validation documentation and regulated software development.
  • Experience working in agile development environments.
  • Exposure to cloud-based LIMS or SaaS laboratory platforms.
What Success Looks Like
  • Laboratory teams trust you as a go-to technical partner who understands how the lab really works.
  • LIMS workflows are streamlined, reliable, and scalable.
  • Integrations "just work," reducing manual effort and errors.
  • The system supports compliance without slowing down innovation.
Additional Details:

Every individual at CareDx has a direct impact on our collective mission to improve the lives of organ transplant patients worldwide. We believe in taking great care of our people, so they take even greater care of our patients.


Our competitive Total Rewards package for US Employees includes:
  • Competitive base salary and incentive compensation
  • Health and welfare benefits, including a gym reimbursement program
  • 401(k) savings plan match
  • Employee Stock Purchase Plan
  • Pre-tax commuter benefits
  • And more!
  • Please refer to our page to view detailed benefits at

In addition, we have a Living Donor Employee Recovery Policy that allows up to 30 days of paid leave annually to a full-time employee who makes the selfless act of donating an organ or bone marrow.

With products that are making a difference in the lives of transplant patients today and a promising pipeline for the future, it's an exciting time to be part of the CareDx team. Join us in partnering with transplant patients to transform our future together.

CareDx, Inc. is an Equal Opportunity Employer-vets/disabled, and participates in the E-Verify program.

By proceeding with our application and submitting your information, you acknowledge that you have read our U.S. Personnel Privacy Notice and consent to receive email communication from CareDx.

***We do not accept resumes from headhunters, placement agencies, or other suppliers that have not signed a formal agreement with us.***

Certain jurisdictions require notice of how we use and protect your personal information. For more information, please read our Privacy Policy

#LI-Remote

This is the anticipated base salary range for candidates who will work in Brisbane, California. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and length of experience within the job, the type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states.

San Francisco Bay Area Roles

$140,000-$175,000 USD

This is the anticipated base salary range in the United States. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and length of experience within the job, the type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states.

Remote: US only roles

$112,000-$140,000 USD
Vacancy posted 3 days ago
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