Research Scientist

Brief Description Responsible for designing and executing experiments relating to the efficacy and mechanism of action of anticancer compounds with little supervision, with a specific focus on neuro‑oncology. Responsible for documenting and archiving experimental protocols, data, analyses, and conclusions according to established laboratory procedures. Expected to participate in communication of research into publications, conference presentations, abstracts, and patent applications. Self‑motivated and works under general supervision on multiple projects. This position is a full‑time laboratory‑based position. Essential Functions / Responsibilities Manage cell culture of cancers, including neurospheres. Perform in vitro efficacy, mechanism of action, target validation, and biomarker studies with cancer therapeutics, with an emphasis on CNS tumor models. Create stable cell lines with CRISPR and inducible expression of relevant biomarkers. Create or adapt reporter systems for relevant molecular targets. Present summary results for internal communications and external presentations. Support preparation of conference abstracts and manuscripts for publication as needed. Develop proper operational, data documentation, and troubleshooting procedures. Other responsibilities and projects that the company may assign. Required Knowledge, Skills & Abilities Ability to perform routine laboratory work, sit or stand at a computer for long stretches of time and type; frequently operates a computer and other office productivity machinery, such as a calculator, copy machine, and computer printer. Five or more years of industry or post‑doctoral experience on the bench dedicated to neuro‑oncology. Demonstrated expertise in neuro‑oncology biology, as well as therapeutics. Experience in oncology and pharmacology assays and techniques. Exceptional written and verbal communication including publications and conference presentations. Team player who is highly organized and able to manage multiple concurrent projects with minimal oversight. Forward‑thinking with the ability to anticipate challenges and proactively implement solutions. Computer proficient. Experience driving advancement of numerous projects simultaneously. Ability to identify and initiate tasks, set goals for completion, create timelines, and monitor progress to ensure completion. Strong sense of urgency to meet business needs. A positive, “hands‑on” approach to the position. Demonstrated ability to react and respond professionally to changing priorities and timelines. Demonstrated success in working in a matrix, cross‑functional environment. Demonstrated ability to communicate clearly both written and oral and work independently with a high level of attention to detail. Required / Preferred Education and Licenses Ph.D. in cancer biology, molecular/cell biology, biochemistry, pharmacology, or related fields, or master’s degree with relevant experience. Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. Compensation and Benefits (US Only) The full and complete base pay range is: $124,000.00 – $186,000.00. Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate’s expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis. Beyond base pay, the successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company’s Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz’s Long Term Equity Incentive Plan. The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401(k) retirement savings plan, and flexible paid vacation. For more information on our benefits offerings please visit #J-18808-Ljbffr