Staff Software Engineer, Scientific System of Record
$144k - $288kLila Sciences
Your Impact at LILA We are seeking a Staff Software Engineer to join our Scientific System of Record Team and help build the next-generation AI-driven scientific platform. You will focus on developing user interfaces, services, high-performance APIs, databases, and reliable systems that integrate advanced AI frameworks with complex scientific analytics and laboratory workflows. You’ll work closely with ML researchers, platform engineers, and scientists to develop systems that can handle diverse workloads and scale seamlessly, including structured SQL databases, data lakehouses, workflow engines, and lab execution environments. This is an opportunity to apply your deep front-end and backend expertise to a cutting-edge AI platform with real scientific impact. If you are passionate about building performant, elegant systems, we would love to hear from you. About The Team The Scientific System of Record Team (SSR) builds the memory layer for Lila's operations. It answers two questions:what did we plan to build? and what actually happened? These systems connect scientific intent to physical reality. Together with the data and automation teams, their systems ensure reproducibility and close the Design-Build-Test-Learn (DBTL) loop. What You'll Be Building User Interfaces and APIs: Design and build high-performance, secure, and well-documented UIs and APIs that integrate with AI-driven applications. Database Architecture and Scaling: Develop schemas and manage diverse data systems, including SQL, NoSQL, vector databases, and other emerging technologies, for performance and scalability. Application Development: Drive implementation of front-end and backend services with a focus on performance, maintainability, and reliability. Performance and Reliability: Diagnose and resolve system bottlenecks while ensuring high availability and low-latency performance across large-scale workloads. Cloud and Infrastructure: Leverage AWS services, Kubernetes, and modern DevOps practices to build and deploy production-grade systems at scale. Cross-Functional Collaboration: Work with ML researchers, engineers, and scientists to integrate data pipelines, APIs, and cloud infrastructure into scientific workflows. What You’ll Need to Succeed Bachelor’s or Master’s degree in Computer Science, Engineering, or related field. 6–8+ years of engineering experience building and deploying large-scale systems in production. Strong expertise in at least one of the following areas, with the ability to work across the stack: front-end engineering, backend engineering, or data modeling and system design. TypeScript, React, and Python: Strong experience with React and TypeScript is required; Python experience is strongly preferred. Databases: Strong experience with SQL, NoSQL, and emerging database technologies such as vector databases; proven track record in schema design, indexing, and query optimization. API Development: Proven ability to design and scale RESTful or GraphQL APIs with a focus on reliability and performance. Hands-on experience using AI coding assistants to improve engineering productivity. Scientific or Data-Intensive Domains: Experience working in life sciences, materials science, or other research-heavy or data-intensive fields. Communication and Collaboration: Strong listening skills and a proven track record of working cross-functionally with scientists, data engineers, and product teams; able to explain complex ideas to diverse audiences. Problem Solving: Proven ability to take ownership of complex technical challenges while balancing trade-offs between scalability, performance, and maintainability. Bonus Points For Cloud and DevOps: Hands-on experience with AWS, GCP, or Azure; strong understanding of Kubernetes, containerization, infrastructure as code such as Terraform or CloudFormation, and CI/CD pipelines such as GitHub Actions. Orchestration Systems: Experience with orchestration tools such as Flyte, Temporal, Airflow, Prefect, or similar systems. Experience building laboratory, scientific workflow, LIMS, ELN, data platform, or ML platform products. Experience designing systems that support auditability, traceability, reproducibility, data provenance, or regulated workflows. Compensation We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact. U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market. Expected Base Salary Range
$144,000—$288,000 USD
About LILA Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves. LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply. We’re All In Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy. A Note to Agencies Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.$10 per hour
Staff Software Engineer, Autonomous Freight Systems About Flexport: At Flexport, we believe global trade can move the human race forward. That’s why it’s our... ...not just execute on a spec. You have a proven track record of building data-heavy applications where high-...Suggested- Member of Technical Staff - Software Engineer Valthos | Posted Mar 3 Full-time Negotiable Advanced... ...deploy software and biological AI systems to safeguard humanity. The same AI architectures... ...frontier methods to the end users, scientific and technical. Your day-to-day...ScientificFull timeWork at office
$180k - $200k
...us on LinkedIn. AI Engineering @ Ironclad Ironclad... ...reliable, highly scalable software and services designed... ...: Proven track record of building, deploying... ...performance issues and ensure system health. Agile and... ...Base Salary Range - Staff: $210,000 - $235,000...SuggestedContract work$238k - $290k
...getting started. Role Overview As a Staff Software Engineer on the Site Reliability team at Harvey... ...infrastructure and product, owning the systems that keep our platform fast, secure, and... ..., or similar languages) Proven track record of diagnosing complex system problems...SuggestedRelocation package$150k - $300k
...Eureka AI, Tesla, OpenAI), Tri Dao (Chief Scientific Officer of Together AI), Dylan Patel (... .... Role Impact This is a generalist software engineering role focused on building the product... ...ML/AI workloads WebSocket / real‑time systems experience Open‑source contributions...ScientificWork at officeRemote workVisa sponsorshipRelocation packageFlexible hours- ..., ML researchers, and engineers to work together to move... ...of machine learning systems architecture and distributed... ...by enabling our scientific teams to flexibly conduct... ...systems design and software architecture. Identify... ...consistency. Solid track record of observable...ScientificWork at office
- ...array of tools being released daily. Staff Software Engineer / Technical Lead We're hiring a Staff... ...engineers. As the complexity of our systems and customer requirements continues to... ...across research, infrastructure, and scientific computing environments. The role...Scientific
$111.78k - $206.88k
...want to build amazing high-scale backend systems for Advertising using the latest... ...implementation? If you answered yes, then our Staff Software Engineer role on our ads engineering team may... ...interpersonal skills and a consistent record to work in a collaborative team...Full timeTemporary workPart timeLocal areaRelocation package$405k
...interpretable, and steerable AI systems. We want AI to be safe and... ...of committed researchers, engineers, policy experts, and business... ...an exceptional Senior Staff Software Engineer to join the Claude... ...experience with a clear track record operating at Staff or Senior...Work at officeRemote workVisa sponsorshipFlexible hours$500 per month
...to displace age-old legacy systems within financial institutions... ...positive, and past the point where engineering is about survival. Now it's... ...lasts. THE OPPORTUNITY The Staff Software Engineer role at interface.... ...just executed it A clear record of architectural wins:...Full time- ...in office) About our Engineering Teams We’re hiring across... ...you want to grow. Our software development is AI-... ...What You Will Do As a Staff Software Engineer, you... ..., with a proven track record of technical leadership... ..., distributed backend systems, ideally in the fintech...Bank staffWork at officeNight shift2 days per week
$231k - $314.35k
...Role Overview As a Software Engineer on the Product Engineering team at Harvey, you will own and... ..., Legal, and GTM teams to build secure systems that deliver value to our customers. We... ...TailwindCSS), Python, or related. Track record of building fast‑growing SaaS products....$230k - $285k
...was a machine learning research engineer at Scale AI . The rest of our... ...Our mission is to build the first system-of-action for go‑to‑market teams... ...are: You have 8+ years of software engineering experience and have a track record of shipping high‑quality products...$210k - $235k
...Engineering @ Ironclad Ironclad is the leading AI contracting platform... ...or company events. As a Staff+ Software Engineer at Ironclad, you'll... ...coding fundamentals and a track record of shipping high quality... ...design, and build features and systems Partner with quality...Work at officeRemote work$220k - $270k
...Staff Software Engineer page is loaded## Staff Software Engineerremote type: On-sitelocations: Chicago... ...in their workflows, learn their systems, and transform their expertise into reliable... ...into shippable technical scope* Track record of making pragmatic build-versus-wait...Temporary workRemote work$230k - $285k
...using AI, 3D data, and modern software experiences. We’re looking for a Staff Software Engineer to help scale our Core UX team,... ...initiatives, and help establish the systems, culture, and engineering... ...engineering priorities. A proven track record of leading complex, high-impact...Full timeFor contractorsWork at officeLocal areaFlexible hours- ...What you’ll do Own and evolve frontend systems that span multiple product areas, ensuring... ..., quality, and scalability Partner with engineering leadership, product, and design to shape... ...and/or React Native A strong track record of owning complex UI systems or frontend...Hourly payDaily paidMinimum wageWork at officeWork from homeHome officeFlexible hoursShift work
$225k - $320k
...Full Time · Department: Engineering (R&D) · Work type: On-... ...information into systems, chasing documents, doing... ...collaboration. Join a lean, staff-level team (ex-Affirm,... ...product manager and software engineer... ...experience. Proven track record of shipping user‑focused...Full timeWork at officeImmediate startRelocation$130k - $155k
...Current Opening – Staff Software Engineer The Staff Software Engineer is an experienced member of one of Dayspring’s engineering teams and reports... ...Project management experience that includes a track record of successful implementations and a focus on building repeatable...Full timeLive outWork at officeRemote work2 days per week3 days per week$189k - $210k
...Staff Software Engineer, Developer Productivity Async About Gusto At Gusto, we're on a mission to grow... ...by enhancing the tools and systems used by product engineers. You will focus... ...using Sidekiq and/or Kafka. Proven track record of improving developer productivity through...Full timeWork at officeLocal areaRemote work2 days per week3 days per week- ...with a query. Our in-house OLAP engine, Nova, processes trillions of... .... We’re looking for a Staff Software Engineer who wants to go deep... ...full stack of a modern OLAP system — query planning and execution... ...frameworks, or equivalent. Track record of driving significant cost optimization...Immediate startWorldwide
- ...interpretable, and steerable AI systems. We want AI to be safe and... ...of committed researchers, engineers, policy experts, and business... ...team is hiring a Senior Staff Software Engineer to serve as the technical... ...+ cross‑platform A track record of seeing a multi‑quarter technical...Visa sponsorship
$200k - $250k
...Health, we are building AI-driven software to empower healthcare... ...Role We are seeking a Fullstack Engineer to help us craft intuitive, high... ...for delivering scalable systems, collaborating on product development... ...frontend architecture Track record of delivering high-quality UI...Work experience placementPrivate practiceWork at office$220k - $260k
...Staff Software Engineer Location: Hybrid - Palo Alto Office Tuesday/Thursday The difference you will... ...engineering solutions, with a proven track record of leading large‑scale architectural... ...operational and workflow management systems. You are a power‑user of agentic...Part timeH1bWork at officeFlexible hours$250k
...everyday life. We're a stealth team of hardcore engineers, designers, and researchers discovering... ..., polish, and a highly visual design system that feels intentional in every... ...interaction patterns, accessibility). Proven track record making mobile apps feel instant under...Work at office$219.6k - $268.4k
...GoFundMe team is searching for our next Staff Software Engineer to help GoFundMe Pro team. One of... ...Design and build scalable full-stack systems across web applications, back end services... ...application performance metrics. Track record of identifying and implementing best...Full timeFlexible hours$175k - $240k
...About Edison Scientific builds and commercializes AI agents for science... ...team of top researchers and engineers across AI and biology to... ...and maintain a modular design system. Profile and optimize rendering... ...end engineering, with a track record of shipping performant, complex...ScientificWork at office$200k - $350k
...AI Engineer - Forward Deployed San Francisco, CA About Edison Scientific builds and commercializes AI agents for... ...years of professional software engineering experience, with a track record of shipping... ...comfort navigating complex systems, debugging issues in...ScientificWork at officeRemote work$144k - $240k
...reality — and we need engineers who want to solve problems... ...Principal / Principal Software Engineers to design... ...who can architect systems that don't exist yet —... ...cloud infrastructure into scientific workflows. What You'll... ..., and a proven track record of working cross-functionally...ScientificFull timeWork at officeLocal areaFlexible hours$228k - $285k
...Staff Software Engineer San Francisco, CA; Santa Clara, CA; Seattle, WA; New York, NY The Company... ...for private market data. Financial Systems Architecture: Designing resilient,... ...software engineering experience with a track record of high-level technical leadership....Full timeWork at officeImmediate start
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Staff Software Engineer, Scientific System of Record. Be the first to apply!
- visual systems engineer San Francisco, CA
- system engineer contract San Francisco, CA
- application system engineer San Francisco, CA
- system test engineer San Francisco, CA
- senior windows systems engineer San Francisco, CA
- lead system engineer San Francisco, CA
- system performance engineer San Francisco, CA
- senior staff systems engineer San Francisco, CA
- director systems engineering San Francisco, CA
- systems engineer San Francisco, CA


