Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Medical Director, Pulmonary Hypertension, Global Medical Affairs

$282.2k

Merck Sharp & Dohme

Job Description

Role Summary

The Global Senior Director Medical Affairs (GDMA) position resides in the Value & Implementation (V&I) organization, which includes GMSA as well as Outcomes Research.

The GDMA is a subject-matter expert (SME) in their area of responsibility (Pulmonary Hypertension) and responsible for driving execution of the Global Medical and Scientific Affairs (GMSA) portion for their assigned Therapeutic Areas (TA) as part of the Global V&I Plans. As a highly specialized SME, they bring business savviness to the organization, are important decision-makers, and will have a focus on the United States (U.S.), while also supporting the rest of world (ROW). The GDMA works as part of a high-performing, results-driven team, focused on executional excellence.

Responsibilities and Primary Activities

  • Drives execution of the annual V&I plan with medical affairs colleagues from key countries and regions with a focus on the U.S. Acts as an empowered partner, making informed decisions with a strategic and agile mindset.
  • Serves as the SME and connector across assigned therapeutic areas, translating global scientific platforms into actionable Medical Value Narratives (MVNs). Actively engages with country-level stakeholders—including medical advisors, payers, and scientific leaders—to ensure strategic alignment and support local data generation, congress planning, and advisory boards.
  • Serves as the medical representative within Product Development sub-teams (including Clinical, V&I, Commercial, Publications, and Label), leveraging the V&I GMSA vision to drive strategic planning, outcome delivery, and tactical execution. Communicates pertinent information to stakeholders (e.g., Executive Director Medical Affairs (EDMA), Regional Strategy Leads (RSL), Regional Director Medical Affairs (RDMA), U.S. Director Medical Affairs (US DMA), Payor and Access Strategy Leads (PASLs)) to inform and influence country and regional planning.
  • Acts as the subject-matter expert, collaborating closely with V&I Outcomes Research (VIOR), Policy, Commercial, and Market Access teams to identify and address opportunities and barriers in key countries.
  • Serves as a strategic partner for Big Country Markets (U.S., China, Japan) with no RDMA role.Plays a pivotal role in bridging global strategy with local execution, including understanding the needs of the U.S. Market. Proactively collaborates with the US DMA and equivalent roles in China and Japan, ensuring that country-specific insights are integrated into the global V&I plans and that global strategies are contextualized for local relevance.
  • Consolidates actionable medical insights from countries and regions.
  • Engages with a network of international scientific leaders and other key stakeholders (therapeutic guideline committees, payers, public groups, government officials, medical societies) about our company’s emerging science, building an important network and partnership internally and externally. Monitors external changing environment in partnership with the competitive intelligence (CI) team.
  • Organizes global expert-input events (advisory boards and expert-input forums) to answer our company’s questions about how to develop and implement new medicines or vaccines.
  • Collaborates with Global Human Health (commercial) executive directors to inform of the GMSA portion of V&I plans to ensure alignment, while independently leading the execution of these plans.
  • Organizes global symposia and educational meetings.
  • Supports key countries with the development of local data-generation study concepts and protocols when requested.
  • Reviews Investigator-Initiated Study proposals from key countries (ex-U.S.) prior to headquarters submission and in collaboration with RDMAs, while also serving as a review panel member on TA-specific out company Investigator Studies Programs (MISPs) to support the Executive Director Scientific Affairs (EDSA) review process.
  • Manages programs (patient support, educational or risk management) to support appropriate and safe utilization of our company medicines or vaccines.
  • Demonstrates and champions our company’s Ways of Working, emphasizing innovation, medical modernization, defining team priorities, and focusing on the impact to the patient.
  • Manages assigned budget with strong financial stewardship, ensuring delivery within a 3% variance. Responsible and accountable for making informed decisions when budgets change throughout the year.

Required Qualifications, Skills and Experience:

Minimum

  • M.D., Ph.D. or Pharm.D. (M.D. preferred) and recognized medical expertise.
  • Experience in country/region medical affairs or clinical development (Pulmonary Hypertension therapeutic area experience is preferred.)
  • Strong prioritization and decision-making skills.
  • Ability to effectively collaborate with partners across divisions in a matrix environment.
  • Excellent interpersonal, analytical, and communication skills (written and oral) in addition to results-oriented project management skills.

Preferred

  • At least three years regional medical affairs experience (e.g., Regional Director Medical Affairs) with proven track record of contribution to medical-affairs strategies.
  • Customer expertise, especially of scientific leadership and other key stakeholders (payers, public groups, government officials, medical professional organizations), in the assigned therapeutic area.

Required Skills:

Cardiology, Communication, Medical Affairs, Pharmaceutical Industry, Pulmonary Arterial Hypertension, Strategic Planning

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The primary location for this posting is:

USA - New Jersey - Rahway

Where required by law, the compensation range for this role is provided below.

The salary range for the primary location of this role is:

$282,200.00 - $444,200.00

This range reflects the Company's reasonable expectation of the base salary applicable to this role at the time of posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at .

Additional location(s): Please note the salary range above applies to the Primary Location of the position. Where a role has other listed locations, different compensation guidelines may apply. You may find the salary ranges for additional locations below. If the salary range is not listed for the location you are applying to, our Talent Acquisition team will provide further information to you relevant to your location.

Additional location(s) Compensation Information:

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

50%

Flexible Work Arrangements:

Remote

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

n/a

Job Posting End Date:

11/5/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Summary
  • Location: USA - New Jersey - Rahway; USA - Pennsylvania - North Wales (Upper Gwynedd)
  • Type: Full time
Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Senior Medical Director, Pulmonary Hypertension, Global Medical Affairs in North Wales, PA vacancy
  • $282.2k

    Job DescriptionRole SummaryThe Global Senior Director Medical Affairs (GDMA) position resides in the Value & Implementation (V&I) organization,...  ...matter expert (SME) in their area of responsibility (Pulmonary Hypertension) and responsible for driving execution of the Global... 
    Senior
    Full time
    For contractors
    Local area
    Flexible hours

    Merck Sharp & Dohme (MSD)

    North Wales, PA
    4 days ago
  • $178k - $307.05k

     ...Communications & Corporate/External Affairs Job Sub Function Multi-Family Communications...  ...the best talent to join our team as a Senior Director, Global Immunology Communications & Public...  .... Partner closely with R&D, Medical Affairs and Commercial leaders to communicate... 
    Senior
    Local area
    Immediate start

    6085-Janssen Global Services, LLC Legal Entity

    Spring House, PA
    3 days ago
  • The Senior Manager Global Regulatory Affairs CMC - Biological & Non-Biol. Products is responsible for:Partnering closely with CSL’s R&D, Manufacturing,...  ...continually refine ways in which products can address unmet medical needs and help patients lead full lives.CSL Behring... 
    Senior
    Full time
    Local area
    Flexible hours

    CSL

    Valley Forge, Montgomery County, PA
    1 day ago
  • $317k - $409k

    Position Overview:The Senior Medical Director, Global Clinical Program Leader (GCPL) is a critical role within Clinical Development. The Senior GCPL isaccountable for the design and execution of the clinical strategy to support the development of a medicine, aligned with... 
    Senior
    Odd job
    Full time
    Relocation package
    Free visa

    CSL

    Valley Forge, Montgomery County, PA
    2 days ago
  • Johnson & Johnson Innovative Medicine is seeking a Senior Principal Scientist, CMC Regulatory Affairs - Combination Products. This hybrid role can be located...  ...teams, and influence regulatory decisions globally across multiple programs. #J-18808-Ljbffr Johnson &... 
    Senior

    Johnson & Johnson Co.

    Spring House, PA
    5 days ago
  •  ...Johnson & Johnson is seeking a Director, Global Public Affairs to lead strategic public affairs initiatives across Oncology, Immunology, or Neuroscience within J&J Innovative Medicine. Hybrid role in Titusville, Raritan, New Brunswick, Spring House with global responsibilities... 

    Johnson Johnson

    Spring House, PA
    19 hours ago
  •  ...Medical Director RheumatologyWe are searching for outstanding talent for Medical Director Rheumatology...  ...team within the US Immunology Medical Affairs organization located in Horsham, PA....  ...) as well as partners in US and Global Medical Affairs, Real World Value and Evidence... 
    Work at office
    Local area
    Remote work
    2 days per week

    J&J Family of Companies

    Horsham, PA
    4 days ago
  •  ...CSL Behring seeks a Senior Manager, Program Management to drive integrated execution of Medical Affairs priorities within the portfolio. You will lead end-to-end program management...  ...and governance, ensuring alignment across global, regional teams and key functions.... 
    Senior

    BioSpace, Inc.

    King of Prussia, PA
    2 days ago
  •  ...CSL Plasma in King of Prussia, PA seeks a Senior Manager, Program Management to drive integrated execution of Medical Affairs priorities across the portfolio. You will lead...  ...strategy documents. The role partners with Global and Regional Medical Affairs leadership and... 
    Senior

    CSL Plasma

    King of Prussia, PA
    1 day ago
  • $117k - $184.2k

    Job Description SENIOR SCIENTIST (R3) REGULATORY CMC - SYNTHETIC MOIETIES...  ...robust, phase-appropriate global Regulatory CMC strategies for...  ...Process Chemistry, Regulatory Affairs Management, Regulatory CMC,...  ....- Available benefits include medical, dental, vision healthcare and... 
    Senior
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co.

    North Wales, PA
    2 days ago
  •  ...Merck seeks a Senior Director of Clinical Science for Breast Oncology to lead strategic clinical science initiatives across multiple...  ...collaboration skills across regulatory, biostatistics, safety, and medical affairs functions Demonstrated ability to standardize processes... 
    Senior

    Merck

    Upper Gwynedd, PA
    13 days ago
  • Johnson & Johnson in Horsham, PA, is seeking an Associate Director, Scientific Communications, Global Immunology Medical Affairs, with a hybrid work arrangement and onsite collaboration plus remote flexibility. The role supports Immunology medical affairs in advancing... 
    Senior
    Remote work

    Johnson Johnson

    Horsham, PA
    5 days ago
  • $282.2k

     ...a passionate and experienced Senior Principal Scientist specializing...  ..., regulatory affairs, statistics, and manufacturing...  ....Assist the Senior/Executive Director in ensuring that appropriate...  .... Available benefits include medical, dental, vision healthcare and... 
    Senior
    Full time
    For contractors
    Local area
    Worldwide
    Flexible hours

    Merck Sharp & Dohme (MSD)

    North Wales, PA
    2 days ago
  • $190.8k - $300.3k

     ...Improvement minded Regional Medical Scientific Director (aka Medical Science...  ...MD) Director Level Medical Affairs position and therapeutic and...  ...and corporate policies and Global Medical Scientific Affairs...  ...Skills: Chronic Obstructive Pulmonary Disease (COPD), Clinical Immunology... 
    For contractors
    Work at office
    Local area
    Remote work
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co., Inc.

    North Wales, PA
    3 days ago
  • $137k - $235.75k

     ...Medicine R&D is recruiting for a Senior Principal Scientist, CMC Regulatory Affairs - Combination Products. This position...  ...for post-approval programs, and Global Regulatory Team. This role will also...  ...of global combination product and medical device regulatory requirements and... 
    Senior
    Local area
    Immediate start

    Johnson & Johnson Co.

    Spring House, PA
    5 days ago
  • ICON is seeking a Senior Director, Regulatory Affairs to lead global regulatory strategy for the organization’s therapeutic area teams and manage a large regulatory staff. You will drive submissions, provide regulatory guidance, and collaborate with cross-functional colleagues... 
    Senior

    Regulatory Jobs

    Center Square, PA
    2 days ago
  •  ...metabolic liver and cardiometabolic therapies. The role involves medical oversight of first-in-human through early Phase 2 studies,...  ...regulatory, and commercial functions. Responsibilities Serve as global medical lead and monitor for early-phase interventional studies... 
    Senior

    Madrigal Pharmaceuticals

    Conshohocken, PA
    a month ago
  •  ...BCBS Global Solutions is seeking a Medical Director to lead physician-led case management across global operations. You will guide daily clinical reviews, collaborate with leadership, and drive provider engagement and quality improvements for international members.... 

    BCBS Global Solutions

    King of Prussia, PA
    4 days ago
  • $199k - $343.85k

     ...searching for outstanding talent for Medical Director, Dermatology and Respiratory to join the...  ...strategy, Good Clinical Practice, and global regulatory requirements. Serve as medical...  ...e.g. asthma, chronic obstructive pulmonary disease (COPD), chronic rhinosinusitis... 
    Local area
    Immediate start

    Johnson Johnson

    Spring House, PA
    1 day ago
  • $258.83k - $293.48k

     ...the fight against MASH.Madrigal’s medication, Rezdiffra (resmetirom), is a once-...  ...the right time, in the right way.The Senior Director of Regulatory Affairs CMC provides highly strategic,...  ...Authorities on CMC-related topics.Provides global regulatory input and support to... 
    Senior
    Minimum wage
    Full time
    Work at office
    Local area
    Flexible hours
    3 days per week

    Madrigal Pharmaceuticals

    Conshohocken, PA
    2 days ago
  •  ...MSD is seeking a Senior Director of Data Collection Data Steward to set strategy, govern data standards, and lead the Standards team. You will drive enterprise metrics, manage budgets, and communicate outcomes to executives while representing the company externally.... 
    Senior

    Jobleads-US

    North Wales, PA
    4 days ago
  •  ...Madrigal is seeking a Senior Director, Clinical Operations to provide strategic and operational leadership for global Phase I‑IV clinical trials and development programs. You will ensure delivery against timelines, quality, budget, and regulatory requirements while maintaining... 
    Senior

    Jobleads-US

    Conshohocken, PA
    4 days ago
  • $262.06k - $306.73k

     ...fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is...  .... Role Overview The Senior Director, Clinical Operations provides...  ...execution, and oversight of global Phase I-IV clinical trials...  ...Clinical Development, Regulatory Affairs, Data Management, Project... 
    Senior
    Minimum wage
    Full time
    Local area
    Flexible hours

    Jobleads-US

    Conshohocken, PA
    4 days ago
  •  ...Job Description The Senior Director, Data Collection Data Steward serves on the GCDS Leadership...  ...delivery, and mentoring of the Global Clinical Data Standards team. Act as a...  ...Study Design Available benefits include medical dental vision healthcare and other... 
    Senior
    Local area
    Worldwide
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Jobleads-US

    North Wales, PA
    5 days ago
  •  ...Senior Director, Regulatory Affairs ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines...  ...incentives Health and wellbeing programmes including medical, dental, and vision coverage where applicable... 
    Senior

    Regulatory Toolkit

    Center Square, PA
    2 days ago
  • $159k - $274.85k

     ...Associate Medical DirectorAt Johnson & Johnson, we believe...  ...The Associate Medical Director contributes medical and...  ..., with appropriate senior guidance.Participate in...  ...to work effectively in global, cross-functional, and...  ...Market Research, Regulatory Affairs Management, Research... 
    Immediate start

    J&J Family of Companies

    Spring House, PA
    19 hours ago
  • $194k - $334.65k

     ...Medical Director, Rheumatology Clinical DevelopmentAt Johnson & Johnson, we believe health is...  ...recommendation.Demonstrated effectiveness in global, cross-functional, and matrixed teams....  ..., Market Research, Regulatory Affairs Management, Research Ethics, Scientific... 
    Local area
    Immediate start

    J&J Family of Companies

    Spring House, PA
    4 days ago
  • $173.2k - $272.6k

     ...Basic Functions & Responsibility: The Global Clinical Supply (GCS) organization is within...  .... Primary Activities: The Director, GCS Continuous Improvement, will be accountable...  ...of benefits. Available benefits include medical, dental, vision healthcare and other insurance... 
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co. Inc

    Lansdale, PA
    1 day ago
  • $190.8k - $300.3k

     ...Job Description The Regional Medical Scientific Director (RMSD) - Cardiovascular & Metabolism is a...  ...research studies. Upon request from Global Clinical Trial Operations (GCTO): Identify...  ...from Global Center for Scientific Affairs (GCSA): Enhance the comprehension of... 
    For contractors
    Work at office
    Local area
    Remote work
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    MSD

    North Wales, PA
    2 days ago
  • Merck & Co., Inc. is seeking a senior leader to oversee a field-based medical team in Oncology RMSD. You will guide recruitment, training and performance management, while aligning disease state support plans with corporate strategy. You will manage regional budgets, lead... 
    Senior
    Remote job

    Merck & Co.

    North Wales, PA
    5 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Medical Director, Pulmonary Hypertension, Global Medical Affairs. Be the first to apply!