Biologics Process Research & Development Scientist

Biologics Process Research & Development (BPR&D) within our Company's Research Laboratories is on a mission to rapidly deliver biotherapeutics to patients by efficiently developing innovative, robust manufacturing processes and technologies. To achieve this, we work closely with colleagues in Discovery, Pre-clinical, Early Development, Analytical, Formulation, and Commercial Manufacturing while providing an inclusive environment for all. Beyond process development for pipeline biologics, we innovate and build next generation biomanufacturing technologies. Examples include investments for development of continuous manufacturing, green and sustainable processes, and proprietary technology platforms. We actively publish and engage with the scientific community to influence the field. Biologics Process Research & Development ( BPR&D) includes three lab-facing technical functional areas: Process Cell Sciences (PCS), Upstream Process Development (UPD) and Downstream Process Development & Engineering (DPDE). This job posting covers opportunities for all three functional areas. We are actively looking for highly motivated people with a passion for innovation and interest in contributing to one or more of the three technical functional areas mentioned above. As a Scientist in Biologics Process Research & Development ( BPR&D), you will work with immensely creative and collaborative team members to design and develop robust processes in support of early- and late-stage biologics. You will innovate to support our company's biologics pipeline and production platforms through rigorous scientific principles. You will have the opportunity to apply and integrate innovation into biologic process sciences to establish our company as the industry leader in next-generation biologics manufacturing. You may also be expected to contribute to additional areas of interest such as biophysical, reactor, process, economic and/or multivariate modeling as we are committed to leveraging digital ways of working to enhance our ability to design robust processes. Responsibilities include but are not limited to: Develop innovative and disruptive technologies for next-generation biologics manufacturing processes Develop and characterize robust clinical processes capable of delivering multi-kilogram quantities of therapeutics Design and conduct experiments related to cell-line development, upstream or downstream bioprocessing Integrate unit operations with relevant process control and monitoring platforms Collaborate across Biologics Process Research & Development BPR&D, process analytics, and other functional areas in research and manufacturing to advance the biologics pipeline Conduct laboratory- and/or pilot-scale studies to support scale-up and technology transfer to manufacturing sites Contribute to a safe and compliant laboratory work environment

MINIMUM EDUCATION REQUIREMENTS:

Education: Bachelor's Degree with 2+ years of relevant experience or master's degree in chemical/Biochemical/Biomedical Engineering, Biotechnology, Biochemistry, Molecular Biology, or related fields with research background in molecular biology, cell culture or protein purification

REQUIRED EXPERIENCE AND SKILLS:

Experience with one or more of molecular biology, protein expression, mammalian cell culture, protein purification, biochemical engineering, or analytical technologies Scientific understanding of the engineering principles behind recombinant protein production and purification Ability to comprehend and execute experiments independently Ability to organize, communicate, analyze, and present experimental data to drive conclusions and further study designs Knowledge of aseptic technique, protein biophysical properties, and general protein laboratory practices Demonstrated ability to independently prepare technical documents and scientific presentations to capture development progress, scientific investigations, and technology development output Basic understanding of statistical methods and data analysis tools Strong passion and commitment to integrate science and innovation into biologic process development Ability to excel in a collaborative and matrix environment

PREFERRED EXPERIENCE AND SKILLS:

Demonstrated capabilities in understanding and operating bioanalytical techniques to characterize microbial or cell culture processes Ability to think critically with excellent problem solving and troubleshooting skills High throughput screening, automated bioreactor systems, and liquid handlers Experience with process transfer to clinical or commercial manufacturing facilities Knowledge of process control and workflow automation tools Strong foundation in statistical analysis, design of experiments, data science, computational modeling Required Skills: Aseptic Technique, Aseptic Technique, Bioanalytical Techniques, Biomanufacturing, Bioreactor Operation, Cell Culture Process Development, Cell Cultures, Conducting Experiments, Cross-Functional Teamwork, GMP Compliance, High Throughput Screening HTS Systems, Mammalian Cell, Mammalian Cell Culture, Manufacturing Processes, Microbial Fermentation, Molecular Biology, Optimism, Process Optimization, Process Scale Up, Process Scheduling, Product Development, Protein Expression, Protein Purifications, Technical Leadership, Technical Transfer {+ 2 more} San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully- Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic VISA Sponsorship: No Travel Requirements: 10% Flexible Work Arrangements: Not Applicable Shift: Not Indicated Valid Driving License: No Hazardous Material(s): N/A Job Posting End Date: 10/1/2026 *A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Requisition ID:

R396516

#J-18808-Ljbffr Merck & Co.