CNC Programmer / Operator Lead

At a Glance

• Company: Repligen
• Location: Shrewsbury, Massachusetts
• Job Type: Full-Time
• Salary Range: $85,000 – $100,000 per year (DOE)
• Shift: Day Shift (flexible depending on facility needs)
• Overtime: As needed during production ramp-up
• Experience Level: Senior / Lead
• Industry: Bioprocessing / Life Sciences Manufacturing

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Why This Role Exists

Repligen is launching a new manufacturing facility in Shrewsbury, MA , and this role is critical to building a strong CNC programming foundation from the ground up.

As the Lead CNC Programmer , you’ll help establish programming standards, support new equipment installs, and mentor a growing team—playing a direct role in scaling production for life-saving biologic therapies used worldwide.

This is not a “sit behind the desk” role. It’s hands-on, technical, and influential.

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The Work You’ll Be Doing

In this role, you will:

• Develop, modify, and optimize CNC programs for milling, turning, and multi-axis machines
• Serve as the technical lead for CNC programming and machining strategy
• Review and approve CNC programs, setups, and tooling selections
• Lead program prove-outs, first articles, and production ramp-ups
• Partner with Engineering on DFM and new product introductions
• Establish programming standards, documentation, and setup sheets
• Mentor and train CNC programmers and machinists
• Support safety, quality, and regulatory compliance
• Drive continuous improvement and lean manufacturing initiatives

You’ll have real ownership over how CNC programming is done at this facility.

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Machines, Controls & Software

You’ll work directly with equipment such as:

• Machines:
  • NexTech CNC Router
  • Laguna CNC Router
• Controls: CNC router controls (machine-specific)
• CAM Software: Mastercam, Fusion 360, SolidWorks CAM
• Inspection: First article and in-process inspection support

This role will also help shape programming standards as additional equipment is brought online.

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What We’re Looking For

Required

• 5+ years of CNC programming experience in a manufacturing environment
• Advanced proficiency with G-code and CAD/CAM software
• Strong knowledge of machining processes, tooling, materials, and GD&T
• Experience supporting new equipment installs or facility start-ups
• Proven ability to mentor others and solve machining problems hands-on

Preferred (Not Required)

• Experience in regulated manufacturing environments
• Exposure to multi-axis machining strategies
• Background supporting production ramp-ups or greenfield facilities

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Materials You’ll Work With

• Stainless steels
• Aluminum alloys
• Engineering plastics
• Other precision manufacturing materials

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Why Machinists & Programmers Like Working Here

• Brand-new manufacturing facility
• Opportunity to build systems and standards , not inherit bad ones
• High-impact work supporting life-saving biologic therapies
• Cross-functional collaboration with engineering and quality
• Strong emphasis on quality, safety, and craftsmanship
• Real leadership path as the site scales

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Pay, Benefits & Schedule

• Salary: $85,000 – $100,000 DOE
• Medical, dental, and vision insurance
• 401(k) with company match
• Paid time off and holidays
• Long-term career growth in a mission-driven manufacturing environment

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Apply

Interested CNC Programmers ready to step into a technical leadership role can apply directly through hireCNC .

Apply now or save this job to come back later.