Clinical Research Nurse I

Clinical Research Nurse I (PRN) - Lenexa, KS (Onsite)

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

Position : Clinical Research Nurse

Location : Lenexa, Kansas (KS)

Full Time, Day Shift - 10 & 12-hour shifts available, 40-hour/week.

Are you a Registered Nurse looking for a role where your clinical expertise advances new treatments that improve patient outcomes? Join ICON as a Clinical Research Nurse , where your work supports scientific progress and helps bring innovative therapies to patients who need them.

The Clinical Research Nurse supports the safe, compliant execution of Phase 1 clinical trials with healthy volunteers in an on-site clinic setting. This role performs core nursing tasks (vitals, IVs, EKGs, injections, dosing, blood draws), and adheres to clinical research protocols that vary by trial. Prior research experience is not required —training is provided. ADNs are accepted ; candidates must hold an active, unrestricted RN license .

What You Will Do

As a Clinical Research Nurse, you will:

• Perform nursing procedures per protocol and orders: vitals, IV starts, EKGs, injections, dosing, phlebotomy.

• Conduct rounds across multiple concurrent studies throughout the shift (e.g., vitals on one study, blood draws on another).

• Document assessments, procedures, and events (AEs) thoroughly and accurately in study systems.

• Identify and open Adverse Events (AEs) when appropriate; SAEs are rare in the clinic’s healthy-volunteer setting.

• Support adherence to ICH-GCP, SOPs, and protocol requirements; escalate issues promptly.

• Collaborate with multidisciplinary teams; act as shift lead when trained/assigned.

• Provide clear communication to participants and team; follow all provider orders (MD/PA/NP).

ICON’s Clinical Research Nurses enjoy

• Clear schedules and an organized, structured clinical environment.

• A supportive team environment with well-defined processes.

• Professional growth opportunities in research, leadership, education, or coordination.

• Work that contributes directly to the development of future treatments.

Your Profile

• Licensed RN (ADN or BSN); active license to practice in Kansas

• Clinical nursing experience; no prior research experience required (training provided).

• Competence in core clinical skills: IVs, EKGs, injections, phlebotomy, vital signs .

• Strong clinical judgment, attention to detail, and documentation accuracy.

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What ICON can offer you:

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements

• A range of health insurance offerings to suit you and your family’s needs.

• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.

• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.

• Life assurance

• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site ( to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here (

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here ( to apply