Clinical Trial Manager, Oncology

Reference: 630982Posted: 2026-09-16Location: Philadelphia, PennsylvaniaCompany: Planet Pharma GroupContact: ApplicationsEmail: View email address on us.fitly.work OverviewA growing clinical-stage oncology biotech company is seeking an experienced Clinical Trial Manager (CTM) to lead the execution of early-phase oncology clinical trials. This individual will play a critical role in managing study start-up, CRO oversight, enrollment activities, vendor management, and day-to-day trial operations across Phase 1 and Phase 2 programs.The successful candidate will have a proven track record managing oncology studies within small biotech environments and will thrive in a fast-paced, hands-on culture where team members are expected to contribute across multiple functions. This role will initially oversee a Phase 1 study in start-up in Australia and work closely with internal and external stakeholders to ensure successful execution.This is a contract opportunity with the potential to convert to a permanent position for the right candidate.Key ResponsibilitiesLead the operational management of Phase 1 and Phase 2 oncology clinical trials from study start-up through closeout.Oversee a Phase 1 study currently entering start-up activities in Australia.Manage CROs, vendors, and clinical service providers to ensure delivery of study milestones, quality, and timelines.Track study progress, enrollment performance, site activation, and key operational metrics.Coordinate study start-up activities, including site selection, site initiation, regulatory submissions, and vendor implementation.Serve as the primary operational point of contact for internal study teams, investigators, CROs, and external partners.Develop and maintain study timelines, risk mitigation plans, and project tracking tools.Monitor study budgets, forecasts, and vendor spending in partnership with leadership and finance teams.Ensure protocol compliance and adherence to GCP, ICH guidelines, and company SOPs.Identify and proactively resolve operational challenges impacting study execution.Facilitate study team meetings and provide regular updates on study status, risks, and milestones.Support inspection readiness and audit activities as required.Required QualificationsBachelor’s degree in Life Sciences, Nursing, or a related field; advanced degree preferred.Significant clinical operations experience within biotechnology, pharmaceutical, or CRO organizations.Proven experience managing early-phase oncology clinical trials, including Phase 1 studies.Strong background in immuno-oncology and solid tumor clinical development.Demonstrated expertise in study start-up, CRO oversight, vendor management, and global study execution.Experience monitoring enrollment, timelines, budgets, and clinical trial performance metrics.Working knowledge of ICH-GCP guidelines and global clinical trial regulations.Excellent project management, organization, communication, and problem-solving skills.Ability to work independently in a remote environment while collaborating effectively across functions.Preferred QualificationsExperience working within small, emerging biotechnology companies.Prior management of studies conducted in Australia or other global regions.Experience supporting Phase 1, Phase 2a, and Phase 2b oncology programs.Strong understanding of operational challenges unique to early-stage biotech organizations.Proximity to the Greater Philadelphia area and ability to attend occasional onsite meetings preferred.