Analytical Development Scientist

The Analytical Development team is seeking a highly motivated and scientifically curious professional to support the development of small molecule drug substances and drug products. This role will focus on developing innovative analytical technologies, establishing analytical control strategies, and supporting chromatographic method development using Supercritical Fluid Chromatography (SFC). The successful candidate will have a strong foundation in analytical chemistry and organic chemistry, hands‑on laboratory experience, and expertise in chromatographic techniques including SFC,

HPLC/UPLC

, UV, and LC‑MS. This position offers the opportunity to contribute to cutting‑edge pharmaceutical development within a collaborative research environment. Location: Cambridge, MA. Schedule: Standard EST Business Hours. Duration: 6‑month contract. Pay Rate: $31–36/hour. Analytical Method Development Develop, optimize, and troubleshoot analytical methods using Supercritical Fluid Chromatography (SFC). Support analytical control strategy development for small molecule drug substances and drug products. Design and execute experiments under the guidance of the manager. Establish analytical protocols and support method lifecycle activities. Laboratory Testing & Analysis Analyze samples using HPLC, UPLC, and SFC systems coupled with UV and/or mass spectrometry detection. Perform routine laboratory activities and maintain accurate experimental records. Utilize analytical instrumentation and associated software for data acquisition and processing. Data Analysis & Documentation Analyze and interpret analytical data and experimental results. Prepare technical reports, summaries, and scientific documentation. Maintain compliance with Good Documentation Practices (GDP) and laboratory recordkeeping standards. Support data review and reporting activities. Scientific Collaboration Participate in project meetings and scientific discussions. Attend relevant seminars and training sessions related to therapeutic small molecule development. Contribute to a culture of innovation, continuous learning, and scientific excellence. Required Qualifications MS or PhD in Chemistry, Biochemistry, Chemical Engineering, Pharmaceutical Sciences, or a related scientific discipline. Hands‑on experience with HPLC/UHPLC systems and associated software. Direct experience with Supercritical Fluid Chromatography (SFC) is required. Understanding of liquid chromatography (LC) separation principles. Experience working in a laboratory environment. Knowledge of analytical techniques including: HPLC/UPLC SFC UV Detection

LC‑MS

Laboratory skills: proficiency with basic laboratory techniques, including: Pipetting Solution preparation Sample handling Centrifugation Preferred Qualifications Experience with analytical method development in the pharmaceutical industry. Experience supporting drug substance and drug product development programs. Familiarity with regulatory documentation and pharmaceutical development workflows. Desired Skills & Competencies Strong analytical and problem‑solving skills. Scientific curiosity with a willingness to learn new technologies and methodologies. Ability to independently design, execute, and document experiments. Strong data analysis and interpretation capabilities. Excellent written and verbal communication skills. Strong attention to detail and organizational skills. Ability to work effectively in a collaborative research environment. Ideal Candidate Profile The ideal candidate is an MS or PhD‑level scientist with hands‑on experience in chromatographic method development, particularly Supercritical Fluid Chromatography (SFC), within a pharmaceutical, biotechnology, or academic research environment. They possess a strong understanding of analytical chemistry principles, enjoy solving complex scientific challenges, and are eager to contribute to the development of innovative small molecule therapeutics. #J-18808-Ljbffr Hydrogen Group