Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Information System Security Officer (ISSO)

True Zero Technologies, LLC

Information System Security Officer (ISSO)

True Zero Technologies, a veteran-owned small business, was founded on the principle that the purposeful enablement of people and technology in an organization directly ties to the quality of its outcomes. True Zero recognizes that those outcomes begin and end with our people, and that is what we have built a community of like-minded, driven, and passionate individuals and innovators who are aligned in a common goal of delivering top-tier services to our customers. Our culture and commitment have been recognized through numerous accolades, including being named one of the Best Places to Work in 2023 in two categories ("Prosperous and Thriving" ($5MM–$50MM in gross revenue) and "Mid-Atlantic Region" (DC, DE, MD, NC, VA, WV)), and again in 2025 as a Best Places to Work honoree. In addition, True Zero earned coveted spots on the Inc. 5000 list of fastest-growing companies in America in 2022, 2023, and 2025, a testament to our sustained growth driven by our people-first approach and unwavering dedication to excellence.

True Zero is seeking an Information System Security Officer (ISSO) to support cybersecurity governance and Risk Management Framework (RMF) activities for enterprise information systems at the National Institutes of Health (NIH). Working under the direction of the Senior ISSO, this position partners with System Owners, engineers, cybersecurity operations personnel, and Government stakeholders to maintain the security posture and authorization readiness of assigned systems.

The ISSO is responsible for coordinating the day to day execution of RMF activities, maintaining security documentation, supporting continuous monitoring, tracking remediation efforts, and ensuring cybersecurity activities remain aligned with Federal requirements throughout the system lifecycle. This role requires strong organizational skills and the ability to coordinate activities across multiple technical disciplines while serving as a trusted advisor to system stakeholders.

Job Responsibilities
  • Support assigned information systems through all phases of the Risk Management Framework (RMF) lifecycle.
  • Maintain System Security Plans (SSPs), security documentation, and authorization artifacts to accurately reflect the operational environment.
  • Coordinate with System Owners to ensure security requirements are incorporated into system operations and lifecycle activities.
  • Collect, organize, and validate evidence supporting security control implementation and continuous monitoring activities.
  • Track vulnerabilities, POA&Ms, remediation activities, risk acceptance decisions, and corrective actions to ensure timely resolution and accurate documentation.
  • Coordinate with vulnerability management, penetration testing, and incident response teams to ensure cybersecurity findings are incorporated into authorization documentation and continuous monitoring activities.
  • Support annual assessments, Security Control Assessments (SCAs), audits, and authorization reviews by coordinating evidence collection, documentation updates, and stakeholder participation.
  • Monitor system changes to identify potential impacts to authorization status and coordinate required documentation updates.
  • Assist with contingency planning, incident response planning, interconnection security agreements, privacy documentation, and other required cybersecurity artifacts.
  • Prepare recurring authorization status reports, remediation updates, and security summaries for Government stakeholders.
  • Participate in change management, configuration management, governance meetings, and continuous monitoring activities to ensure cybersecurity considerations remain integrated into operational decision making.
  • Coordinate closely with engineering teams to ensure security controls are properly implemented and documented.
  • Support continuous improvement initiatives that strengthen authorization quality, improve documentation accuracy, and enhance operational efficiency.
Job Qualifications
  • Bachelor's degree in Cybersecurity, Information Systems, Information Technology, Computer Science, or a related discipline.
  • Three or more years of experience supporting Federal cybersecurity, RMF, Assessment and Authorization (A&A), or information assurance programs.
  • Working knowledge of NIST SP 800-37, NIST SP 800-53 Rev. 5, FISMA, and Federal cybersecurity requirements.
  • Experience supporting authorization package development and maintenance.
  • Experience coordinating with System Owners, engineers, cybersecurity operations teams, and Government stakeholders.
  • Strong organizational, analytical, and technical writing skills.
  • Excellent communication skills with the ability to coordinate activities across multiple organizations.
Preferred Qualifications:
  • Experience supporting NIH, HHS, or other Federal civilian agencies.
  • Experience using JCAM, eMASS, ServiceNow GRC, Archer, or similar governance platforms.
  • Experience supporting continuous monitoring, vulnerability management, POA&M management, and cybersecurity assessments.
  • Familiarity with cloud environments, Zero Trust initiatives, and enterprise security operations.
  • Experience supporting FISMA reporting, audit preparation, and ongoing authorization programs.
Preferred Certifications:
  • Security+
  • Certified in Governance, Risk and Compliance (CGRC)
  • CAP (Certified Authorization Professional)
  • CISSP
  • CISM

We're actively searching for talented security and technology practitioners who are ready to experience the True Zero difference. As a True Zero team member, you'll enjoy:

  • Competitive salary, paid twice per month
  • Best in class medical coverage
  • 100% of medical premiums covered by True Zero
  • Company wide new business incentive programs
  • Contribution Incentives (i.e. white papers, blog posts, internal webinars, etc.)
  • 3 weeks of PTO starting + 11 Paid Holidays Annually
  • 401k Program with 100% company match on the first 4%
  • Monthly reimbursement of Cell Phone and Home Internet costs
  • Paternity/Maternity Leave
  • Investment in training and certifications to broaden and deepen your technical skills
Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Information System Security Officer (ISSO) in United States vacancy
  • $87.1k - $157.45k

     ...we’ll help you accelerate your professional path.The Leidos Defense Group is seeking qualified candidates for an Information Systems Security Officer (ISSO) position at Langley AFB. This role supports a major Military Intelligence Program aligned with the USAF Air Combat... 
    Suggested
    Full time

    Leidos

    Hampton, VA
    4 days ago
  • $120k - $150k

    OverviewAMERICAN SYSTEMS is seeking an experienced Information Systems Security Officer ISSO to support the cybersecurity compliance and security posture of assigned information systems. This role is responsible for helping maintain system authorizations, supporting RMF... 
    Suggested

    AMERICAN SYSTEMS

    Quantico, VA
    4 days ago
  • $112.92k - $125.28k

     ...a Department of Defense Top Secret security clearance is required at time of hire...  ...requirements for access to classified information. Due to the nature of work performed...  ...this Position As an Information Systems Security Officer (ISSO) for classified systems at General... 
    Suggested
    Flexible hours

    General Dynamics Mission Systems

    Pittsfield, MA
    19 hours ago
  • $170k - $230k

    Information Systems Security Officer (ISSO) Ft. Meade Area, MD · Government/MilitaryClearance Required: TS/SCI with PolygraphFull-Time | Fully Funded | $170K-$230K Secure the Mission. Set the Standard in Cybersecurity.Helm Point Solutions is a woman-owned cybersecurity... 
    Suggested

    Helm Point Solutions

    Annapolis Junction, MD
    3 days ago
  •  ...particular focus on Defense and National Security mission sets. We leverage more than...  ...and motivated individuals with Systems Administration, Software...  ...backgrounds to join our team as an Information System Security Officer (ISSO). You will collaborate with other Palantir... 
    Suggested
    For contractors

    Barbaricum

    Washington, NC
    19 hours ago
  • $120k - $145k

    OverviewAMERICAN SYSTEMS is an employee-owned federal government contractor supporting...  ...strategic solutions in the areas of Information Technology, Test & Evaluation,...  ...ResponsibilitiesServe as the program Information System Security Officer (ISSO) for several tactical information... 
    For contractors

    AMERICAN SYSTEMS

    Middletown, RI
    2 days ago
  • $87.1k - $157.45k

    The Defense Sector at Leidos is looking for an Information System Security Officer (ISSO) to support a fast-paced program with the Air Force Life Cycle Management Center. This role involves supporting the delivery of comprehensive IT and support services to ensure mission... 
    Full time
    Remote work

    Leidos

    Lorton, VA
    2 days ago
  • If you are looking for a career as a Information Systems Security Officer - ISSO and you are interested in designing, improving, and managing projects through the RMF then our Raleigh, NC division of ARA has an exciting opportunity worth considering. Not only will you solve... 
    Full time
    Work experience placement

    Applied Research Associates

    Raleigh, NC
    1 day ago
  • $110k - $140k

    Title:Information System Security Officer (ISSO)Belong. Connect. Grow. with KBR!KBR’s National Security Solutions team provides high-end engineering and advanced technology solutions to our customers in the intelligence and national security communities. In this position... 
    Full time
    Temporary work
    Work experience placement
    Local area
    Relocation package

    KBR

    Washington, WV
    19 hours ago
  • $107.9k - $195.05k

    Job DescriptionInformation Systems Security Officer (ISSO) Leidos - Cyber & Analytics Business Area, Key Management & Analytics Division, Your...  ...Impact.Leidos has an exciting opportunity for an experienced Information Systems Security Officer (ISSO) to join our Cyber &... 
    Full time
    Immediate start
    Remote work

    Leidos

    Laurel, MD
    1 day ago
  • $135k - $185k

    Ashburn, VAComputer World Services - CWS /Full-time /HybridCWS seeks an Information System Security Officer (ISSO) to ensure information systems compliance for the U.S. Customs and Border Protection’s (CBP) Network Operations Center (NOC) contract. The Information System... 
    Full time
    Contract work
    Local area
    Night shift

    Computer World Services (CWS)Corporation

    Ashburn, VA
    19 hours ago
  • $100.22k - $111.18k

     ...Department of Defense Secret security clearance is required at...  ...requirements for access to classified information. Due to the nature of work...  ..., principles, and secure system practices.Apply a strong...  ...Information System Security Officer (ISSO)-type capacity, supporting the... 
    Flexible hours

    General Dynamics Mission Systems

    Huntsville, AL
    1 day ago
  • $100k - $150k

    OverviewLMI is seeking a highly motivated mid-level Information System Security Officer (ISSO) looking for hands-on experience and opportunity for career growth under direction of the Chief Information Security Officer.LMI is a new breed of digital solutions provider dedicated... 
    Full time
    Contract work
    Shift work

    LMI

    Colorado Springs, CO
    19 hours ago
  • $131.3k - $237.35k

    Leidos has a new and exciting opportunity for a Senior Information Systems Security Officer (ISSO) in our Intelligence Sector, Cyber & Analytics Business Area (CABA). Our talented team is at the forefront in Security Engineering, Computer Network Operations (CNO), Mission... 
    Full time
    Contract work
    Immediate start
    Relocation package
    Flexible hours

    Leidos

    Annapolis Junction, MD
    3 days ago
  • $115.4k - $192.3k

    Are you passionate about driving security compliance in complex cloud environments...  ...decisions. By bringing clarity to information, we ultimately help make communities...  ...seeking an experienced Information System Security Officer (ISSO) to lead and maintain the security and... 
    Full time
    For contractors
    Work experience placement
    Local area
    Work from home

    LexisNexis Risk Solutions Group

    Boca Raton, FL
    19 hours ago
  •  ...thought leader for over 20 years and has offices throughout the United States and...  ...by solving our clients’ toughest security challenges. But that’s not who we...  ...difference. We are on the look out for an Information System Security Officer (ISSO) to join our Federal team in... 
    Full time
    Work experience placement
    Local area
    Flexible hours

    Coalfire

    Washington DC
    1 day ago
  • $85.8k - $180.2k

    Job Title: Information Systems Security Officer - ISSOJob Category: Information TechnologyTime Type: Full timeMinimum Clearance Required to Start: TS/SCI...  ...:Join CACI as an Information Systems Security Officer (ISSO) and help support mission‑critical engineering, operations... 
    Contract work
    Work experience placement
    Flexible hours

    CACI International

    Sarasota, FL
    17 hours ago
  • $102.83k - $154k

     ...Range: $102,831.00 - $154,000.00 Security Clearance: TS/SCI Level of...  ...resides with Warfare Systems (WS), a business group within...  ...will doDesigns and implements information assurance and security engineering...  ...information security experience (ISSO, cyber analyst, cyber auditor... 
    Full time
    Work experience placement
    Local area
    Worldwide

    HII Mission Technologies Division

    Springfield, VA
    2 days ago
  • $92.21k - $125.15k

     ...Technology /Full Time On-Site /On-siteISSOEmployment Type: Full-Time, Experienced Department: Information Technology CGS is seeking an Information Systems Security Officer (ISSO) with DIACAP and/or RMF experience who has deep expertise in security assessment... 
    Full time
    Local area

    CONTACT GOVERNMENT SERVICES

    Washington DC
    19 hours ago
  • $130k - $170k

    Title:Information System Security Officer (ISSO)Belong. Connect. Grow. with KBR!KBR’s National Security Solutions team provides high-end engineering and advanced technology solutions to our customers in the intelligence and national security communities. In this position... 
    Full time
    Local area
    Flexible hours

    KBR

    Patuxent River, MD
    19 hours ago
  • $86.8k - $165.2k

     ...Requirements:Active and transferable U.S. government issued security clearance is required prior to start date.​ U.S....  ...and defense.Our cybersecurity team is seeking a Senior Information Systems Security Officer (ISSO) to support our team 100% onsite at our facility in... 
    Temporary work
    Work experience placement
    Work at office
    Remote work
    Relocation package
    Flexible hours

    Raytheon

    Mckinney, TX
    19 hours ago
  • General information Job Posting Title Information System Security Officer (ISSO) Date Thursday, August 20, 2026 City Arlington State VA Country United States Working time Full-time Description & Requirements Maximus is seeking a... 
    Minimum wage
    Full time
    Contract work
    Temporary work
    Work experience placement

    Maximus

    Arlington, VA
    19 hours ago
  • $107.5k - $204.5k

     ...Requirements:Active and transferable U.S. government issued security clearance is required prior to start date.​ U.S....  ...and defense.Our cybersecurity team is seeking a Senior Information Systems Security Officer (ISSO) II to support our team 100% onsite at our facility in... 
    Temporary work
    Work experience placement
    Work at office
    Remote work
    Relocation package
    Flexible hours

    Raytheon

    Mckinney, TX
    19 hours ago
  • $104.4k - $156.6k

    Title:Information Systems Security Officer (ISSO)Belong. Connect. Grow. with KBR!KBR’s National Security Solutions team provides high-end engineering and advanced technology solutions to our customers in the intelligence and national security communities. In this position... 
    Full time
    Temporary work
    Work experience placement
    Local area
    Relocation package
    Flexible hours

    KBR

    Colorado Springs, CO
    3 days ago
  • $68.9k - $131.1k

     ...Requirements:Active and transferable U.S. government issued security clearance is required prior to start date.​ U.S....  ...Aerospace Global Security Services (GSS) is seeking an Information Systems Security Officer (ISSO) Level 2 to support cybersecurity operations for... 
    Temporary work
    Work experience placement
    Work at office
    Remote work
    Flexible hours

    Raytheon

    Cedar Rapids, IA
    19 hours ago
  • $112k - $179k

    Responsibilities Job SummaryWe are seeking a highly skilled and technically proficient Information Systems Security Officer (ISSO) with hands-on experience developing, implementing, and validating security controls within DoD RMF environments. This role requires deep... 
    Contract work
    Shift work

    Peraton Corporation

    Herndon, VA
    19 hours ago
  •  ...Information Systems Security Officer (ISSO) The client is looking for an Information Systems Security Officer (ISSO) to provide support for a program, organization, system, or enclave's information assurance program. Provides support for proposing, coordinating, implementing... 

    Beyond SOF

    Maryland
    4 days ago
  •  ...Position Summary: Maintain the operational security posture for information systems in Special Access Programs (SAPs) supporting DoD agencies. Collaborate...  ...security safeguards for computer systems. Perform ISSO duties for in-house and external customers. Conduct... 
    For contractors

    Macpower Digital Assets Edge

    San Antonio, TX
    3 days ago
  •  ...About the role Seeking a Senior Information System Security Officer (ISSO) to support a critical government contracting program in Annapolis Junction, MD. The ideal candidate will have extensive experience in information systems security, particularly in large software... 

    Falcon IT & Staffing Solutions

    Annapolis, MD
    3 days ago
  •  ...years of directly related ISSO or cybersecurity experience...  ...: Support system authorization, continuous...  ...ensuring adherence to DoD security requirements and risk management...  ...Strong experience as an Information System Security Officer (ISSO) or in a similar cybersecurity... 
    Full time
    Work experience placement

    Macpower Digital Assets Edge

    Huntsville, AL
    19 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Information System Security Officer (ISSO). Be the first to apply!