Director, Translational Science (Neurology)

At Eisai, we aim to satisfy unmet medical needs and enhance the benefits healthcare provides to patients, families, and caregivers. Position Summary The Director of Translational Science is a scientifically driven leader who contributes to and drives the execution of integrated translational strategies across neurology programs spanning discovery through early clinical development. This role focuses on enabling data‑driven decision‑making by linking disease biology, biomarkers, and clinical outcomes. The successful candidate will combine strong scientific insight with hands‑on engagement in biomarker strategy, data interpretation, and cross‑functional collaboration. Key Responsibilities Translational Strategy & Execution Contribute to and drive execution of translational strategies across neurology programs Design and implement multi‑modal biomarker approaches (e.g., biofluid, imaging, digital biomarkers) Help define data‑driven decision frameworks in collaboration with translational and clinical leadership Translate emerging disease biology into testable clinical hypotheses and biomarker strategies Clinical & Scientific Integration Lead translational components of programs from study design through data analysis and interpretation Interpret and contextualize biomarker and clinical data to inform program decisions and development strategy Partner with Clinical, Clinical Pharmacology, and Biostatistics teams to support trial design, dose strategy, and endpoint selection Bridge preclinical findings and clinical development through mechanistic and disease‑relevant insights Biomarker Development & Data Insights Contribute to development and implementation of biomarker strategies supporting clinical trials Work closely with internal teams and external partners to ensure robust biomarker performance and data quality Collaborate with data scientists to integrate datasets and deliver actionable insights from complex, multimodal data Collaboration & Scientific Leadership Serve as a key translational representative on cross‑functional program teams Influence program direction through scientific insight and data‑driven recommendations Act as a scientific thought partner within the team and contribute to capability building Present findings internally and externally; contribute to scientific publications and congress presentations May mentor junior scientists or contribute to development of team expertise Innovation & External Engagement Engage with academic and industry experts to stay at the forefront of emerging science in neurodegenerative diseases Apply innovative approaches (e.g., omics, AI/ML, digital biomarkers) to better understand disease heterogeneity and progression Integrate multimodal data to refine disease models, patient stratification approaches, and biomarker strategies Regulatory Contributions Contribute to translational aspects of regulatory documents and submissions (e.g., protocols, investigator brochures, briefing materials) Partner with senior leaders to support Health Authority interactions and strategy Support development of companion diagnostic and biomarker qualification strategies Qualifications PhD, MD, or equivalent in Neuroscience, Pharmacology, Molecular Biology, or related field ~8–10 years of relevant experience in pharmaceutical/biotechnology drug development Strong expertise in translational science and biomarker development Demonstrated experience supporting translational aspects of clinical programs Hands‑on experience with biomarkers (fluid, imaging, and/or digital) Preferred: Deep expertise in one or more non‑Alzheimer’s neurodegenerative diseases, including Parkinson’s disease, Lewy body dementia, primary tauopathies (e.g., PSP, CBD) Experience with disease‑relevant biomarkers (e.g., α‑synuclein, tau, sleep/circadian measures) strongly preferred Familiarity with clinical endpoints and disease progression in relevant indications Strong ability to interpret complex biological and clinical data and translate into actionable insights Proven ability to collaborate and influence within cross‑functional teams Scientific curiosity, creativity, and a problem‑solving mindset Excellent communication skills and ability to distill complex concepts for diverse audiences Salary Transparency Annual base salary range: $204,300–$268,200. Eligible to participate in Eisai Inc. Annual Incentive Plan and Eisai Inc. Long Term Incentive Plan. Employees are eligible to participate in company benefit programs. Eisai is an equal opportunity employer and is committed to hiring, training, and promoting in all job qualifications without regard to race, color, religion, gender, age, national origin, citizenship status, marital status, sexual orientation, gender identity, disability or veteran status. Eisai prohibits discrimination against persons because of disability, including disabled veterans. #J-18808-Ljbffr Eisai US