Director, Specialty Pharmacy Operations

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. Opportunity and Summary of Position: The Director, Specialty Pharmacy Operations is responsible for directing, monitoring, and enhancing specialty pharmacy (SP) operations within Madrigal’s Market Access and Trade team. The Director manages dispensing operations across the channel to drive continuous improvement in patient access and adherence, while delivering a best-in-class patient and prescriber experience. The Director also collaborates with key internal stakeholders including MPS, Marketing, Data Analytics, Medical Affairs, Finance, Pricing & Contracting, Regulatory, Legal, and the Market Access field team to identify patient access opportunities and implement impactful solutions. Additionally, the Director engages external stakeholders (e.g. SP’s and IDN’s) in day-to-day program operations and analysis of key data and KPI’s to ensure contractual obligations are meeting/exceeding obligations. This role will have up to three direct reports supporting specialty pharmacy operations, and reports to the Executive Director, Trade and Specialty Distribution Position Responsibilities: Acquire and maintain deep understanding of NASH disease state, resmetirom clinical data and commercialization strategy Build, grow, and lead a team of specialty pharmacy operations specialists Develop and implement the operational structure to support Madrigal’s specialty pharmacy network strategy; closely monitor SP performance to ensure contractual obligations are meeting / exceeding obligations Implement specialty pharmacy program services, enhancements, and operational efficiencies with the goal of positively impacting patient access, adherence, awareness, and affordability Maintain detail-oriented SP program correspondence, call guides, and collateral via internal legal and regulatory approval processes Partner with internal Patient Access and Data Analytics teams to continuously evaluate and analyze specialty pharmacy vendor performance relative to goals and objectives Support Quarterly Business Reviews (QBR’s) and other meetings with SP’s; prepare all materials, communicate expectations to SP’s, and continuously drive performance while identifying key insights to incorporate into strategic planning efforts Collaborate closely with Consumer Marketing and MPS teams to enhance SP program and continuously exceed the needs of HCP’s and patients Oversee brand planning initiatives, operational plans, project budgets, expenses, and timelines Ensure timely and accurate reporting of Adverse Events received through SP network; liaison with Pharmacovigilence and Medical Information teams on all escalations Create and maintain necessary policies, procedures, and business rules for all distribution and dispensing programs Consistently deliver measurable business outcomes based on program-level key performance indicators (KPIs) and provide focused customer-level reporting to leadership Consistently deliver outcomes with enterprise wide impact, tackle projects with increased complexity, and influence change management to operations function across internal teams Ensure the highest level of ethics, quality, and compliance by demonstrating in depth knowledge of laws that govern market access and channel activities Conducts all activities in compliance with all applicable federal, state and local laws and regulations and company policies Qualifications and Skills Bachelor’s degree required; advanced degree in Business or Pharmacy preferred 12-15+ years of related experience in the biopharma industry with a proven, consistent history of high performance in a broad range of leadership roles of increasing responsibilities 7 - 10 years of healthcare industry customer/vendor management experience strongly preferred 5+ years of experience operationalizing specialty pharmacy programs and networks required Experience with specialty distribution operations preferred Ability to develop insights from data trends to improve program performance Experience with pre-launch drugs and new product launches preferred Ability to work effectively within a cross-functional team and in an environment of rapid change Excellent written, organizational, verbal, presentation, and communication skills a must Proficient in MS Office products including PowerPoint, Word, and Excel Travel (approximately 20%) Madrigal offers a competitive Total Rewards strategy to attract and retain top talent and is inclusive of base pay, bonus, equity, and a generous benefits package. Full-time employees are eligible for base salary, bonus, equity, and a comprehensive benefits suite. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs, and market demands. As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $223,000 - $273,000 per year. We comply with all applicable minimum wage laws. All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact View email address on click.appcast.io. Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process. Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to View email address on click.appcast.io. Join our growing team focused on transforming the treatment of people with liver diseases. Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.