Associate Director, Clinical Pharmacology

Overview The Associate Director in Clinical Pharmacology position will support a rapidly expanding clinical portfolio of promising RNAi therapeutics. The candidate in this position should be well versed in clinical pharmacology, PK and PD with strong ability to critically evaluate and interpret data and conduct data analysis. In this role, the candidate is expected to have a strong critical thinking ability with good oral and written communication skills as well as worked independently in a highly matrixed environment. Responsibilities Represent independently Clinical Pharmacology and provide clinical pharmacology support and guidance to clinical stage project teams. Lead the analysis, interpretation, integration and reporting of clinical pharmacology data Conduct PK and PK/PD analyses to guide clinical development decisions Provide clinical pharmacology input for regulatory submissions such as briefing documents, IND, CTA and NDA Prepare and input independently appropriate documents or sections of clinical protocols, Investigator Brochures, Clinical Study Reports with respect to Clinical Pharmacology studies or data Closely partner with Research, Bioanalytical, Clinical, Regulatory, Project Management, and other R&D functions Preparation of abstracts and manuscripts for publications Network with external expert consultants, CRO partners and academic sites to problem solve and develop scientific solutions to clinical pharmacology issues Qualifications Ph.D. (or Pharm.D.) in a relevant field (i.e. Pharmacokinetics, Pharmacometrics, Clinical Pharmacology) with at least 5 years’ experience in pharmaceutical/biotech industry In depth knowledge of clinical pharmacology, pharmacokinetics, modeling and simulation, PK/PD principles, ADME and clinical data interpretation In depth knowledge of international guidelines related to Clinical Pharmacology and Pharmacometrics Proficient in using Phoenix WinNonlin, R, NONMEM, or other pharmacokinetic, modeling and data visualizations software. Ability to function in a highly matrixed team environment is essential Ability to work independently Strong communication and presentation skills (verbal and written) Excellent interpersonal skills and ability to work independently Fluency in English (verbal and written) U.S. Pay Range $175,800.00 - $237,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k) with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer. #J-18808-Ljbffr