Scientist III, Bioinformatics

Work Schedule Standard (Mon-Fri) Environmental Conditions Office Job Description Support primer design and the development of targeted sequencing panels, building pipelines and algorithms for next-generation sequencing within our Bioinformatics R&D team in the Clinical Next Generation Sequencing Division. Location This is a fully onsite role based in Carlsbad, CA or South San Francisco, CA. A Day in the Life Design assays for custom targeted sequencing panels for external and internal researchers Understand key scientific questions and translate them into effective assay design strategies Partner with external customers to understand project requirements and deliver high-quality design solutions that meet their needs Collaborate cross-functionally with molecular biologists, product management, and other bioinformatics and software team members to support new product development, launch, troubleshooting, and optimization Develop, maintain, and operate bioinformatics pipelines for assay design, data mining and analysis Improve assay designs through iterative analysis of sequencing data and development of heuristics, optimization methods, and algorithms Evaluate, implement, and scale new technologies and methods to optimize and automate pipelines for primer design Education PhD in bioinformatics, statistics, genomics, computational biology, computer science or related field; or MS with 3+ years of relevant industry experience Experience Proficiency in Python and shell scripting Hands‑on experience with bioinformatics production systems Experience with targeted NGS sequencing, Ampliseq technology or PCR primer design is highly preferred Experience with sequence analysis tools (BLAST, MAFFT/Clustal, Bowtie/BWA, samtools/bedtools) and strong understanding of genomic databases and annotations (GenBank/RefSeq, ENSEMBL, UCSC) Working knowledge of statistical modeling, optimization, or machine learning applied to genomic or assay‑design data Experience applying modeling or machine learning approaches to support assay performance prediction, off‑target assessment, QC flagging, or design‑rule optimization is preferred Knowledge, Skills, Abilities Excellent communication and organizational skills Self‑motivated, collaborative, and detail‑oriented Strong problem‑solving and troubleshooting skills Commitment to delivering high‑quality results with integrity and professionalism Other Must be legally authorized to work in the United States without sponsorship now or in the future Must be able to pass a comprehensive background check and drug screen Compensation and Benefits The salary range estimated for this position based in California is $95,900.00–$127,800.00. A choice of national medical and dental plans, and a national vision plan, including health incentive programs Employee assistance and family support programs, including commuter benefits and tuition reimbursement At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short‑and long‑term disability in accordance with company policy Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount For more information on our benefits, please visit: #J-18808-Ljbffr