Senior Director, US Rare Disease Value and Access
BioSpace
Job title: Senior Director, US Rare Disease Value and Access Location: Cambridge, MA About The Job Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, youll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. As Senior Director, US Rare Disease Value and Access within our US Rare Disease Leadership Team, you'll own payer-focused access strategy across a $2.2B business with 7 marketed products and 2 pipeline launches, including a landmark AATD therapy in 1H 2027. You'll lead pricing, contracting, reimbursement, and GTN strategy to maximize formulary adoption and patient access. This role is a member of the US Leadership Team and reports directly to the General Manager. Ready to get started? You’ll be joining Sanofi's US Rare Disease business at a pivotal moment managing market access for a portfolio with clear growth trajectory to $3.1B by 2030, leading payer strategy for breakthrough therapies, and ensuring patients can access innovative treatments without delay. About Sanofi We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives. Main Responsibilities Partner with GM and senior leadership to set direction for pricing, contracting, GTN, and reimbursement across rare disease portfolio Develop evidence-based market access strategies that maximize formulary adoption and patient access Create compelling value propositions for payers, providers, and key stakeholders Oversee and optimize GTN across the therapeutic areapricing, rebates, and discounts by channel Monitor GTN performance and deliver recommendations to senior leadership to protect profitability Collaborate with Finance, Forecasting, Trade, Legal, and Patient Support Services to improve net sales Lead GTN pull-through across all channels and geographies based on formulary position Anticipate changes in regulatory and reimbursement landscape; ensure sustained compliance and access Develop primary payer research and advisory board programs to close market access knowledge gaps Champion launch readiness for landmark AATD therapy (1H 2027) across payer, access, and reimbursement dimensions Monitor competitive landscape and payer behavior in partnership with Business Insights & Solutions Define KPIs and track progress against access and financial targets Balance brand objectives and patient access priorities when they are in conflict Build, develop, and lead a high-performing team of 2 direct reports About You Role Overview: The Senior Director, US Rare Disease Value and Access owns the value, evidence, pricing, and reimbursement strategy that turns an approved rare disease therapy into a covered, affordable, accessible one. The role spans HEOR and evidence generation, pricing and contracting, payer engagement, and policy working backwards from what payers need to be convinced of value, often with limited trial data. In rare disease, access is not a downstream function: it is a strategic driver that shapes the commercial case from before launch. Beyond access expertise, the Head of Access Strategy must lead the function through the new era of AI-augmented evidence and value work. The six behaviors below apply to the whole leadership team; the ones this role leans on hardest are highlighted. Leadership Behavior What It Means in the New Era Leads with AI-augmented judgment Uses data and AI to decide faster and better while owning the judgment calls AI cannot make. Orchestrates across boundaries Delivers through influence, shared goals, and trust as functional silos dissolve not through positional control. Drives change and adoption Pulls the team through AI and digital change, creates psychological safety to experiment, and names resistance rather than tolerating it. Obsesses over the patient outcome Anchors decisions to the patient's find-to-adherence journey, not functional activity metrics; treats advocacy and equity as strategic. Models learning agility Reskills continuously, experiments, and fails fast in the open so the team does the same. Builds talent density Runs lean with an elite bar: a few exceptional people, amplified by AI, outproduce larger teams. Makes the hard talent calls, raises the standard, and develops those they keep. Qualifications Bachelor's degree required; advanced degree (MBA, PharmD, MPH, MS, PhD) strongly preferred 10+ years of market access and payer experience, gained within the pharmaceutical/biotech industry or from external environments such as payer organizations, managed care, consulting, or health economics firms 7+ years of leadership experience managing teams and cross-functional initiatives Demonstrated expertise in payer access strategy: pricing, contracting, reimbursement, formulary management Proven track record in GTN management and financial modeling Strong financial acumen including P&L impact and pricing strategy Experience with value proposition development and payer evidence generation Experience in rare disease or specialty therapeutics preferred Excellent communication, negotiation, and executive influence skills Ability to navigate complex, highly regulated environments while managing multiple priorities Why choose us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave. Lead market access strategy for a high-growth $2.2B rare disease business with clear path to $3.1 Play a pivotal role in launching a landmark AATD therapy that will transform patient lives Join the US Leadership Team and shape payer strategy across the entire rare disease portfolio Drive formulary adoption and reimbursement for breakthrough therapies with cutting-edge HEOR, RWE, and payer evidence strategies Be part of a mission-driven team chasing the miracles of science to improve patients' lives. Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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#vhd All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here. #J-18808-Ljbffr BioSpace- Sanofi is seeking a Senior Director, US Rare Disease Value and Access in Cambridge, MA to lead payer-focused access strategy for a multi-billion portfolio, including pricing, contracting, reimbursement, and GTN. You will partner with senior leadership to maximize patient...Senior
$167k - $270k
...NoDepartment: HC-NA-RCUMA2A US MarketingRecruiter:... ...of patients with rare tumors. We developed and... ...importance of our work. We value authenticity because... ...for.Your Role:The Director, Value, Access & Pricing (VAP) GOMEKLI... ...experience required in rare disease or Oncology5+ years in...SuggestedTemporary workWork at officeLocal areaImmediate startRemote work3 days per week$150.7k - $226k
...lives of patients with rare tumors. We... ...importance of our work. We value authenticity because diverse... ...can only help us find the answers that... ...Role: The Associate Director, Payer & Access Marketing- US Rare Tumors... ...Oncology and/or rare disease experience Ability...SuggestedLocal area3 days per week$235k - $330k
...deploying TPD to address disease targets and pathways inaccessible... ..., please visit or follow us on X (formerly Twitter) or... ...medicines.COLLABORATE: We value trust + transparency from... ...you’ll make an impact:The Senior Director, Outcomes, Value & Access will serve as Kymera’s...Senior- ...This is what drives us as we research,... ...individuals united by strong values, each bringing... .... Chiesi Global Rare DiseasesChiesi Global Rare Diseases is a Chiesi Group’s... ...what you will doThe Senior Director, RWE is accountable... ...regulatory, medical, market access, and commercial...SeniorHourly payWork at officeLocal areaRemote workRelocation packageFlexible hours
$151.08k - $226.62k
...will do: The Associate Director, US HCP Peer-to-Peer (P2P) Marketing, gMG & NMOSD, Rare Neurology, is a member of the... ..., Compliance, and Market Access to ensure compliant, high-quality... ...HCP engagement ~ Rare disease / Specialty / high-value biologics experience ~...Temporary workWork at officeNight shift- ...muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a... ...Summary of Position: The Senior Manager / Associate Director, HCP Marketing (US) will play a key role in the... ...with Medical Affairs, Market Access, Patient Services, Regulatory,...Senior
$231.99k - $347.98k
...Position : Senior Director, Head of Rare Neurology Thought Leader Liaisons Location : Boston, MA (US Headquarters for Alexion) Hybrid: 3... ...of people living with rare diseases. We lead with breakthrough... ...culture where people feel valued, connected, and empowered....SeniorTemporary workLocal areaNight shift3 days per week$210k - $300k
...patients living with rare neuroendocrine diseases. We develop... ...Their courage inspires us to challenge convention... ...Rhythm is seeking a Senior Director, Biostatistics to join... ...passionate about expanding access to reach more... ...At Rhythm our core values are: We are committed...SeniorInterim roleWork at officeFlexible hoursShift work$252k - $378k
...Job DescriptionGeneral Summary:The Senior Director (non-MD) serves as a US Medical Affairs asset lead responsible... ...with Commercial, Market Access, HEOR, Regulatory, Clinical Development... ...experience in nephrology, immunology, or rare disease strongly preferred.Experience...SeniorFull timeSummer workRemote workFlexible hoursShift work2 days per week$269k - $291.67k
...new era for treating diseases with high unmet needs.... ...our people. Our core values - be audacious, be curious... ...The Opportunity The Senior Director Toxicology will support... ...delivery approach, rare disease development, endocrine... .... You must have access to work in a setting...SeniorLocal areaRemote work$206.25k - $297.92k
Job title: Senior Director, Global HEVA Neurology, Early... ...mission drives us to pursue... ...’s identity. When disease disrupts self-identity... ...patient care and access. As HEOR experts,... ...evidence to demonstrate value and drive access to... ...challenges, rare diseases, cancers,...SeniorFull timeWork at officeWorldwide- Ipsen is seeking a Director, Epidemiology and RWE Sciences in Cambridge, MA. This role leads the global evidence strategy for Rare Diseases, overseeing real-world evidence generation for various products. The ideal candidate will have over 8 years of experience in epidemiology...
- Ipsen Biopharmaceuticals Inc. is seeking a Director of Key Opinion Leader Marketing in Rare Disease to shape external expert engagement and education. You will define strategy, govern speaker programs, and drive adoption through peer-to-peer initiatives with KOLs, advocates...
$185.8k - $278.6k
Work Your Magic with us! Start your next chapter and... ...specialist focusing in rare tumor, you'll generate rigorous... ...strategy and inform access decisions by population... ...comprehensive value evidence strategies — design... ...standardsCharacterizing disease burden and real-world outcomes...Flexible hours$184.62k - $239.7k
...You’ll find that rare opportunity at PharmaEssentia... .... Join us, and let’s... ...for challenging diseases in the areas of hematology... ...Overview: The Director, Patient Access will serve as the... ...mitigation plans to senior leadership and... ...employees. As a valued member of PharmaEssentia...Flexible hours$190k - $240k
..., Eastern Territory US Reporting to : Senior Director, Medical Affairs – Americas... ...of patients with rare disorders through... ...a therapeutic and disease area scientific expert... ...-balanced and high-value exchange of clinical... ...collaboration with Market Access, Government Affairs,...SeniorLocal areaRemote workNight shift$162k - $270k
...Required:NoneWhat You Will Do:The Value & Access team provides... ...This will involve working with senior staff to develop project proposals... ...client relationships. Associate Directors oversee multiple projects simultaneously... ...fee.SummaryLocation: US - NY, New York; US - Remote (...Full timeWork experience placementWork at officeRemote workFlexible hours- ...Job Title:** Associate Director, Medical Value and Outcomes (Mid-... ...scientific exchange on disease state management and the... ...with immune challenges, rare diseases and blood... ...education and provides access to medical, health policy... ...-functionally with US Market Access (USMA) Account...Temporary workLocal areaRemote work
- ...Join to apply for the Senior Director, Biostatistics role at BioSpace 22... ...severe and life-threatening diseases. Why Join Intellia? Our mission... ...science, we live our four core values: One, Explore, Disrupt,... ...that patients are counting on us to make the promise a reality...SeniorFull timeLocal areaRemote work
- ...their growth. As a Commerce Senior Director, you will establish and lead... ...and Family Support : Access fertility benefits for all team... ...and expectations. What Sets Us Apart Being part of PMG means... ...and clients, delivering value, results, and innovation—which...SeniorLocal area
- ...This is what drives us as we research, develop... ...united by strong values, each bringing unique... .... Chiesi Global Rare DiseasesChiesi Global Rare Diseases is a Chiesi Group’s... ...Strategic Insights, the Senior Manager, HIDO Global... ...friendly environment with access to resources and...SeniorHourly payLocal areaRemote workRelocation packageFlexible hours
- ...on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities. BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried...SeniorHourly payRemote workWorldwide
- Ipsen Biopharmaceuticals Inc. in Cambridge, MA seeks an Associate Director of HCP Marketing for the Bylvay brand to drive U.S. rare disease marketing initiatives and support the ongoing launch in PFIC and Alagille syndrome. The role focuses on multichannel engagement, advisory...Senior
$211.66k - $317.48k
...Job Title: Senior Director US Head of Country Operations, Study Start-up... ...a country-level post-trial access plan is established and that... ...clinical trial environment, rare disease landscape, global regulatory... ...improve performance and create value. Strong portfolio and project...SeniorHourly payTemporary workWork at officeLocal area3 days per week$183k - $252k
...Role The Nephrology Associate Medical Director role is a part of US Medical Affairs, a strategic partner... ..., Commercial, Market Access). Collaborate with global, regional... ...find therapies for neurological and rare diseases is a unique focus within our industry...Temporary workLocal area$188.6k - $283k
Work Your Magic with us! Start your next chapter and join EMD... ...work in the US. Your Role:The Senior Counsel, Rare Tumors will provide... ...compliance, and patient-centered values.Pay Range for this position:... ...We are committed to creating access and opportunities for all to...SeniorFlexible hours$206.25k - $343.75k
Job title: US Senior Medical Director, Rare HematologyLocation: Cambridge, MA / Morristown, NJAbout the jobJoin... ...people with immune challenges, rare diseases, cancers, and neurological... ...the rare hematology portfolioPayer & Access SupportSupport the Managed Markets group...SeniorFull time$225k - $275k
...life-threatening diseases. Beyond our science... ...our four core values: One, Explore, Disrupt... ...are counting on us to make the... ...together. About You:The Director of Patient Access Liaisons is a... ...closely with the Senior Director and cross... ....Experience in rare disease and/or HAE...Full time$232k - $348k
...for Cystic Fibrosis (CF), sickle cell disease, beta-thalassemia, and moderate to... ...diabetes.Vertex is seeking an experienced Senior Director, US Market Access Strategy to lead market access... ...indicationsOversee development of the POVE value proposition in partnership with...SeniorFull timeContract workSummer workRemote workRelocationFlexible hours2 days per week3 days per week
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