Global Trials Optimization Specialist / Project Manager I (Sponsor Dedicated/Remote - US only)

Global Trials Optimization Specialist / Project Manager I (Sponsor Dedicated/Remote - US only)

Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.

Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.

Discover what your 25,000 future colleagues already know:

Why Syneos Health
• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life. 
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress. 

Job Responsibilities

Global Trials Optimization Specialist

Sponsor Dedicated/ Remote - US only

Are you energized by using data, planning, and cross-functional collaboration to help clinical trials enroll successfully? We’re seeking a Global Trials Optimization Specialist to support program feasibility, recruitment and retention planning, and in-life trial optimization across global clinical studies.

In this role, you’ll help translate trial goals, country input, modeling data, and enrollment insights into practical strategies that support study execution. You’ll partner with clinical trial teams, vendors, legal, analytics, and other stakeholders to identify enrollment opportunities, address challenges, and support patient- and site-facing recruitment efforts.

This is an excellent opportunity for someone who enjoys combining clinical trial operations, feasibility strategy, recruitment planning, stakeholder coordination, and performance analysis to help studies reach the right participants.

What You’ll Do

Program Feasibility and Trial Optimization

• Gather data, benchmarks, and modeling inputs to support feasibility and trial optimization planning.

• Support program review development, including content review and escalation of requirements as needed.

• Plan timelines for validation, deliverable development, stakeholder alignment, presentation preparation, and country validation requests.

• Support validation and Clinical Trials Allocation Committee activities, including scenario planning, risk table inputs, validation review, modeling updates, and final allocation requests.

• Author the initial Global Trials Optimization Report and maintain subsequent report updates throughout the trial lifecycle.

• Complete recruitment needs assessments and ensure trial-level GTO reports remain current and actionable.

Recruitment and Retention Planning

• Lead early recruitment and retention planning during feasibility, including inputs for project cost estimates.

• Develop initial recruitment needs assessments and, where applicable, program-level recruitment budget estimates.

• Submit vendor requests and prepare recruitment and retention plans.

• Partner with legal on concept reviews, vendor proposal reviews, scope of work finalization, and material or tactic reviews.

• Ensure recruitment and retention plans, including enrollment support materials, are implemented effectively.

• Oversee enrollment support material development and tactic execution.

• Provide required materials to the Metrics, Analytics & Performance team to support accurate Study Optimizer plan entry.

• Request and manage appropriate system updates as trial needs evolve.

In-Life Trial Management

• Partner with study teams to identify enrollment challenges, assess risks, and recommend potential mitigations.

• Manage routine enrollment support materials and vendor activities.

• Monitor enrollment performance and prepare standard reporting.

• Analyze performance trends and identify opportunities for enhanced support.

• Coordinate enhanced enrollment support activities, which may include:

  • Rescue site and country activities

  • Internal recruitment and retention refresher meetings

  • External recruitment and retention booster meetings

  • Additional participant- or site-facing materials

  • Rescue vendor engagement

  • Advocacy engagement and community outreach

What You’ll Bring

Required Qualifications

• Experience supporting clinical trials, feasibility, recruitment planning, enrollment strategy, or trial optimization.

• Strong ability to gather, interpret, and apply data to support planning and decision-making.

• Experience coordinating timelines, deliverables, stakeholder reviews, and cross-functional inputs.

• Ability to work with clinical trial teams, vendors, legal, analytics, and other business partners.

• Strong written communication skills, including the ability to develop clear reports, plans, updates, and study-facing materials.

• Detail-oriented approach with the ability to manage multiple priorities in a fast-paced clinical research environment.

Highly Preferred Qualifications

• Oncology clinical trial experience, especially in lung or breast cancer studies .

• Prior experience as an oncology site coordinator .

• Experience with recruitment and retention vendors, enrollment support materials, or patient/site-facing recruitment tactics.

• Familiarity with enrollment monitoring, performance analysis, country validation, risk tables, or trial allocation processes.

Why This Role Matters

Successful clinical trials depend on reaching the right participants, supporting sites effectively, and responding quickly when enrollment challenges arise. As a Global Trials Optimization Specialist, your work will directly support smarter planning, stronger recruitment strategies, and more effective trial execution.

You’ll have the opportunity to influence global study planning, collaborate with experienced clinical research partners, and help improve how trials connect with patients and sites.

Candidate Profile

We’re especially interested in candidates with oncology trial experience and a strong understanding of site operations, enrollment strategy, and recruitment/retention planning. Internal candidates will be prioritized initially; external candidates may be considered after the initial internal review period.

If you’re a clinical research professional who enjoys bringing structure, insight, and strategy to trial enrollment planning, we’d like to hear from you. Apply today to help support meaningful clinical trials through thoughtful feasibility, recruitment, and optimization work.

Salary range for this role is $95,000–$105,000

At  Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time.  Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:

$80,600.00 - $145,000.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive.  The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description.  The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above.   Further, nothing contained herein should be construed to create an employment contract.  Occasionally, required skills/experiences for jobs are expressed in brief terms.  Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees.  The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

Summary

Under the direction of a Project Manager Lead supports overall project management of clinical studies by helping control the scope, schedule and cost of assigned project(s), which may range from single service studies to full scope or multiple protocol projects. Duties may include liaising with Customers, vendors and/or investigative sites to manage projects from proposal development to final deliverables to the customer. Upon displaying proficiency, a Project Manager (PM I) may be awarded the opportunity to function at the Project Manager II (PM II) level within a large project team or on a small project which offers continued mentorship.