Senior Scientist, Translational Immunology

The Role Moderna is seeking a Senior Scientist to join the Infectious Disease Research Immunology team in Cambridge, MA. You will lead translational immunology studies that help teams understand immune responses and make decisions about vaccine and therapeutic candidates. The role combines scientific leadership with experimental expertise across preclinical models and human samples. As a member of the Immunology leadership team, you will work across programs to identify the questions that matter, develop study plans, and interpret results in their biological and clinical context. We are seeking an immunologist with deep expertise in B cells, T cells, or innate immune cells who can apply that expertise to new questions and learn beyond their original specialty. The scientific focus will reflect your strengths and the needs of the portfolio. Expertise in every area listed below is not expected. Here’s What You’ll Do Lead translational immunology strategy for assigned programs, identifying the immune mechanisms to investigate and the evidence needed to inform candidate selection, study design, and subsequent development decisions. Design and lead studies using human samples and preclinical models to characterize immune‑cell responses and connect cellular, antibody, and functional findings to program questions. Provide experimental expertise and scientific oversight in your area of specialization. Develop fit‑for‑purpose assays, establish appropriate controls, and explain what the results do and do not support. Work with colleagues in virology, bacteriology, antigen design, clinical development, medical affairs, biomarkers, and computational sciences to integrate findings across studies and guide the next experiments. Lead studies in your area of immunology expertise, such as B‑cell and antibody biology, T‑cell responses, or innate immunity, while applying and expanding your skills to address questions across programs. Support platform studies and new discovery efforts by evaluating emerging methods and identifying approaches that can be used across programs. Set scientific priorities with program teams, balance competing demands, and communicate scientific rationale, uncertainties, and recommendations clearly to research and development leaders. Mentor scientists and research associates, strengthen experimental design and data interpretation, and help colleagues build new capabilities. Here’s What You’ll Need (Basic Qualifications) PhD in immunology or a related discipline, with a strong foundation in immune‑cell biology and relevant research experience. 2+ years of experience. Deep expertise in at least one area of cellular immunology, such as B‑cell, T‑cell, or innate immune‑cell biology, supported by hands‑on experience studying primary immune cells. Experience designing and interpreting cellular assays, including multiparameter flow cytometry and functional assays appropriate to your area of expertise. Demonstrated ability to translate a biological or clinical question into a study plan and use the findings to guide a research or development decision. Experience leading scientific work across disciplines, mentoring colleagues, and communicating complex results and their limitations clearly. Ability to learn new biological areas and methods quickly, adapt to changing program needs, and contribute beyond your primary specialty. Here’s What You’ll Bring to the Table (Preferred Qualifications) B‑cell and antibody biology, including antigen‑specific cell isolation, antibody discovery, repertoire analysis, epitope mapping, or antibody binding and function. T‑cell biology, including antigen‑specific responses, differentiation and memory, antigen presentation, or functional assessment. Innate immune‑cell biology, including myeloid‑cell function, immune activation, or mechanisms that shape vaccine responses. Mucosal or tissue immunity, including local immune responses and relevant human or preclinical models. Single‑cell or other high‑dimensional immune profiling, with experience integrating cellular, molecular, and functional data. Infectious disease, vaccine, or therapeutic development experience, including translational studies using human samples. Our Working Model As we build our company, we have always believed that an in‑person culture is critical to our success. This role is 100% onsite, reflecting the importance of being physically present to support the work, collaborate closely with colleagues, and contribute to our site‑based operations. Working onsite enables real‑time collaboration, strong team connections, direct mentorship, and the hands‑on partnership needed to deliver our mission. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke‑free, alcohol‑free, and drug‑free work environment. Pay & Benefits At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well‑being resources are designed to support you—at work, at home, and everywhere in between. Competitive healthcare, plus voluntary benefit programs to support your unique needs A holistic approach to well‑being, with access to fitness, mindfulness, and mental health support Family planning benefits, including fertility, adoption, and surrogacy support Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year‑end shutdown Savings and investments to help you plan for the future Location‑specific perks and extras The salary range for this role is $130,800.00 - $209,400.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance. About Moderna Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world‑class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Equal Opportunities Moderna is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accommodations We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at View email address on click.appcast.io. Please inform the company's personnel representative by calling View phone number on click.appcast.io or emailing View email address on click.appcast.io if you need assistance completing any forms or to otherwise participate in the application process. Reasonable Accommodation Notice Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Applicants with disabilities may be entitled to reasonable accommodation under the terms of the Americans with Disabilities Act and certain state or local laws. Please inform the company's personnel representative by calling View phone number on click.appcast.io or emailing View email address on click.appcast.io if you need assistance completing any forms or to otherwise participate in the application process. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. Our Mission and Vision At Moderna we are pioneering the development of a new class of drugs made of messenger RNA (mRNA). This novel drug platform builds on the discovery that modified mRNA can direct the body’s cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs that can have therapeutic activity inside and outside of cells. We have a clear mission to propel the field of mRNA science forward and deliver new medicines to patients and a unique vision for how to achieve this mission. Our Mission: To deliver on the promise of transformative messenger RNA (mRNA) science to bring new medicines to patients. Our Vision: To unlock the potential of mRNA by establishing an ecosystem of teams and partners that will work together to develop the broadest possible array of drugs, across diverse therapeutic areas and routes of administration, for serious diseases that are not treatable today. #J-18808-Ljbffr Moderna Therapeutics