IT Operations Lead
$130k - $135kONI
IT Operations Lead
Own the day-to-day delivery and continuous improvement of ONI's internal IT environment across our sites in the USA and UK, as well as supporting employees in other locations. Serve as the senior hands-on technical lead for IT operations, working closely with ONI's outsourced IT support provider while taking ownership of core systems, infrastructure, security, access, service quality, and IT projects. This role is expected to operate independently, act as the internal escalation point for complex issues, identify risks and opportunities for improvement, and take ownership of practical solutions that strengthen ONI's day-to-day IT operations.
Responsibilities:
Global IT Support and Service Provider Management:
- Ensure employees primarily in the USA and UK, and employees in other locations as required, receive responsive and effective IT support through ONI's outsourced IT support provider.
- Act as ONI's senior internal escalation point for complex, sensitive, or business critical hardware, software, identity, access, and network issues that require deeper knowledge of ONI's systems or business needs.
- Manage the day-to-day relationship with ONI's outsourced IT support provider, including service quality, escalations, ticket trends, prioritization, documentation, and timely resolution of incidents and requests.
- Provide hands on technical support to executives and other business critical users when appropriate, particularly for escalated or complex issues.
Systems and Infrastructure Administration:
- Proactively administer, maintain, and improve ONI's core IT systems and infrastructure, including endpoints, identity platforms, networks, collaboration tools, and office technology.
- Monitor system health, capacity, reliability, and security, and address issues before they materially affect business operations.
- Own technical administration of ONI's Microsoft environment, including Microsoft 365 and Microsoft Entra ID, together with SSO, endpoint management, device management, and related business systems as applicable.
- Maintain video conferencing and office connectivity solutions across ONI locations.
Security, Access, and Compliance:
- Administer user identities, privileged accounts, SSO, and access controls using the principle of least privilege.
- Partner with internal stakeholders and external providers on information security reviews, remediation actions, and security improvement initiatives.
- Support ONI's compliance obligations and security frameworks, including GDPR, Cyber Essentials, ISO 27001, or other applicable requirements.
- Manage and support access to company facilities where IT systems are involved, helping protect the physical security of the business.
IT Projects and Continuous Improvement:
- Lead the technical delivery of IT projects from requirements and solution evaluation through implementation, documentation, and handover.
- Identify opportunities for automation, standardization, and process improvement that increase reliability, security, efficiency, and user experience.
- Evaluate new software and hardware solutions, provide technical recommendations, and coordinate implementation with relevant stakeholders and vendors.
- Use scripting and automation where appropriate to reduce repetitive administration and improve control.
Business Continuity and Operational Resilience:
- Maintain practical backup, recovery, and continuity procedures for critical IT services and ensure they are tested and kept current.
- Identify material IT operational risks and escalate them to the CFO with clear recommendations and options.
- Coordinate response to significant IT incidents and ensure lessons learned are documented and acted upon.
Hardware, Software, and Vendor Management:
- Own the lifecycle of company hardware and software assets, including procurement, deployment, inventory, maintenance, wipe, rebuild, reissue, and retirement.
- Maintain accurate records of IT stock, assignments, licenses, renewals, and key vendor information.
- Own the operational relationship with ONI's outsourced IT support provider and work with security, telecommunications, software, and other technology vendors to resolve issues, manage escalations, and deliver services effectively.
Employee Onboarding and Offboarding:
- Own the IT account lifecycle for starters, movers, and leavers, including account creation, access assignment, device preparation, changes, and deactivation.
- Provide IT onboarding and systems training to new employees.
- Collaborate with HR and Logistics to ensure equipment is provided and returned promptly for local and remote employees.
Documentation and Knowledge Management:
- Maintain accurate technical documentation covering systems, configurations, procedures, support resolutions, vendors, and system changes.
- Create and maintain user guides and knowledge base content that improve employee self-service and reduce repeat support issues.
- Ensure critical IT knowledge is documented so that key systems do not depend on a single individual.
Required Experience & Skills:
- At least 8 years of progressive professional experience in internal IT, IT operations, infrastructure, systems administration, or end user support, ideally within a small or medium sized organization.
- Operating as a senior technical escalation point and independently owning complex IT issues through resolution.
- Hands on administration of identity, endpoint, collaboration, and access platforms in a mixed Windows, MacOS, and iOS environment.
- Device lifecycle management, including procurement, deployment, wipe, rebuild, reissue, inventory, and retirement.
- Employee onboarding and offboarding, including account and access lifecycle management.
- Implementation or significant upgrade of new software, hardware, infrastructure, or security systems.
- Working with outsourced IT support or managed service providers, including managing escalations, service quality, ticket trends, and accountability for resolution.
- Working with IT ticketing systems such as ServiceNow, Zendesk, or Freshdesk and maintaining effective service standards.
- Executive level end user support and handling sensitive or confidential information.
- Strong troubleshooting across end user devices, operating systems, applications, identity, access, and connectivity.
- Windows, MacOS, and iOS lifecycle management.
- Administration of Microsoft 365 and Microsoft Entra ID, including user lifecycle, access management, security groups, licensing, authentication, and related services.
- Endpoint and mobile device management using Microsoft Intune, Jamf, or equivalent tools as applicable.
- SSO, MFA, privileged access, and role-based access management concepts.
- Practical networking knowledge, including DNS, DHCP, wired and wireless networks, and common connectivity troubleshooting.
- Ability to assess technical risk, prioritize work, document decisions, and communicate recommendations to non-technical stakeholders.
Preferred Experience & Skills:
- Experience in a life sciences, biotech, manufacturing, software development, or other regulated environment.
- Experience supporting security or compliance programs such as Cyber Essentials, ISO 27001, or GDPR.
- Experience with backup, disaster recovery, and business continuity planning.
- Experience leading technical workstreams.
$130,000 - $135,000 a year
At ONI, we understand that a fulfilling career involves more than just challenging work - it's about enjoying a well-rounded experience. When you become a part of our team, you not only contribute to groundbreaking research but also enjoy a range of benefits designed to enhance your life both inside and outside the workplace.
As an equal opportunity employer, we prioritize fairness and respect, ensuring every team member thrives regardless of their background. But that's not all - our perks include:
Competitive Compensation We recognize and reward your talent. Enjoy a competitive salary that reflects your expertise and contributions, ensuring your hard work is recognized.
Flex PTO plus 11 federal holidays and 4 dedicated wellbeing days.
Gym Access via ARE: Sorrento Valley, Torrey Pines, and UTC
401K via ADP
Life Insurance
Medical
Dental
Vision
Perks at Work: Enjoy exclusive discounts and deals through our perks at work program, adding value to your everyday life.
If you are driven by innovation, eager to make a significant impact in the realm of scientific and medical research
- A leading IT services provider is seeking an experienced IT Operations Project Manager to manage technology projects and facilitate IT process improvements. The ideal candidate will have 7 years of IT experience and at least 5 years of Project Management expertise. Strong...SuggestedRemote work
$130k - $135k
...to-day delivery and continuous improvement of ONI’s internal IT environment across our sites in the USA and UK, as well as supporting... ...in other locations. Serve as the senior hands-on technical lead for IT operations, working closely with ONI’s outsourced IT support provider...SuggestedFull timeWork at officeLocal areaRemote workFlexible hours- Clinically AI in San Diego is hiring an IT Manager to own the day-to-day operation of workforce technology and systems, ensuring secure provisioning, device compliance, and smooth IT infrastructure as we scale rapidly. This role emphasizes ownership from onboarding to...Suggested
$142.4k - $213.6k
...Technology Group, Information Technology Group > IT Project Management General Summary Serves as a strategy and operations leader and chief of staff to the VP of IT and... ...'s degree. Proven ability and experience leading large-scale data and analytics transformation...SuggestedFull timeWork experience placementWork from home$130k - $195k
Cooley LLP is seeking an IP Docketing & Data Manager to oversee the patent docketing function and manage the integrity of our IP data. The ideal candidate should have 5+ years of experience in an IP-related role and strong project management capabilities. This position ...SuggestedWork at officeRemote work- ...Category Org: Store Assistant Manager Job Description Job Duties • Operate all equipment. • Stock ingredients from delivery area to storage... ...orders both over the phone and in person. Ability to train and lead. Essential Functions/Skills Ability to add, subtract, multiply...Full timeWork at officeFlexible hoursShift work
- A national pizza delivery company in Chula Vista is seeking delivery personnel. Responsibilities include operating equipment, delivering products, and managing inventory. Candidates must have a valid driver's license, access to an insured vehicle, and be able to pass a...
- Intuit is seeking an AI & Technology Enablement lead for the Expert Network COE in San Diego. You will own the technology layer, govern the escalation ecosystem, and partner with product and engineering to align roadmaps with expert experience goals. You will drive readiness...
- Pava Applications International Corporation in San Diego, CA is seeking an Information Technology Manager to lead IT operations, security, and infrastructure for our SaaS environment. This on-site role emphasizes hands-on leadership and cross-functional collaboration....
$80k - $100k
...Job Description Job Description The Technical Support Operations Lead is responsible for driving operational excellence, accountability, and continuous improvement across the Technical Support organization. This role ensures support operations run efficiently by coordinating...Temporary workLocal areaImmediate startRemote workWorldwideFlexible hoursNight shift$124k - $170k
An innovative consumer product company in San Diego is looking for an IT Project & Portfolio Manager to lead IT project management and program initiatives across multiple regions. This hybrid role requires candidates to be local to San Diego and involves collaboration...Local area$132k - $172k
...project plans, timelines, and resource forecasts.Ensure effective communication of project status, risks, and opportunities; improve operational efficiency.Facilitate team meetings, prepare agenda, publish meeting minutes, and ensure accountability for deliverables.Monitor...- ABS Kids in Chula Vista, CA is hiring an Operations Manager to keep our centers running smoothly as we deliver evidence-based ABA therapy to children with autism. You will oversee daily operations, lead the administrative and clinical support teams, manage scheduling, inventory...
- ...Diego State University’s Information Technology Division seeks an experienced Administrative Analyst/Specialist III to lead complex business operations, financial and cost recovery administration, and project portfolio governance across the division. This senior role...
- General Dynamics Ordnance and Tactical Systems in San Diego is seeking a Project Manager Specialist to support daily operations, including administration for the General Manager and coordination across supply chain contracts, finance, and pricing. You will obtain quotes...Contract work
- BKF is seeking a Project Operations Manager to lead the administrative and operational functions of the Survey project delivery team. You will drive budgets, staffing, contracts, compliance, and process improvements across multiple projects and disciplines. You will support...
$189k - $246k
...community, and collaboration to pursue our vision of becoming a leading biopharmaceutical company dedicated to the delivery of... ...service for rare patients.Position Summary:The Director, Technical Operations (Small Molecule CMC) will provide technical oversight for small...Full timeTemporary work$150k - $195k
...Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** Summary:The Associate Director, Technical Operations, Biologics Drug Substance Manufacturing is responsible for providing technical expertise and operational leadership and support for...Contract work- A leading grocery retailer is seeking a Full-Time Assistant Store Manager in San Diego, CA. In this role, you will assist with managing store activities, oversee team performance, and ensure adherence to policies. Ideal candidates will have a High School diploma or equivalent...Hourly payFull time
- Exos Partners, LLC seeks an Assistant Operations Manager to join our San Diego team. You will develop, coordinate and maintain day-to-day operations across programs while staying current on internal products and implementing updates. You will support systems, vendors,...
- Dynamic Solutions Technology, LLC in San Diego, CA is seeking a full-time Operations Analyst III to support client operations. The ideal candidate will analyze organizational efficiency and apply advanced analytical techniques while ensuring optimal resource management...Full time
- Concentra in San Diego, CA, is seeking a Center Operations Director to lead center operations, oversee patient flow, and support clinicians to deliver high-quality care. This role emphasizes patient experience, staff leadership, and regulatory compliance within a busy medical...
$17.5 per hour
...Chula Vista, offering a pay rate of $17.50 per hour for 25 hours per week. The role involves assisting the Store Manager with daily operations, staff supervision, and ensuring customer satisfaction. Ideal candidates will have a high school diploma or GED, prior retail...Hourly payPart time- A major financial institution is seeking a Branch Operations Lead in Chula Vista, CA. The role focuses on managing branch operations, enhancing client experiences, and ensuring adherence to banking regulations. Candidates should have 1+ years of retail banking experience...Full timeWork at office
- Zentalis is looking for a Manager of Medical Affairs Operations to strategically lead operational initiatives. This role involves managing budgets, overseeing vendor engagement, and optimizing processes across medical initiatives. The ideal candidate has over 8 years of...
- SBM Management Services, LP is seeking a CSR Lead in San Diego to oversee cleanliness and sanitation of assigned areas and provide some directional support to custodial staff. The role involves operating cleaning equipment, tracking supplies, and coordinating with the...
- ...maintenance in line with FAA and customer requirements. The role provides leadership, directs maintenance and inspection activities, and coordinates staffing, training, and program support to ensure seamless operations and program success. #J-18808-Ljbffr General Atomics
$225k
...while also implementing structure, organization, and long-term operational systems. This is an excellent opportunity for a seasoned Estate... ..., including renovations and vendor oversight Proven ability to lead and collaborate with staff and vendors Hands-on, proactive mindset...For contractorsWork at office- A popular fast-food restaurant chain is seeking an Assistant Manager in San Diego, California. You will support the Restaurant General Manager by managing work shifts and performing administrative tasks. Responsibilities include ensuring the consistency of service and food...Shift work
- Sprouts Farmers Market in San Diego seeks an Assistant Bakery Manager to lead Bakery Clerks and support the Bakery Manager in daily operations, ensuring product quality, merchandising, and exceptional customer service in a fast-paced environment. You’ll manage inventory...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to IT Operations Lead. Be the first to apply!
- network operations center team lead San Diego, CA
- operations lead San Diego, CA
- operations leader San Diego, CA
- hotel operations intern San Diego, CA
- operations support technician San Diego, CA
- aviation operations San Diego, CA
- vice president hotel operations San Diego, CA
- senior operations technician San Diego, CA
- cannabis operations San Diego, CA
- venue operations San Diego, CA


